Biochemical method for determining the readiness of burn wounds for autodermoplasty
https://doi.org/10.25789/YMJ.2024.88.08
Abstract
This article is devoted to the results of studying wound discharge from the surface of burn wounds for the purpose of develop a method for determining their readiness for autodermoplasty. The indicators of total protein, fibrinogen, and the degree of bacterial contamination from the wound surface during sowing were studied in the wound discharge. Based on the obtained results of laboratory studies a dependence of changes in the concentrations of total protein and fibrinogen on the level of bacterial contamination of wounds was established. The data revealed allowed us to develop a method for determining the readiness of the burn wound surface for autodermoplasty. The method makes it possible to make a decision on performing surgical intervention without waiting for bacterial culture data.
About the Authors
E. A. Kchibekov
Астраханский государств. медицин. ун-т
Russian Federation
Russian Federation
K. Yu. Melnikova
Астраханский государств. медицин. ун-т
Russian Federation
Russian Federation
V. A. Zurnadzhyants
Астраханский государств. медицин. ун-т
Russian Federation
Russian Federation
References
1. Abdurakhmanova Z.R. Lipid peroxidation // Collection of scientific articles based on the materials of the X International Scientific and Practical Conference “Topical Issues of Modern Science: Theory, Methodology, Practice, Innovation.” 2023. Vol. 1. Р. 46-51.
2. Belinskaya D.A., Voronina P.A., Goncharov N.V. Integrative role of albumin: evolutionary, biochemical and pathophysiological aspects // Russian Logical Journal named after. THEM. Sechenov. 2021. No. 12(107). P. 1455–1489.
3. Gostishchev V.K. Differentiated approach to the choice of skin-plastic operations for patients with surgical infection // Surgery. Journal named after N.I. Pirogov. 2009. № 12. P. 20–23.
4. Zinoviev E.V., Soloshenko V.V., Kourov A.S., Shapovalov S.G. On the issue of tangential necrectomy in burn surgery (literature review) // Medicо-Biological and Socio-Psychological Problems of Safety in Emergency Situations. 2020. №3. Р. 24-35. https://doi.org/10.25016/2541-7487-2020-0-3-24-35
5. Zinoviev E.V., Soloshenko V.V., Yurova Y.V., Kostyakov D.V., Vagner D.O., Krylov P.K. Lysis/ rejection of split autoderm grafts – solutions // Bulletin of the Russian Military Medical Academy. 2020. Vol. 22. N. 3. P. 194-198. https://doi: 10.17816/brmma50559
6. Infectious complications of burn disease / Kutyavin N.A., Maratkanov M.V., Fatykhova Ch.A., Styazhkina S.N. // Modern science. 2021.№4(2). pp. 50-53.
7. Lipatov K.V., Komarova E.A., Krivikhin D.V. Features of autodermoplasty with a split flap in purulent surgery // Almanac of Clinical Medicine. 2007. No. 16. Р. 96-99.
8. Permeability of a burn scab to water and microorganisms: justification for the timing of necrectomy / Ryabkov M.G. and others // Emergency surgery named after. I.I. Dzhanelidze. Collection of materials from the conference “Current problems of thermal injury”. 2021. No. 1. P.53-54.
9. Fayazov A.D., Tulyaganov D.B., Kamilov U.R., Ruzimuratov D.A. Modern methods of local treatment of burn wounds // Bulletin of emergency medicine. 2019. №1. Vol. 12. Р. 43-47. https://cyberleninka.ru/article/n/sovremennyemetody-mestnogo-lecheniya-ozhogovyh-ran-1
10. Yurova Yu. V. Diagnosis of readiness of granulating burn wounds for free autodermoplasty. Abstract of thesis of Doctor of Medical Sciences. Saint. Petersburg; 2014. 156 p.
11. Yurova Yu.V., Zinoviev E.V. The influence of methods of surgical treatment of burn wounds on the incidence of pathological scars // Emergency surgery named after. I.I. Dzhanelidze. Collection of materials from the conference “Current problems of thermal injury”. 2021. No. 1. P.77-78.
12. Thachil, J. The protective rather than prothrombotic fibrinogen in COVID-19 and other inflammatory states / J. Thachil //J Thromb Haemost. 2020. №18. P. 1849–1852.
Review
For citations:
Kchibekov E.A., Melnikova K.Yu., Zurnadzhyants V.A. Biochemical method for determining the readiness of burn wounds for autodermoplasty. Yakut Medical Journal. 2024;(4):32-34. (In Russ.) https://doi.org/10.25789/YMJ.2024.88.08
Views:
9
Email this article 