The expression of surface markers on peripheral blood lymphocytes in patients in Yakutia
Abstract
A research objective was an assessment of an expression of superficial markers of lymphocytes in patients with IHD of a various form depending on ethnicity. The received results of the comparative analysis depending on IHD form allow to confirm that destabilization of IHD is characterized by increase of an expression of CD19 + (B-lymphocytes), activation markers of CD25 + (a receptor to IL-2) and CD71 + (a trancferrine receptor), and also molecules of intercellular adhesion of CD54 + (ICAM-1). At unstable angina in persons of native nationality signs of deficiency of the Tcellular link (T-lymphocytes, T-helper), and also significant increase of expression СD11b + (integrine) in comparison with persons of non-native nationality are revealed.
About the Authors
A. S. Golderova
ЯНЦ КМП СО РАМН
Russian Federation
Russian Federation
Ajtalina Semenovna Golderova - the candidate of medical sciences, the main research assistant of department of studying of mechanisms of acclimatization
I. N. Nikolaeva
ЯНЦ КМП СО РАМН
Russian Federation
Russian Federation
Irina Nikolaevna Nikolaeva - the senior research assistant of laboratory of immunology
V. A. Kozlov
Russian Academy of Medical Science;
Siberian branch of the Russian Academy of Medical Science
Russian Federation
Russian Federation
Vladimir Aleksandrovich Kozlov - the doctor of medical sciences, the academician;
the director of Scientific research institute of clinical immunology
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Review
For citations:
Golderova A.S., Nikolaeva I.N., Kozlov V.A. The expression of surface markers on peripheral blood lymphocytes in patients in Yakutia. Yakut Medical Journal. 2012;(3):59-62.
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