Evaluation of sub-population composition of lymphocytes in chronic toxic liver disease and anemia of chronic disease on the background of transmitted infiltrate pulmonary tuberculosis
https://doi.org/10.25789/YMJ.2018.64.02
Abstract
The article presents the results of the estimation of the subpopulation composition of lymphocytes in 66 patients with chronic toxic liver damage and anemia of a chronic disease on the background of the transferred infiltrative pulmonary tuberculosis. The use of a combination of sirepar and sodium nucleate in the treatment of such patients contributes to the elimination of the clinical phenomena of the combined pathology, and along with the improvement or complete normalization of the clinical indices in the patients examined, normalization of the cellular immunity parameters was noted, which gives grounds for recommendations on the use of the proposed combination of drugs in the complex treatment.
About the Authors
N. S. Sidorova
Lugansk people`s republic Saint Luka state medical university
Russian Federation
Russian Federation
Nataliya Sidorova, Assistant of the Department of Phthisiology, Clinical Immunology and Medical Genetics of the State establishment
Ya. A. Sotskaya
State establishment of Lugansk people`s republic Saint Luka state medical university
Russian Federation
Russian Federation
Sotskaya Yana, Doctor of Medical Sciences, Professor, Head of the Department of Infectious Diseases and Epidemiology named after V. M. Frolov
References
1. Antonenko O.M. Toxic liver damage: ways of pharmacological correction / O.M. Antonenko // Medical Council. – 2013. – №6. – P. 45-51. DOI: 10.21518/2079-701x-2017-0-33-37.
2. Drel V.F. Parameters of hepatic markers of blood serum with toxic damage of the liver before and after physical exertion / V.F. Drel, A.A. Vinogradov // Scientific Gazette. – 2013. – №25 (168). – Issue 24/1. – P. 179- 182.
3. Ilchenko L.Yu. Medicinal disease of the liver / L.Yu. Ilchenko, T.I. Korovich // The role of hepatoprotectors in its therapy. – Medical advice. – 2013. – №10. – P. 32-37.
4. Inyakova N.V. Prevalence and methods of correction of iron metabolism disorders in tuberculosis infection: author’s abstract PhD diss. ...; Federal Scientific and Clinical Center of Pediatric Hematology, Oncology and Immunology of the Federal Agency for Health Care / N.V. Inyakova. – Ryazan, 2011. – 26 p.
5. Knyazkova I.I. Anemia of chronic diseases / I.I. Knyazkova // Health of Ukraine. – 2016. – №5. – P. 48-49.
6. Drug-induced liver damage. Diagnostics and treatment / A.V. Kovtun, A.V. Yakovenko, A.N. Ivanov [et al.] // Gastroenterology. – 2011. – №2. – Р. 35-41.
7. Kozlov A.P. Medical statistics: textbook / A.P. Kozlov, N.N. Popov. – Kharkov: publish. Center of KhNU, 2006. – 88 p.
8. Medicinal lesions of the liver with persistent course in patients with tuberculosis / A.V. Bereznikov, A.V. Mordyk, V.P. Konev [et al.] // Tuberculosis and lung diseases. – 2010. – №4. – P. 43-46.
9. Mordyk A.V. Medicinal lesions of the liver and their treatment in the tuberculosis clinic / A.V. Mordyk, O.G. Ivanova, L.A. Nagibina [et al.] // Tuberculosis and diseases lungs. – 2015. – №9. – P. 47-52. DOI: 10.21145/2499-9954-2017-4-128-131.
10. Merkulov S.A. Modern estimation of the features of the medicinal liver damage in patients with pulmonary tuberculosis receiving specific therapy / S.A. Merkulov, M.V. Koroleva // Bulletin of VolgGMU. – 2012. – Issue 2 (42). – P. 19-22. DOI: 10.21145/2499-9954-2017-4-128-131.
11. Okovity S.V. Topical issues of the use of hepatotropic drugs: lectures for practicing doctors / S.V. Okovity // Proceedings of the 20th Anniversary of the National Congress «The Man and the Medicine». – M., 2014. – P. 386-408.
12. Petrenko V.I. The problem of tuberculosis in Ukraine / V.I. Petrenko, R.G. Protsyuk // Tuberculosis. Pulmonary Disease. HIV infection. – 2015. – №2 (21). – P. 16-29.
13. Bogun L. V. Anemia of chronic disease / L.V. Bogun // Journal of V. N. Karazin` KhNU. – 2015. – №1154. – P. 81-87.
14. Global TB report 2013 [e. resource] // http: //apps.who.int/iris/bitstream/10665/91355/1/9789241564656eng.pdf.
Review
For citations:
Sidorova N.S., Sotskaya Ya.A. Evaluation of sub-population composition of lymphocytes in chronic toxic liver disease and anemia of chronic disease on the background of transmitted infiltrate pulmonary tuberculosis. Yakut Medical Journal. 2018;(4):9-12. https://doi.org/10.25789/YMJ.2018.64.02
Views:
5
Email this article 