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Interrelation between the concentrations of bone remodeling markers, osteoporosis and the risk of pathological bone fractures in patients with rheumatoid arthritis

https://doi.org/10.25789/YMJ.2019.68.10

Abstract

The article reports the study of possibility of predicting bone fractures by determining the concentration of bone remodeling markers in patients with rheumatoid arthritis (RA).
It was revealed that at RA, complicated by osteoporosis, as well as in the presence of pathological bone fractures in patients, an increase in C-telopeptide type I collagen, serum P1NP, urine calcium / creatinine, and a decrease in serum 25-OH vitamin D are observed.

About the Authors

Yu. R. Akhverdyan
Federal State Budgetary Institution “Research Institute of Clinical and Experimental Rheumatology named after A.B. Zborovsky ”
Russian Federation

Akhverdyan Yury R. - PhD in Medicine, Senior Researcher at the Laboratory of methods for the treatment and prevention of joint diseases

400138, Volgograd, 76 Zemlyachki St., phone (work): (8442) 789098



B. V. Zavodovsky
Federal State Budgetary Institution “Research Institute of Clinical and Experimental Rheumatology named after A.B. Zborovsky"
Russian Federation

Zavodovsky Boris V. - Doctor of Medical Sciences, Deputy Director for Scientific Issues

the head of laboratory of methods of treatment and prevention of joint diseases

address: 400138, Volgograd, 76 Zemlyachki St., tel. work: (8442) 78-90-93



Yu. V. Polyakova
Federal State Budgetary Institution “Research Institute of Clinical and Experimental Rheumatology named after A.B. Zborovsky”
Russian Federation

Polyakova Yulia V. - PhD in Medicine, Researcher

400138, Volgograd, 76 Zemlyachki St., tel.: (8442) 78-90-93



L. E. Seewordova
Federal State Budgetary Institution “Research Institute of Clinical and Experimental Rheumatology named after A.B. Zborovsky”
Russian Federation

Seewordova Larisa E. - PhD in Medicine, leading researcher at the laboratory of methods for the treatment and prevention of joint diseases

400138, Volgograd, 76 Zemlyachki St., tel. office: (8442) 78-90-93



E. V. Papichev
Federal State Budgetary Institution “Research Institute of Clinical and Experimental Rheumatology named after A.B. Zborovsky"
Russian Federation

Papichev Evgeny V. - Junior Researcher at the Laboratory for Methods of Treatment and Prevention of Joint Diseases

400138, Volgograd, 76 Zemlyachki St., tel. office: (8442) 78-90-93



References

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Review

For citations:


Akhverdyan Yu.R., Zavodovsky B.V., Polyakova Yu.V., Seewordova L.E., Papichev E.V. Interrelation between the concentrations of bone remodeling markers, osteoporosis and the risk of pathological bone fractures in patients with rheumatoid arthritis. Yakut Medical Journal. 2019;(4):43-45. https://doi.org/10.25789/YMJ.2019.68.10

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ISSN 1813-1905 (Print)
ISSN 2312-1017 (Online)