Diagnostic significance of the human papilloma virus detection in blood

There is still no clear understanding of the human papillomavirus infecting, as well as its eliminating process from the body. It is known that cervical cancer is caused by human papillomavirus in 99 percent of cases, but only in a small number of human papillomavirus infected women leads to develop cervical cancer. At the same time, based on cytological and histological analysis of the women cervical samples, it is currently impossible to establish criteria that would indicate the malignant progression possibility. Blood, as a unique tissue with specific and nonspecific protective adaptive mechanisms, can be a source of crucial information about the human body papillomavirus infecting. The article provides an overview of the research devoted to the human papillomavirus detection in blood and identifies unresolved issues arising from these studies.

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