Brown Adipose Tissue and Extremely Cold Climate
Abstract
In the article a case of verification of brown adipose tissue was described at a patient of 54 years old, a resident of the coldest city in the world Yakutsk. The brown adipose tissue was revealed in adipose tissue samples with para-aortic, perirenal, subclavian and perityroid areas. The abdominal fat was introduced by typical white adipose tissue.
About the Authors
M. I. Tomskiy
FGBNU "YSC CMP"
Russian Federation
Russian Federation
Tomskiy Mikhail Innokentievich - MD, professor, director
Yakutsk
S. Chinti
Center for the Study of Obesity, University of Ancona
Italy
Italy
Saverio Cinti - Ph.D., MD, professor of anatomy, director
D. G. Tikhonov
NEFU named after M.K. Ammosov
Russian Federation
Russian Federation
Tikhonov Dmitry Gavrilevich - MD, professor of Health Research Institute
Yakutsk
K. S. Loskutova
RB № 1- NCM MH Sakha (Yakutia)
Russian Federation
Russian Federation
Loskutova Kyunnyay Savvichna - PhD, Head. Department of Pathomorphology
Yakutsk
E. A. Isakov
RB № 1- NCM MH Sakha (Yakutia)
Russian Federation
Russian Federation
Isakov Evgeniy Andreevich - doctor pathologist
Yakutsk
References
1. Andersen S. Thyroid hyperactivity with high thyroglobulin in serum despite sufficient iodine intake in chronic cold adaptation in an Arctic Inuit hunter population / Andersen S., Kleinschmidt K., Hvingel B., Laurberg P. // Eur. J. Endocrinol. -2012. - 166(3). ─ P. 433-440.
2. Cinti S. Distribution and development of brown adipocytes in the murine and human adipose organ / Frontini A., Cinti S. // Cell Metab.- 2010. -11(4). ─ P. 253-256.
3. Cold-activated brown adipose tissue in healthy men / van Marken Lichtenbelt W.D., Vanhommerig J.W., Smulders N.M. [et al.] // N. Engl. J. Med. – 2009. - 360 (15). ─ P. 1500-1508.
4. Functional brown adipose tissue in healthy adults / Virtanen K.A., Lidell M.E., Orava J.[et al.] // N. Engl. J. Med. – 2009 - 360(15). ─ P. 1518- 1525.
5. Identification and importance of brown adipose tissue in adult humans / Cypess A.M., Lehman S., Williams G.[et al.] // N. Engl. J. Med. – 2009 - 360(15). ─ P. 1509-1517.
6. Levy S.B. An assessment of infrared thermal imaging as an indirect method for quantifying variation in brown adipose tissue using data from the Indigenous Siberian Health and Adaptation Project / Levy S.B., Leonard W.R., Tarskaia L.A. [et al.] // American Journal of Human Biology. – 2014. ?? 26). ─ P. 270 -270.
7. The presence of UCP1 demonstrates that metabolically active adipose tissue in the neck of adult humans truly represents brown adipose tissue/ Cinti S., Cannon B., Nedergaard J. [et al.] // FASEB J..- 2009. - 23(9). ─ P. 3113-3120.
Review
For citations:
Tomskiy M.I., Chinti S., Tikhonov D.G., Loskutova K.S., Isakov E.A. Brown Adipose Tissue and Extremely Cold Climate. Yakut Medical Journal. 2015;(1):44-45.
Views:
10
Email this article 