Features of stress-implementing and regulatory systems of the body of medical students in high latitudes
https://doi.org/10.25789/YMJ.2023.82.15
Abstract
The aim of the study was to study the influence of the level of situational (SA), personal anxiety (PA) on the psycho-emotional state of the body and the cardiovascular system (CS) in high latitudes.
At the functional level of the work of the cardiovascular system, significant differences were found in the form of changes in the temporal and frequency characteristics of the HRV, in which the influence of the mechanisms of sympathetic modulation of the heart rhythm prevails. The functional state of the hypothalamic-pituitary-adrenal system (HPAS), estimated as the quantitative content of cortisol in the blood and does not change depending on the level of anxiety. Significant differences in the level of vitamin D in the blood and its general deficiency in the study participants were shown.
Keywords
About the Author
S. V. PryanichnikovRussian Federation
Apatites
References
1. Avtsyn A.P. Introduction to geographical pathology. M.: Medgiz, 1972. 328 p.
2. Baevsky R. M., Ivanov G. G., Chireikin L. V. Methodological recommendations for HRV analysis using various electrocardiographic systems // Bulletin of Arrhythmology. 2001. No. 24. pp. 65-87.
3. Influence of menstrual cycle phases on the state of the hypothalamic-pituitary-adrenal system in practically healthy women of Novosibirsk / Fedina, R. G., [et al.]. Journal of Siberian Medical Sciences, 2011. (6), p. 15.
4. Boyko E.R. Physiological and biochemical foundations of human life in the North. Yekaterinburg: Ural Branch of the Russian Academy of Sciences, 2005. 192 p.
5. Diatroptov M.E., Simonova E.Yu., Diatroptova M.A. Infradian rhythms of changes in the level of cortisol and thyroid hormones in women of reproductive age // Russian Medico-Biological Bulletin named after academician I.P. Pavlov. 2013. VOL.21. No.3. p. 107-113. doi: 10.17816/PAVLOVJ20133107-113
6. Eliseev O.P. Practicum on personality psychology: 2<sup>nd</sup> ed., corrected and reprinted in St. Petersburg: Peter, 2002. 512 p.
7. Kadochnikova N. I., Khlybova, S. V. The state of menstrual function, the level of somatic and reproductive health of girls aged 17-19 years with different duration of the menstrual cycle // Medical Almanac, 2008. (4). pp. 89-92.
8. Kaznacheev V.P. Problems of adaptation and human constitution in the North // Institute of Clinical and Experimental Medicine of the SB Academy of Medical Sciences of the USSR, Novosibirsk, Vol.4. No. 1. 1984. pp. 95-99.
9. Kaznacheev V.P. Problems of adaptation and human constitution in the North. Human environmental problems in the Far North. Novosibirsk, 1980. 208 p.
10. Korolenko Ts.P. Human psychophysiology in extreme conditions. M.: "Medicine", 1978. 272 p.
11. Mikhailov V. M. Heart rate variability (a new look at the old paradigm). Ivanovo: LLC "Neurosoft", 2017. 516 p.
12. Human pathology in the North / Avtsyn A.P., Zhavaronkov A.A., Marachev A.G., Milovanov A. P. M.: Medicine. 1985. 416 p.
13. Rean A. A., Averin V.A., Dandarova Zh.K. Human psychology from birth to death. Edited by A.A. Rean. St. Petersburg: Prime - EUROZNAK, 2003. 656 p.
14. Results of preventive medical examinations of minors in the Russian Federation. Baranov A.A., [et al.] // Russian Pediatric Journal. 2016. 19 (5). pp. 287-293.
15. Test of differentiated self-assessment of functional state / Doskin V.A., Lavrentieva N.A., Miroshnikov M.P., Sharai V.B. // Questions of psychology. 1973. No. 6. pp.141-145.
16. Tyukalova M. A., Rechkalov A.V. The level of cortisol in blood serum at rest and during exercise in different phases of the ovarian-menstrual cycle // Bulletin of Kurgan State University, 2017. (3 (46)). pp.18-19.
17. Khasnulin V.I. Polar stress syndrome // Medical and ecological foundations of the formation, treatment and prevention of diseases in the indigenous population of the Khanty–Mansi Autonomous Okrug. Novosibirsk, 2004. pp.24-35.
18. Khasnulin V.I., Khasnulin P.V. Modern ideas about the mechanisms of formation of northern stress in humans at high latitudes // Human Ecology, 2012. No. 1. pp. 3-11. doi: 10.33396/1728-0869-2012-1-3-11
19. Chronobiology and chronomedicine : monograph / Collective of authors edited by S. M. Chibisov, S. I. Rappoport, M. L. Blagonravov. Moscow: RUDN, 2018. 828 p.
20. Tsaregorodtsev N.A., Ivanova O.V., Dianov O.A. The state of the hemostasis system in children with metabolic syndrome. Tomsk. Bulletin of Siberian Medicine, 2015; 14 (5): pp. 100-105.
21. Boucher B.J. Is vitamin D status relevant to metabolic syndrome? Dermato-Endocrinology 2012. 4(2). pp. 212–224. doi: 10.4161/derm.20012
22. Circulating 25-hydroxy-vitamin D and risk of cardiovascular disease: Ameta-analysis of prospective studies / Wang L., [et al.]. Circ Cardiovasc Qual Outcomes, 2012. 1; 5: pp. 819–829. doi: 10.1161/circoutcomes.112.967604
23. Hewison M. Vitamin D and immune function: autocrine, paracrine or endocrine? Scand J Clin Lab Invest (Suppl.) 2012; 243: pp. 92–102. doi: 10.3109/00365513.2012.682862
24. Łagowska K. The Relationship between Vitamin D Status and the Menstrual Cycle in Young Women: A Preliminary Study. Nutrients, 2018. 10(11):1729. doi: 10.3390/nu10111729.
25. Lower levels of plasma 25-hydroxyvitamin D among young adults at diagnosis of autoimmune type 1 diabetes compared with control subjects: results from the nationwide / Littorin B., Blom P., Schölin A. [et al.]. Diabetes Incidence Study in Sweden (DISS). Diabetologia 2006; 49: pp. 2847–2852. doi: 10.1007/s00125-006-0426-x
26. Multifactorial explanatory model of depression in patients with rheumatoid arthritis: a structural equation approach / Santos E.F., [et al.]. Clin. Exp.Rheumatol, 2019. Vol. 37(4). pp. 641-648.
27. Pu D., Luo J., Wang Y. Prevalence of depression and anxiety in rheumatoid arthritis patients and their associations with serum vitamin D level. Clin.Rheumatol, 2018. Vol.37(1). pp. 179-184. DOI: 10.1007/s10067-017-3874-4
28. Raghuwanshi A., Joshi S.S., Christakos S. Vitamin D and multiple sclerosis. J Cell Biochem, 2008; 105: pp. 338–343. doi: 10.1002/jcb.21858
29. Relation of vitamin D deficiency to cardiovascular risk factors, disease status, and incident events in a general healthcare population / Anderson J.L., [et al.]. Am J Cardiol 2010; 106: pp. 963–968. doi: 10.1016/j.amjcard.2010.05.027
30. Subramanian A., Gernand A.D. Vitamin D metabolites across the menstrual cycle : a systematic review. BMC Women's Health 19, 19 (2019). doi: 10.1186/s12905-019-0721-6
31. Task Force of the European Society of Cardiology and the North American Society of Pacing and Electrophysiology. Heart Rate Variability. Standards of Measurement, Physiological Interpretation and Clinical Use // Circulation. 1996. Vol. 93. pp. 1043–1065.
32. Vitamin D and Reproductive Hormones Across the Menstrual Cycle / Harmon Q. E., [et al.]. Human Reproduction, Vol. 35, Issue 2, 2020, pp. 413–423, doi: 10.1093/humrep/dez283
33. Vitamin D, cardiovascular disease and mortality / Pilz S., [et al.]. Clin Endocrinol (Oxf) 2011. 75: pp. 575–584. doi: 10.1111/j.1365-2265.2011.04147.x
34. Vitamin D status in children and young adults with inflammatory bowel disease / Pappa H.M., [et al.]. Pediatrics, 2006; 118: pp.1950–1961. doi: 10.1542/peds.2006-0841
35. 25-hydroxyvitamin D, IGF-1, and metabolic syndrome at 45 years of age: a cross-sectional study in the 1958 British Birth Cohort / Hyppönen E., [et al.]. Diabetes 2008; 57: pp. 298–305. doi: 10.2337/db07-1122
Review
For citations:
Pryanichnikov S.V. Features of stress-implementing and regulatory systems of the body of medical students in high latitudes. Yakut Medical Journal. 2023;(2):61-67. https://doi.org/10.25789/YMJ.2023.82.15