Cytological analysis of cervix inflammatory diseases in different age groups on the example of the Sakha (Yakutia) Republic
https://doi.org/10.25789/YMJ.2018.64.03
Abstract
Cytological analysis of cervix inflammatory diseases was conducted on women aged 18 to 88. The results of the analysis showed a high incidence of disease in the age groups 18-29. In the middle age group (30-44 and 45-59 years), balancing of genital infections is noted and the first effects of infection with viral infections appear (dysplasias of varying severity and background changes in the epithelium). In women in the older age group, mainly inflammatory processes (atrophic colpitis) were observed, which is associated with the intense influence of sex hormones. Generally, long-term preservation of viral HPV is associated with high-oncogenic risk types of HPV infection (mainly HPV 16). Remote causes of viral infection were found rarely (2.9%) on menopause, but it has the important prognostic value, which can predict the risk of cervical pathology development. Inflammation processes (senile vaginitis) are found in the old age group of women (20,9%), which is due to the intensive influence of sex hormones (estrogens). At this period the lack of estrogen harms the main protective properties of the stratified squamous epithelium. As a result, the number of lactobacilli is decreased or completely disappeared by the cause of conditionally pathogenic and pathogenic flora overgrowth.
Thus, infectious-inflammatory diseases of the female genital organs caused by various pathogens, sexually transmitted diseases, or nonspecific microflora, represent a serious medical and social problem.
Supporting agencies: This work is based on R&D ”Epidemiology aspects of cancer on the Far North living environment, development of methods for the prevention, diagnosis, treatment using the high-informative basic research methods (М06;01;01)» (№ 0556-2014- 0006).
About the Authors
M. P. Kirillina
M.K. Ammosov North Eastern Federal University
Russian Federation
Russian Federation
Kirillina Maria - candidate of Biological Sciences, Senior Research Scientist, Head of Yakut Science Centre of complex medical problems laboratory, Head of M.K. Ammosov North Eastern Federal University Medical Institute Clinic laboratory
A. K. Ivanova
M.K. Ammosov North Eastern Federal University
Russian Federation
Russian Federation
Ivanova Anna - clinical pathologist of M.K. Ammosov North Eastern Federal University Medical Institute Clinic
E. L. Lushnikova
Federal State Budget Scientific Institution «Federal Research Center of Fundamental and Translational Medicine»
Russian Federation
Russian Federation
Lushnikova Elena Leonidovna: Doctor of Biological Sciences, Professorб Head of Institute of Molecular Pathology and Pathomorphology
630117, Novosibirsk, Timakov’s Str., 2
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Review
For citations:
Kirillina M.P., Ivanova A.K., Lushnikova E.L. Cytological analysis of cervix inflammatory diseases in different age groups on the example of the Sakha (Yakutia) Republic. Yakut Medical Journal. 2018;(4):12-15. https://doi.org/10.25789/YMJ.2018.64.03
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