Morphological investigations of thyrotropic endocrine cells of rats’ adenohypophysis under experimental immunosuppression
Abstract
The features of structural reorganization of thyrotropic endocrine cells of distal adenohypophysis of rats of puberty at experimental immunosuppression were under study. Immunosuppressive condition was modelled in animals by administration of a cytostatic drug cyclophosphamide.
It was found that the administration of cyclophosphamide to test animals of puberty causes an active response of thyrotropic endocrine cells of anterior pituitary, as evidenced by the development of polymorphic morphological changes, the nature and the severity of which depends on the terms after administration of cytostatic.
About the Author
I. V. Bobrysheva
State Establishment «Lugansk State Medical University»
Russian Federation
Russian Federation
Bobrysheva Inessa Venidiktovna candidate of Medical Sciences, associate professor, dean of Dentistry faculty, associate professor of Histology, Cytology and Embryology Department
1, kv. 50-letiya Oborony Luganska, 91045, Lugansk
+38 095 399 8
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Review
For citations:
Bobrysheva I.V. Morphological investigations of thyrotropic endocrine cells of rats’ adenohypophysis under experimental immunosuppression. Yakut Medical Journal. 2016;(3):21-23.
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