Study of dopamine levels in peripheral venous blood and immune protection status in residents of northern territories of the Russian Federation according to health status

The correlation of dopamine concentration in peripheral blood with the level of immune protection in Northerners was studied. The registration level of elevated dopamine concentrations in peripheral venous blood was found to be high and 7.14 0.38% in almost healthy residents of northern territories of the Russian Federation, and significantly higher in patients (59.21 1.7%). There was also a high registration level of elevated concentrations of IL-10 and TNF-α in both practically healthy people and people with oncological diseases. An increase in the frequency of phagocyte deficiency, circulating mature, activated lymphocytes, natural killer and phenotypes of transferrins and IL-2 receptors was observed. In oncological pathology, a high frequency of deficiency of neutrophils, phagocyte activity, NK, mature, activated T-cells, phenotypes of lymphocytes with receptors to transferrin and IL-2 was observed. In oncological pathology, there was a high incidence of deficiency of neutrophils, phagocytic activity, NK, mature, activated T cells, lymphocyte phenotypes with transferrin and IL-2 receptors.

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