Products of Plant and Animal origin as Modifiers of Active Systems Drug Metabolism: Pharmacogenetic Aspect
Abstract
The paper deals with the topical issue of the drug’s interactions with components of commonly used food and remedies of traditional medicine (folk medicine). Similar studies are needed for a personalized approach to the treatment. In particular, the effect of traditional and new food, plants, which are used in traditional medicine, the characteristics of the person's lifestyle on the activity of enzymes of the family of cytochrome P-450 involved in the metabolism of drugs and actively studied in pharmacogenetic studies has been shown. Presented problematics is the basis for a thorough gathering of the medical history referring to the ways of life (food, bad habits) of the patient in the appointment of appropriate therapy.
About the Authors
O. V. Filiptsova
National University of Pharmacy
Ukraine
Ukraine
Filiptsova Olga Vladimirovna, Doctor. biol. Sciences, Associate Professor / Doctor of Biology, Assistant Professor
61002, Kharkov, Pushkinskaya str., 53
Tel. (fax) 0984099100, 0956614988
M. N. Kobets
The National University of Pharmacy
Ukraine
Ukraine
Kobets Marina Nikolaevna, Candidate of Pharmacy, Assistant Professor
61002, Kharkov, Pushkinskaya str., 53
Tel. (fax) 0686066154
Yu. N. Kobets
The National University of Pharmacy
Ukraine
Ukraine
Kobets Julia Nikolaevna, Candidate of Pharmacy, Assistant Professor
61002, Kharkov, Pushkinskaya str., 53
Tel. (fax) 0686066155
I. S. Burlaka
The National University of Pharmacy
Ukraine
Ukraine
Burlaka Irina Sergeevna, Candidate of Pharmacy, Assistant
61002, Ukraine, Kharkov, Pushkinskaya str., 53
Tel. (fax) 0985940901
I. A. Timoshyna
The National University of Pharmacy
Russian Federation
Russian Federation
Timoshina Irina Alexandrovna, Senior laboratory assistant
61002, Kharkov, Pushkinskaya str., 53
Tel. (fax) 0501503471
References
1. A phase 1 study to evaluate the safety and pharmacokinetics of bosutinib (Bosulif®) in pediatric patients with chronic myeloid leukemia who are resistant or intolerant to at least one prior tyrosine kinase inhibitor therapy // Pfizer. - 2014. Protocol Number: B1871015. – 110 p.
2. Arayne M.S. Grape fruit juice-drug interactions / M.S. Arayne, N. Sultana, Z. Bibi // Pak J Pharm Sci. – 2005. – Vol.18, № 4. – P.45-57.
3. Bailey D.G. Bergamottin, lime juice, and red wine as inhibitors of cytochrome P450 3A4 activity: comparison with grapefruit juice / D.G. Bailey, G.K. Dresser, J.R. Bend // Clin Pharmacol Ther. – 2003. – Vol.73, № 6. – P.529-37.
4. Chatuphonprasert W. Impact of six fruits--banana, guava, mangosteen, pineapple, ripe mango and ripe papaya--on murine hepatic cytochrome P450 activities / W. Chatuphonprasert, K. Jarukamjorn // J Appl Toxicol. – 2012. – Vol.32, №12. – P.994-1001.
5. Diluted bee venom injection reduces ipsilateral mechanical allodynia in oxaliplatininduced neuropathic mice / S.Y. Yoon, J.H. Yeo, S.D. Han [et al.] // Biol Pharm Bull. – 2013. – Vol.36, № 11. – P.1787-93.
6. Effect of green tea extracts on oxaliplatin-induced peripheral neuropathy in rats / J.S. Lee, Y.T. Kim, E.K. Jeon [et al.] // BMC Complement Altern Med. – 2012. – Vol.12, № 124 (doi: 10.1186/1472-6882-12-124).
7. Effect of honey on CYP3A4, CYP2D6 and CYP2C19 enzyme activity in healthy human volunteers / T. Tushar, T. Vinod, S. Rajan [et al. ]// Basic Clin Pharmacol Toxicol. – 2007. – Vol.100, №4. – P.269-72.
8. Effect of St John's wort on drug metabolism by induction of cytochrome P450 3A4 enzyme / J.S. Markowitz, J.L. Donovan, C.L. DeVane [et al.] // JAMA. – 2003. – Vol.290, №11. – P.1500-4.
9. Effect of synthetic eel calcitonin, elcatonin, on cold and mechanical allodynia induced by oxaliplatin and paclitaxel in rats / M. Aoki, A. Mori, T. Nakahara [et al.] // Eur J Pharmacol. – 2012. – Vol.696, №1-3. – P.62-9.
10. Effects of garlic (Allium sativum L.) supplementation on cytochrome P450 2D6 and 3A4 activity in healthy volunteers / J.S. Markowitz, C.L. Devane, K.D. Chavin [et al.] // Clin Pharmacol Ther. – 2003. – Vol.74, №2. – P.170-7.
11. Haber S.L. Cranberry and warfarin interaction: a case report and review of the literature / S.L. Haber, K.A. Cauthon, E.C. Raney // Consult Pharm. – 2012. – Vol.27, №1. – P.58-65.
12. In-vitro inhibitory effect of Tualang honey on cytochrome P450 2C8 activity / Y.D. Muthiah, C.E. Ong, S.A. Sulaiman [et al.] // J Pharm Pharmacol. – 2012. – Vol.64, №12. – P.1761-9.
13. Salmon calcitonin reduces oxaliplatin-induced cold and mechanical allodynia in rats / M. Aoki, A. Mori, T. Nakahara [et al.] // Biol Pharm Bull. – 2013. – Vol.36, №2. – P.326-9.
14. The effect of curcumin on oxaliplatin and cisplatin neurotoxicity in rats: some behavioral, biochemical, and histopathological studies / M.S. Al Moundhri, S. Al-Salam, A. Al Mahrouqee [et al.] // J Med Toxicol. – 2013. – Vol.9, №1. – P.25-33.
15. The effect of variable cigarette consumption on the interaction with clozapine and olanzapine / T. Haslemo, P.H. Eikeseth, L. Tanum [et al.] // Eur J Clin Pharmacol. – 2006. – Vol.62, №12. – P.1049-53.
Review
For citations:
Filiptsova O.V., Kobets M.N., Kobets Yu.N., Burlaka I.S., Timoshyna I.A. Products of Plant and Animal origin as Modifiers of Active Systems Drug Metabolism: Pharmacogenetic Aspect. Yakut Medical Journal. 2014;(4):60-62.
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