Pathomorphology of regional intrachest lymph nodes at destructive tuberculosis of lungs with account of drug resistance of micobacteries
Abstract
We studied morphological changes in the regional intra chest lymph nodes with drug-resistant fibro-cavernous pulmonary tuberculosis. Macroscopically all groups of lymph nodes were increased in sizes, indurated, with small foci of caseous necrosis. At the microscopic research of regional intra chest lymph nodes on the background of hyperplasia there was sharp narrowing and devastation of a T-zone with atrophy of a significant amount of lymphoid follicles. Thus, in the group with multidrug resistance the width of the paracortical zone is twice less than in the groups with monoresistance and remained constant drug resistance. Its bound with the cortical zone wasn’t determined. The higher rate of pathomorphological changes were observed in the groups with polyresistance and multidrug resistance.
About the Authors
I. Yu. Makarov
Amur State Medical Academy
Russian Federation
Russian Federation
Doctor of med. sciences, professor, Amur State Medical Academy.
Blagoveshchensk, 95, Gorkogo Str., Blagoveshchensk, 675000
E. N. Zhukova
Amur State Medical Academy
Russian Federation
Russian Federation
Blagoveshchensk, 103, Gorkogo Str., Blagoveshchensk, 675000
R. A. Zhdanova
Amur State Medical Academy
Russian Federation
Russian Federation
Blagoveshchensk, 103, Gorkogo Str., Blagoveshchensk, 675000
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Review
For citations:
Makarov I.Yu., Zhukova E.N., Zhdanova R.A. Pathomorphology of regional intrachest lymph nodes at destructive tuberculosis of lungs with account of drug resistance of micobacteries. Yakut Medical Journal. 2015;(2):57-59.
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