Indicators of peripheral blood at experimental cold exposure
https://doi.org/10.25789/YMJ.2018.62.03
Abstract
The article presents the results of an experimental study, the purpose of which was to study changes in the cellular composition of the blood of rats depend of their exposure time to cold. The obtained results indicate that the cold affects the activity of cells that provide nonspecific and specific immune responses.
It is shown that the exposure of rats in our experiment for 7 to 30 days had a fairly long-term effect, as it led to suppression of the activity of monocytes and neutrophils. However, we observed an increase in the number of leukocytes on day 14, which may be due to a short-term stimulation of leukocytopoiesis. The number of lymphocytes in our study remained elevated throughout the experiment, maximally increasing by 7 and 30 days. We were also able to demonstrate a decrease in the number of platelets, which was an appropriate reaction of the body in response to cold exposure, as platelets take a direct part in the repair processes observed when the tissue is damaged by cold, and also improve the migration of leukocytes to the focus of inflammation. An increase in hematocrit was also established, which is one of the signs of a reaction to cold stress.
Thus, the present study revealed patterns of changes in the cellular composition of peripheral blood during cold stress in the experiment, which were expressed in the features of the reaction from erythrocytes, platelets and leukocytes.
About the Authors
L. I. Arzhakova
M.K. Ammosov NEFU Medical Institute
Russian Federation
Russian Federation
Arzhakova Lena Ignatevna, Candidate of Medical Sciences Docent
+79644150606
Yakutsk
D. K. Garmaeva
M.K. Ammosov NEFU Medical InstituteDocent
Russian Federation
Russian Federation
Garmaeva Darima Kyshektovna, Doctor of Medical Sciences, Professor, Docent
+79142349680
T. I. Dmitrieva
Federal State Budget Educational Institution “Yakut State Agricultural
Academy”
Russian Federation
Russian Federation
Dmitrieva Tuyara Ivanovna, Candidate
+79644298776
A. I. Fyodorova
M.K. Ammosov NEFU Medical Institute
Russian Federation
Russian Federation
Fedorova Aida Ivanovna, Candidate of Medical Sciences Docent
+79241696871
D. S. Belolubksaya
M.K. Ammosov NEFU Medical Institute
Russian Federation
Russian Federation
Belolyubskaya Dariya Stepanovna, Candidate of Medical Sciences Docent
+79142976118
O. G. Afanaseva
M.K. Ammosov NEFU Medical Institute
Russian Federation
Russian Federation
Afanasyeva Oksana Gavrilovna, Candidate of Medical Sciences Docent
+79142671992
A. I. Egorova
M.K. Ammosov NEFU Medical Institute
Russian Federation
Russian Federation
Egorova Angelina Innokentievna, Candidate of Biological Sciences,
Junior Research Associate Docent
+79148220249
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Review
For citations:
Arzhakova L.I., Garmaeva D.K., Dmitrieva T.I., Fyodorova A.I., Belolubksaya D.S., Afanaseva O.G., Egorova A.I. Indicators of peripheral blood at experimental cold exposure. Yakut Medical Journal. 2018;(2):12-14. https://doi.org/10.25789/YMJ.2018.62.03
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