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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">ymj</journal-id><journal-title-group><journal-title xml:lang="ru">Якутский медицинский журнал</journal-title><trans-title-group xml:lang="en"><trans-title>Yakut Medical Journal</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">1813-1905</issn><issn pub-type="epub">2312-1017</issn><publisher><publisher-name>ЯНЦ КМП</publisher-name></publisher></journal-meta><article-meta><article-id custom-type="elpub" pub-id-type="custom">ymj-933</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>АРКТИЧЕСКАЯ МЕДИЦИНА</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>ARCTIC MEDICINE</subject></subj-group></article-categories><title-group><article-title>Особенности клинико-иммунологического течения острой пневмонии у детей</article-title><trans-title-group xml:lang="en"><trans-title>Features of clinical and immunological course of acute pneumonia in children</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Иванова</surname><given-names>О. Н.</given-names></name><name name-style="western" xml:lang="en"><surname>Ivanova</surname><given-names>O. N.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Ольга Николаевна Иванова, д. м. н, проф.</p><p>МИ</p><p>Якутск</p></bio><bio xml:lang="en"><p>Yakutsk</p></bio><email xlink:type="simple">olgadoctor@list.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Тогуллаева</surname><given-names>М. А.</given-names></name><name name-style="western" xml:lang="en"><surname>Togulayeva</surname><given-names>M. A.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Матрена Афанасьевна Тогуллаева, зам. гл. врача по КЭР</p><p>Якутск</p></bio><bio xml:lang="en"><p>Yakutsk</p></bio><xref ref-type="aff" rid="aff-2"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Гольдерова</surname><given-names>А. C.</given-names></name><name name-style="western" xml:lang="en"><surname>Golderova</surname><given-names>A. C.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Айталина Семеновна Гольдерова, д. м. н., гл. н. с., руковод. отдела</p><p>Якутск</p></bio><bio xml:lang="en"><p>Yakutsk</p></bio><email xlink:type="simple">hoto68@mail.ru</email><xref ref-type="aff" rid="aff-3"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru"><institution>СВФУ им. М.К. Аммосова</institution><country>Россия</country></aff><aff xml:lang="en"><institution>North-Eastern Federal University named after M.K. Ammosov</institution><country>Russian Federation</country></aff></aff-alternatives><aff-alternatives id="aff-2"><aff xml:lang="ru"><institution>ДГКБ № 2</institution><country>Россия</country></aff><aff xml:lang="en"><institution>DGKB No. 2</institution><country>Russian Federation</country></aff></aff-alternatives><aff-alternatives id="aff-3"><aff xml:lang="ru"><institution>ЯНЦ КМП</institution><country>Россия</country></aff><aff xml:lang="en"><institution>YaNC KMP</institution><country>Russian Federation</country></aff></aff-alternatives><pub-date pub-type="collection"><year>2017</year></pub-date><pub-date pub-type="epub"><day>23</day><month>08</month><year>2025</year></pub-date><volume>0</volume><issue>2</issue><fpage>31</fpage><lpage>32</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Иванова О.Н., Тогуллаева М.А., Гольдерова А.C., 2025</copyright-statement><copyright-year>2025</copyright-year><copyright-holder xml:lang="ru">Иванова О.Н., Тогуллаева М.А., Гольдерова А.C.</copyright-holder><copyright-holder xml:lang="en">Ivanova O.N., Togulayeva M.A., Golderova A.C.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://ymj.elpub.ru/jour/article/view/933">https://ymj.elpub.ru/jour/article/view/933</self-uri><abstract><p>   Проведено изучение этиологических факторов острых пневмоний (ОП), а также изменений иммунного статуса у детей с ОП. Выявлено, что наиболее частый возбудитель пневмоний – Streptococc pneumonia, второе место по частоте занимает Clebciella pneumonia, третье – комбинация C. pneumonia, Pseudomonas aureginosa, Chlamidia pneumonia. При анализе изменений иммунного статуса у детей с острыми пневмониями в сравнении с группой здоровых детей выявлено наибольшее снижение показателей Т-клеточного звена (СD3+, СD4+, СD16+), компонентов комплемента С3 и С4, В-клеточного звена СD22+ .</p></abstract><trans-abstract xml:lang="en"><p>   The article dwells on the study of the etiological factors of acute pneumonia in children, as well as changes in the immune status. It was revealed that the most frequent causative agent of pneumonia is Streptococci pneumonia; the second most frequent is Klebciella pneumonia, followed by a combination of C. pneumonia, Pseudomonas aureginosa, Chlamidia pneumonia. At analyzing the changes in the immune status in children with acute pneumonia, in comparison with the group of healthy children, the greatest decrease in T-cell (CD3 +, CD4 +, CD16 +), complement components C3 and C4, B-cell link of CD22 + was found.</p></trans-abstract><kwd-group xml:lang="ru"><kwd>пневмония</kwd><kwd>стрептококк</kwd><kwd>микробиологическое исследование</kwd><kwd>клебсиелла</kwd></kwd-group><kwd-group xml:lang="en"><kwd>pneumonia</kwd><kwd>streptococcus</kwd><kwd>microbiological examination</kwd><kwd>Klebciella</kwd></kwd-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Болезни органов дыхания у детей / Под ред. С.В. Рачинского, В.К. Таточенко. – М.: Медицина, 2007. – 496 с.</mixed-citation><mixed-citation xml:lang="en">Diseases of the respiratory system in children / ed. by S.V. Raczynski, V.K. Tatochenko – M.: Medicine, 2007. – 496 p.</mixed-citation></citation-alternatives></ref><ref id="cit2"><label>2</label><citation-alternatives><mixed-citation xml:lang="ru">Вельтищев Ю.Е. Иммунодефицитные состояния / Ю.Е. Вельтищев // Прикладная иммунология / под ред. А.А. Сохина. – Киев: Здоровье, 2014. – С. 76-105.</mixed-citation><mixed-citation xml:lang="en">Vel’tishhev Ju. E. Immunodeficiency / Ju.E. Vel’tishhev //Applied immunology ed. by A.A. Sokhin. – Kiev: Health, 2014. –76-105 p.</mixed-citation></citation-alternatives></ref><ref id="cit3"><label>3</label><citation-alternatives><mixed-citation xml:lang="ru">Вельтищев Ю.Е. Острые пневмонии у детей / Ю.Е. Вельтищев. – М.: Медицина, 2015.</mixed-citation><mixed-citation xml:lang="en">Veltischev Yu.A. Acute pneumonia in children / Yu.A. Veltischev. – M: Medicine, 2015.</mixed-citation></citation-alternatives></ref><ref id="cit4"><label>4</label><citation-alternatives><mixed-citation xml:lang="ru">Гавалов С.М. Острые пневмонии у детей / С.М. Гавалов. – Новосибирск: Изд-во Новосиб. ун-та, 2014.</mixed-citation><mixed-citation xml:lang="en">Gavalov S.M. Acute pneumonia in children / S.M. Gavalov. – Novosibirsk: Publishing house of Novosibirsk university, 2014.</mixed-citation></citation-alternatives></ref></ref-list><fn-group><fn fn-type="conflict"><p>The authors declare that there are no conflicts of interest present.</p></fn></fn-group></back></article>
