Prevalence of social risk factors and its trends in the population of women of reproductive age at the territorial level
https://doi.org/10.25789/YMJ.2023.84.23
Abstract
Introduction. Tumours affecting the reproductive organs are diagnosed in women of fertile age in 20–40% of cases. Therefore, the current situation not only affects the quality and life expectancy of patients, but also leads to a decrease in the reproductive potential of the country. Relevance of Research. The authors’ research aims to obtain new theoretical data regarding the risks of malignant neoplasms in the female genital system correlated with various ratios of risk factors at the territorial level. Materials and Methods. During the initial research stage, the authors employed the analytical method to gather data on risk factors for oncological malignancies identified through content analysis of both domestic and foreign literature sources. During the second research stage, data were collected regarding the incidence of cancer risk factors classified as social and hygienic factors. The data were collected retrospectively for the period of 1995–2020 (n = 36935). The data processing programme comprised the calculation of the prevalence rate of the risk of malignant neoplasms of the reproductive system in women of reproductive age. Research methodical specifics involved constructing parallel chronograms of each cancer risk factor and new onsets of malignant cancer diseases broken down by years of the research period. These data were used as evidence of effectiveness of cancer risk management procedures within the territory. Conclusion. The data obtained bolster the correlation between malignant reproductive diseases in women and social and hygienic risk factors. This substantiates the suggestion to incorporate such risk factors as maternal smoking, late first pregnancy and maternal age over 40 years, early sexual activity and large number of sexual partners in the set of indicators for assessing the risk burden in the territory
About the Authors
I. P. AminodovaRussian Federation
Aminodova Izabella P. – PhD, leading researcher, Department of Lifestyle and Population Health Protection; Assistant Professor, Department of Obstetrics and Gynecology, Faculty of Postgraduate
Education; research fellow
T. P. Vasilieva
Russian Federation
Vasilieva Tatyana P. – MD, Professor of the Department of Lifestyle and Population Health Protection
S. V. Russkikh
Russian Federation
Russkikh Sergey V. – PhD, leading researcher, Department of Lifestyle and Public Health Protection; visiting lecturer, Faculty of Social Sciences, Department of Policy and Management
L. N. Afanasyeva
Russian Federation
Afanasyeva Lena N. – Candidate of Medical Sciences, Associate Professor
M. D. Vasiliev
Russian Federation
Vasiliev Mikhail D. – PhD, researcher, Department of Lifestyle Studies and Population Health Protection
References
1. Aminodova I.P., Lapochkina N.P. Complex therapy and rehabilitation of patients with combined pathology of mammary glands and cervical dysplasia. Tumors of the female reproductive system. 2014;(4):68-70 doi: https://doi.org/10.17650/1994-4098-2014-0-4-68-70
2. Burchakov D.V. New and modifiable risk factors of breast diseases. Effective pharmacotherapy. Obstetrics and Gynecology. 2017; 2:22-27
3. Volobuev, A.I. Results of examination of women with combined benign hyperplastic processes of mammary glands and genital organs / A.I. Volobuev //Akush. i gynec. - 2003. – No. 5. - P. 27.
4. Dicke G.B. Modern approaches to secondary prevention of cervical cancer AiG 2018 No. 4 131-13.doi: https://dx.doi.org/10.18565/aig.2018.4.131-137
5. Dobrenkyi M.N., Dobren'kaya E.M. Risk factors, modern possibilities of prevention and early diagnosis of breast cancer // Fundamental Research. - 2008. – No. 8. - P. 107-108.
6. Dykhno Yu.A., Chernenko O.N. Analysis of breast cancer risk factors in women of the Republic of Khakassia // Siberian Oncological Journal. 2012. No. 6 (54). P. 47-51.
7. Kachalina T. S. Oncorrhizae of endometriosis. // Remedium Privolzhye. - 2017. – No. 3. - P. 21
8. Kovalenko I.M. Berstein L.M. Diabetes mellitus as a modifier of the course of tumors of the female reproductive sphere // Vopr.Onkol. 2014. Т. 60(1). P. 25-31.
9. Belokrinitskaya T.E., Frolova I.I., Tarbaeva D.A., Glotova E.Y., Zolotaryova A.A., Maltseva T.V. Confounding factors of papillomavirus infection and cervical dysplasia in young women. Doctor.ru 2015;14(115): 7-12
10. Babaeva N.A., Ashrafyan L.A., Antonova I.B., Aleshikova O.I., Ivashina S.V. Role of hormonal disorders in carcinogenesis of tumors of the female reproductive system. Obstetrics and Gynecology. Oncogynecology. No. 1. 2017. P.76-82.
11. Bayramova G.R., Baranov I.I., Ezhova L.S., Trofimov D.Yu., Priputnevich T.V., Amirkhanyan A.S., Starinskaya A.M. Squamous cell intraepithelial lesions of the cervix: opportunities for early diagnosis and management tactics for patients // Doctor.Ru. 2019. No. 11 (166). P. 61-67. DOI: 10.31550/1727-2378-2019-166-11-61-67
12. Bebneva T.N., Muizhnek E.L., Rogovskaya S.I., Kiselev V.I., Ashrafyan L.I.I., Kiselev V.I.I., Ashrafyan L.A. Pathogenetic treatment of neoplastic processes of the cervix: new approaches. Doctor.ru. 2016; 3(120): 9-14.
13. Makimbetov E.K., Salihar R.I., Tumanbaev A.M., Toktanalieva A.N., Kerimov A.D. Epidemiology of cancer in the world // Modern Problems of Science and Education. 2020. – No. 2. - P.168. doi: 10.17513/spno.29718
14. Maksimov S.Y., Huseynov K.D., Kosnikov A.G. Risk factors of malignant neoplasms of reproductive system organs of women. Voprosy Onkologii. 2003; 49 (4): 496-501.
15. Practical recommendations on drug treatment of uterine corpus cancer and uterine sarcomas / Nechushkina V.M. [et al.]. Malignant tumors: RUSSCO Practical Recommendations #3s2, 2022 (vol. 12). 260–275. doi: 10.18027/2224-5057-2021-11-3s2-14
16. Parokonnaya A. A., Nechushkin M. I., Kampova-Polevaya E. B., Lyubchenko L. N. Breast cancer and the program of in vitro fertilization // Tumors of the female reproductive system. 2008. No. 4.doi: https://doi.org/10.17650/1994-4098-2008-0-4-52-56
17. Pisareva L.F., Melnik A.A., Odintsova I.N., Martynova N.A. Cancer of reproductive organs: epidemiology, risk factors // Siberian Oncological Journal. 2003. No.1. P.56-71
18. The state of oncologic aid to the Russian population in 2020. Under the editorship of A.D. Kaprin, V.V. Starinsky, A.O. Shakhzadova - M.: P.A. Herzen MNIOI - branch of FGBU "NMRC Radiology" of the Ministry of Health of Russia, 2021. - Ill. - 239 с.
19. The state of oncologic aid to the Russian population in 2021. Under the editorship of A.D. Kaprin, V.V. Starinsky, A.O. Shakhzadova - M.: P.A. Herzen MNIOI - branch of FGBU "NMRC Radiology" of the Ministry of Health of Russia, 2022. - Ill. - 239 p.
20. Epidemiology and screening of breast cancer / Semiglazov V.F [et al.] // Issues in Oncology. 2017; 3(63): 375-384.doi: https://doi.org/10.37469/0507-3758-2017-63-3-375-384
21. Althuis M.D. Breast cancers among very young premenopausal women (United States) / Althuis M.D., Brogan D.D., Coates R.J., Daling J.R., Gammon M.D., Malone K.E., et al. // Cancer Causes Control. 2003:151–60. doi: 10.1023/a:1023006000760
22. Alvarado-Cabrero I., Rodríguez-Gómez A., Castelan-Pedraza J., Valencia-Cedillo R. Metastatic ovarian tumors: a clinicopathologic study of 150 cases. Anal Quant Cytopathol Histpathol 2013 Oct;35(5):241–8. DOI: 10.1109/chicc.2006.4347343. PMID: 24282903
23. Andersen ZJ, Jørgensen JT, Grøn R, Brauner EV, Lynge E. Active smoking and risk of breast cancer in a Danish nurse cohort study. // BMC Cancer. 2017 Aug 22;17(1):556. doi: 10.1186/s12885-017-3546-4.
24. Carey L. A. Race, breast cancer subtypes, and survival in the Carolina Breast Cancer Study Carey, L. A., Perou, C. M., Livasy, C. A.. 2006; 295 (21): 2492-2502. doi: 10.1001/jama.295.21.2492.
25. Chen Y., Liu L., Zhou Q. Body mass index had different effects on premenopausal and postmenopausal breast cancer risks: a dose-response metaanalysis with 3 318 796 subjects from 31 cohort studies. BMC Public Health 2017;17(1):936–47. PMID: 29216920. DOI: 10.1186/s12889-017-4953-9.
26. Collaborative Group on Hormonal Factors in Breast Cancer. Menarche, menopause, and breast cancer risk: individual participant meta-analysis, including 118,964 women with breast cancer from 117 epidemiological studies. Lancet Oncol. 2012; 13 (11): 1141-1151. doi: 10.1016/S1470-2045(12)70425-4
27. Committee on Gynecologic Practice, American College of Obstetricians and Gynecologists. ACOG committee opinion. Induced abortion and breast cancer risk. Number 285, August 2003. Int J Gynaecol Obstet. 2003; 83(2):233-5. doi: 10.1016/s0020-7292(03)00411-9. PMID: 14631935.
28. Fang H.F., Miao N.F., Chen C.D., Sithole T., Chung M. Risk of cancer in patients with insomnia, parasomnia, and obstructive sleep apnea: a nationwide nested case-control study // J. Cancer. 2015; 6 (1): 1140–1147. doi: 10.7150/jca.12490
29. Guerriero S., Alcazar J.L., Pascual M.A. Preoperative diagnosis of metastatic ovarian cancer is related to origin of primary tumor. Ultrasound Obstet Gynecol 2012;39(5):581–6. DOI: 10.1002/uog.10120. PMID: 21998039
30. Hamajima N., Hirose K., Tajima K. et al. Alcohol, tobacco and breast cancer – collaborative reanalysis of individual data from 53 epidemiological studies, including 58,515 women with breast cancer and 95,067 women with out the disease // Br. J. Cancer. 2002; 87:1234-1245. doi: 10.1038/sj.bjc.6600596
31. Islam T., Matsuo K., Ito H. Reproductive and hormonal risk factors for luminal, HER2-overexpressing, and triple-negative breast cancer in Japanese women // Ann. Oncol. 2012; 23 (9): 2435-2441. doi: 10.1093/annonc/mdr613.
32. Lacey J.V. Jr., Kreimer A.R., Buys S.S. Breast cancer epidemiology according to recognized breast cancer risk factors in Prostate, Lung, Colorectal and Ovarian (PLCO) Cancer Screening Trial Cohort // BMC Cancer. 2009; 9:84. doi: 10.1186/1471-2407-9-84
33. Pappo I., Lerner-Geva L., Halevy A., Olmer L., Friedel S., Raziel A., Schachter M., RonEl R. The Possible Association between IVF and Breast Cancer Incidence. Ann Surg Oncol 2008;15(4):1048—55. doi: 10.1245/s10434-007-9800-2
34. Patterson R. E. Medical comorbidities predict mortality in women with a history of early stage breast cancer [Breast cancer research and treatment] / Patterson, R. E., Flatt, S. W., Saquib, N. 2010;122 (3): 859-865. doi: 10.1007/s10549-010-0732-3
35. Singlebaru K.W., Gapstur S.M. Alcohol and breast cancer: review of epidemiologic and experimental evidence and potential mechanisms. JAMA 2001;286(17): 2143—51. 14.
36. Sternfeld B. Physical activity and risk of recurrence and mortality in breast cancer survivors: findings from the LACE study [Cancer Epidemiology and Prevention Biomarkers] / Sternfeld, B., Weltzien, E., Quesenberry, C. P. 2009; 18 (1): 87- 95. doi: 10.1158/1055-9965.EPI-08-0595
37. Vachon C., Cerhan J.R., Vierkant R.A., Sellers T.A. Investigation of an interaction of alcohol intake and family history on breast cancer risk in the Minnesota Breast Cancer Family Study. Cancer 2001;92(2): 240—8. doi: 10.1002/10970142(20010715)92:2<240::aid-cncr1315>3.0.co;2-i
38. Walker S, Hamilton W. Risk of cervical cancer in symptomatic women aged ≥40 in primary care: A case-control study using electronic records. Eur J Cancer Care (Engl). 2017. doi: 10.1111/ecc.12706
39. Yada-Hashimoto N., Yamamoto T., Kamiura S. Metastatic ovarian tumors: a review of 64 cases. Gynecol Oncol 2013;89(2):314–7. DOI: 10.1016/s0090–8258(03)00075–1. PMID: 12713997
40. 3Yu H.C., Lin C.Y., Chang W.C. et al. Increased association between endometriosis and endometrial cancer: a nationwide population-based retrospective cohort study / / Int. J. Gynecol. Cancer. 2015; 25 (3): 447-452. doi: 10.1097/IGC.0000000000000384
Review
For citations:
Aminodova I.P., Vasilieva T.P., Russkikh S.V., Afanasyeva L.N., Vasiliev M.D. Prevalence of social risk factors and its trends in the population of women of reproductive age at the territorial level. Yakut Medical Journal. 2023;(4):94-100. https://doi.org/10.25789/YMJ.2023.84.23