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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">ymj</journal-id><journal-title-group><journal-title xml:lang="ru">Якутский медицинский журнал</journal-title><trans-title-group xml:lang="en"><trans-title>Yakut Medical Journal</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">1813-1905</issn><issn pub-type="epub">2312-1017</issn><publisher><publisher-name>ЯНЦ КМП</publisher-name></publisher></journal-meta><article-meta><article-id custom-type="elpub" pub-id-type="custom">ymj-936</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>ОРИГИНАЛЬНЫЕ ИССЛЕДОВАНИЯ</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>ORIGINAL RESEARCH</subject></subj-group></article-categories><title-group><article-title>Показатели гормонального статуса женщин с миомой матки старшего репродуктивного возраста на фоне гормонотерапии</article-title><trans-title-group xml:lang="en"><trans-title>Indicators of the hormonal status of women with uterine fibroids of senior reproductive age on the background of hormone therapy</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Камилова</surname><given-names>Н. М.</given-names></name><name name-style="western" xml:lang="en"><surname>Kamilova</surname><given-names>M. M.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Камилова Нигяр Мир-Наги кызы – д.м.н., проф.</p><p>г. Баку</p></bio><bio xml:lang="en"><p>Kamilova Nigar Mir Nagi, Professor, Doctor of Medical Sciences, Department of “Obstetrics-Gynecology 1”</p><p>Baku city, Tel .: +994503252314</p></bio><email xlink:type="simple">nigar65@mail.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Гаджиева</surname><given-names>И. А.</given-names></name><name name-style="western" xml:lang="en"><surname>Hajiyeva</surname><given-names>I. A.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Гаджиева Илаха Ариф кызы – диссертант кафедры акушерства и гинекологии</p><p>г. Баку</p></bio><bio xml:lang="en"><p>Hajiyeva Ilaha Arif, dissertator, Department of “Obstetrics-Gynecology 1”</p><p>Baku city, Tel .: +994503269841</p></bio><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Султанова</surname><given-names>И. А.</given-names></name><name name-style="western" xml:lang="en"><surname>Sultanova</surname><given-names>I. A.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Султанова Ирада Аладдин кызы – к.м.н., доцент</p><p>г. Баку</p></bio><bio xml:lang="en"><p>Sultanova Irada Aladdin, Associate Professor, PhD, Department of “Obstetrics-Gynecology 1”</p><p>Baku city, Tel .: +994502040090</p></bio><xref ref-type="aff" rid="aff-1"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru"><institution>Азербайджанский медицинский университет</institution><country>Азербайджан</country></aff><aff xml:lang="en"><institution>Azerbaijan Medical University</institution><country>Azerbaijan</country></aff></aff-alternatives><pub-date pub-type="collection"><year>2017</year></pub-date><pub-date pub-type="epub"><day>26</day><month>08</month><year>2025</year></pub-date><volume>0</volume><issue>1</issue><fpage>27</fpage><lpage>29</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Камилова Н.М., Гаджиева И.А., Султанова И.А., 2025</copyright-statement><copyright-year>2025</copyright-year><copyright-holder xml:lang="ru">Камилова Н.М., Гаджиева И.А., Султанова И.А.</copyright-holder><copyright-holder xml:lang="en">Kamilova M.M., Hajiyeva I.A., Sultanova I.A.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://ymj.elpub.ru/jour/article/view/936">https://ymj.elpub.ru/jour/article/view/936</self-uri><abstract><p>Исследовали уровень стероидных и гонадотропных гормонов у женщин старшего репродуктивного возраста для выявления маркеров раннего прогнозирования миомы матки. Для консервативного лечения миомы матки наиболее эффективным препаратом был признан Улипристал ацетат («Эсмия», Венгрия). Углубленное изучение клинико-лабораторных показателей, в том числе гормональных, позволят усовершенствовать тактику ведения пациентов, разработать показания и противопоказания применения данного препарата, повысить их эффективность, разработать алгоритм терапии пациентов с диагнозом миома матки.</p></abstract><trans-abstract xml:lang="en"><p>The authors investigated the level of steroid and gonadotropin-releasing hormones in women of older reproductive age to identify early markers predicting uterine fibroids. We have recognized Ulipristal acetate («Esmiya», Hungary) as the most effective drug for the conservative treatment of uterine fibroids. An in-depth study of the clinical and laboratory, including hormonal parameters will improve the tactics of directing patients, develop indications and contraindications for the use of the drug, increase their efficiency, develop an algorithm for the treatment of patients with a diagnosis uterine fibroids.</p></trans-abstract><kwd-group xml:lang="ru"><kwd>миома матки</kwd><kwd>гормональные показатели</kwd><kwd>Улипристал ацетат (Эсмия)</kwd><kwd>гормонотерапия</kwd></kwd-group><kwd-group xml:lang="en"><kwd>uterine fibroids</kwd><kwd>hormonal parameters</kwd><kwd>Ulipristal acetate</kwd><kwd>hormone therapy</kwd></kwd-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Буянова С.Н. Современные представления об этиологии, патогенезе и морфогенезе миомы матки / С.Н. Буянова, М.В. Мгелиашвили, С.А. 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