Distribution of carriers of “Indo-European” haplotypes of HLA system on the territory of Eurasia
https://doi.org/10.25789/YMJ.2019.67.32
Abstract
The age of the “Indo-European” haplotypes HLA-A1/B17 and HLA-A1/B8 is calculated for different populations of Eurasia. The obtained data are compared with historical events. The results show that the most ancient carriers of the HLA-A1/B17 haplotype are Latvians, and the HLA-A1/ B8 haplotype are the Turks. The distribution of the HLA-A1/B17 haplotype in populations is consistent with the migration patterns of Indo-European tribes. This is not observed for HLA-A1/B8; therefore, it has been suggested that the majority of Indo-European tribes did not have this haplotype. A definition of allele frequencies is proposed by directly counting the number of haplotypes by alleles without using the Bernstein formula.
About the Author
I. P. GuryevRussian Federation
Guryev Innokenty Pavlovich - Candidate of Agricultural Sciences
References
1. Aleхeev V.P. Caucosoid race in South Siberia and Central Asia, its participation in the origin of modern people / V.P. Alexeev // The descent of the aborigines of Siberia and their languages: Proceedings of the inter-university conference of May 11-13, 1969. – Tomsk 1969. - P. 196-198.
2. Bongard-Levin G.M. India in antiquity / G.M. Bongard-Levin, G.F. Ilyin. – M.: Nauka, 1985. – P. 738.
3. Evgrafov O.V. Genetic archeology: a new approach to the study of the genetic history of populations / O.V. Evgrafov // Reports RAS. – 1994. – V. 388, №6. - P. 822-826.
4. Yeremeev D.E. At the junction of Asia and Europe. Essays on Turkey and the Turks / D.E. Eremeev. – M.: Nauka, 1980. – P. 238.
5. Immunogenetic parameters of HLA (C and DR loci) of Minsk residents / G.V. Semenov [et al.] // Histocompatibility antigens and diseases. Sat scientific works. St-Peterburg. – 1991. - P. 9-16.
6. Matyushin G.N. Archeological dictionary / G.N. Matyushin. – M.: Enlightenment: AO “Teaching lit.”. – 1996. – 304 p.
7. Feature of the polymorphism of the genetic system HLA in the population of Khanty / Yu. V. Abramov [et al.] // Genetics. – 1990. – V. 26, №6. – P. 1087-1091.
8. Polymorphism of genes of the immune response and its role in anti-infective protection / R.M. Khaitov [et al.] // Immunology. – 2013. – №3. – P.132-144.
9. Population-genetic study of leykocyte antigens of the HLA system among residents of the south-eastern geographical zone of the USSR / L.I. Timoshenko [et al.] // Problems of hematology and blood transfusion. – 1992. – V. 27, №1. – P. 37-40.
10. The distribution of leykocyte antigens and the frequency of allosensitization to various antigens of the HLA system among the inhabitants of Nizhny Novgorod / I.M. Kazakova [et al.] // Histocompatibility antigens and diseases. Sat scientific w. St-Peterburg. – 1991. – P. 20-25.
11. Distribution of HLA-antigens in Buryat people / L.G. Sibiryakova [et al.] // Histocompatibility antigens and diseases. Sat scientific w., St-Peterburg, 1991. – P. 25-29.
12. Sibiryakova L.G. Distribution of HLA antigens of I and II classes among people of Yakut nationality / L.G. Sibiryakova, L.D. Serova, L.P. Alexeev // Ibid – 1991. P. 30-35.
13. Snell J. Compatibility of tissues / J. Snell, J. Dosse, S. Natenson // Trans. from English. – M.: Mir. – 1979. P. 502.
14. Sochnev A.M. The frequency of genes and gaplotypes of HLA,HLA-A, HLA-B antigens among Latviens /A.M. Sochnev // Immunology. – 1982. – №1. – P. 43-46.
15. Tananov A.T. HLA-system of antigens and its value in the transplantation of organs and tissues: scientific review / A.T. Tananov, R.M. Kutyina. – M.: - 1980. P. 60.
16. Udina I.G. Genetic polymorphism of the HLA-system in Komi and Komi-Permyak / I.G. Udina, G.S. Rautian // Genetics. – 1994. – V. 30 – №7. – P. 982-991.
17. Fomin M.M. About the connections of the Germanic and Turkic language / M.M. Fomin // Language – myth – the culture of the peoples of Siberia. – Yakutsk. – 1988. – P.49-55.
18. HL-A and Other Polymorphisms in Turks / A. Svejgaard, L. Staub Nielsen, C. Jersild [et al.] // Histocompatibility Testing. Published by Munksgaard, Copenhagen, Denmark. – 1972. – P. 139-146.
19. HLA polymorphism in Israel. IX. An overall comparative analysis / B. Bonne-Tamir, J.D. Bodmer, W.F. Bodmer [et al.] // Tissue Antigens, 1978. – V.11. – P. 235-250.
20. Solheim B.G. Study of the HL-A System in a West Pakistan Population / B.G. Solheim, Anne Bratlie & E. Thorsby // Histocompatibility Testing. Published by Munksgaard, Copenhagen, Denmark. – 1972. – P. 171-174.
21. Study of the HL-A System in the Nepalese Sherpa Population / E.D. Albert, J.D. Mcclelland, C. Hammer [et al.] // Ibid – 1972. – P. 227-232.
22. Study of the HL-A System in the Turkish and German Populations / E.D. Albert, S. Scholz, I. Rosenthal [et al.] // Ibid – 1972. – P. 147-152.
23. Fefelova V.V. Participation of Indo-European tribes in Ethnogeny of the Mongoloid population of Siberia: Analysis of the HLA Antigen distribution in Mongoloids of Sibеria / V.V. Fefelova // Amer. J. Hum. Genet. – 1990. – V. 47. – P. 294-301.
Review
For citations:
Guryev I.P. Distribution of carriers of “Indo-European” haplotypes of HLA system on the territory of Eurasia. Yakut Medical Journal. 2019;(3):115-119. https://doi.org/10.25789/YMJ.2019.67.32
Views:
4
Email this article 