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<article article-type="conference-paper" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">ymj</journal-id><journal-title-group><journal-title xml:lang="ru">Якутский медицинский журнал</journal-title><trans-title-group xml:lang="en"><trans-title>Yakut Medical Journal</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">1813-1905</issn><issn pub-type="epub">2312-1017</issn><publisher><publisher-name>ЯНЦ КМП</publisher-name></publisher></journal-meta><article-meta><article-id custom-type="elpub" pub-id-type="custom">ymj-929</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>Материалы конференции «Актуальные проблемы педиатрии», посвященной 25-летию РБ№1- Национальный цеyтр медицины МЗ РС(Я)</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>Materials of the conference “Actual problems of pediatrics”, dedicated to the 25th anniversary of RH№1 - the National Center of Medicine of the Health Ministry of the RS (Ya)</subject></subj-group></article-categories><title-group><article-title>Первичный иммунодефицит у больного с бронхиальной астмой</article-title><trans-title-group xml:lang="en"><trans-title>Primary immunodeficiency in a patient with bronchial asthma</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Артамонова</surname><given-names>С. Ю.</given-names></name><name name-style="western" xml:lang="en"><surname>Artamonova</surname><given-names>S. U.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Артамонова Саргылана Юрьевна – к.м.н., доцент</p></bio><bio xml:lang="en"><p>Sargylana Urievna Artamonova, MD, Associate Professor of the Department Propaedeutics childhood diseases</p><p>89246635471</p></bio><email xlink:type="simple">sarartam@mail.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Ханды</surname><given-names>М. В.</given-names></name><name name-style="western" xml:lang="en"><surname>Handy</surname><given-names>M. V.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Ханды Мария Васильевна – д.м.н., проф.</p></bio><bio xml:lang="en"><p>Maria Vasilievna Khandy, MD, Professor of the Department Propaedeutics childhood diseases</p><p>89142331281</p></bio><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Николаева</surname><given-names>Л. Е.</given-names></name><name name-style="western" xml:lang="en"><surname>Nikolaeva</surname><given-names>L. E.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Николаева Лена Егоровна – зав. отделением пульмонологии</p></bio><bio xml:lang="en"><p>Lena Egorovna Nikolaeva, head of the Department of pulmonology</p><p>89841169521</p></bio><xref ref-type="aff" rid="aff-2"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Москвина</surname><given-names>А. И.</given-names></name><name name-style="western" xml:lang="en"><surname>Moskvina</surname><given-names>A. I.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Москвина Алена Ивановна – врач пульмонолог</p></bio><bio xml:lang="en"><p>Alena I. Moskvina, Doctor pulmonologist of Pulmonology Departmentin</p><p>+79841169521</p></bio><xref ref-type="aff" rid="aff-2"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru"><institution>МИ СВФУ им. М. К. Аммосова</institution><country>Россия</country></aff><aff xml:lang="en"><institution>MI NEFU</institution><country>Russian Federation</country></aff></aff-alternatives><aff-alternatives id="aff-2"><aff xml:lang="ru"><institution>Педиатрический центр РБ №1 - Национальный центр медицины</institution><country>Россия</country></aff><aff xml:lang="en"><institution>Pediatric Center “Republican hospital №1 – National Centre of Medicine»</institution><country>Russian Federation</country></aff></aff-alternatives><pub-date pub-type="collection"><year>2017</year></pub-date><pub-date pub-type="epub"><day>26</day><month>08</month><year>2025</year></pub-date><volume>0</volume><issue>1</issue><fpage>18</fpage><lpage>20</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Артамонова С.Ю., Ханды М.В., Николаева Л.Е., Москвина А.И., 2025</copyright-statement><copyright-year>2025</copyright-year><copyright-holder xml:lang="ru">Артамонова С.Ю., Ханды М.В., Николаева Л.Е., Москвина А.И.</copyright-holder><copyright-holder xml:lang="en">Artamonova S.U., Handy M.V., Nikolaeva L.E., Moskvina A.I.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://ymj.elpub.ru/jour/article/view/929">https://ymj.elpub.ru/jour/article/view/929</self-uri><abstract><p>Описывается случай первичного иммунодефицита у ребёнка с бронхиальной астмой. Первичные иммунодефициты относятся к редким болезням, поэтому осведомленность о данной патологии недостаточная, что приводит к несвоевременной диагностике и неадекватному лечению больных, страдающих первичными иммунодефицитами. Аллергические заболевания нередко доминируют в клинической картине иммунодефицитных состояний.</p></abstract><trans-abstract xml:lang="en"><p>The article is devoted to an actual problem of primary immunodeficiencies. Primary immunodeficiencies are rare diseases, and awareness of this pathological condition is not enough. Itleads to late diagnosis and inadequate treatment of patients suffering from primary immunodeficiency.</p><p>Allergic diseases often dominate clinical picture of immunodeficiency states. There is a case’s descriptionof primary immunodeficiency in a child with asthma.</p></trans-abstract><kwd-group xml:lang="ru"><kwd>бронхиальная астма</kwd><kwd>первичный иммунодефицит</kwd><kwd>аллергические проявления</kwd></kwd-group><kwd-group xml:lang="en"><kwd>bronchialasthma</kwd><kwd>primary immunodeficiency</kwd><kwd>clinical case</kwd></kwd-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Кондратенко И.В. Первичные иммунодефициты / И.В. Кондратенко //Медицинская иммунология. – 2005. – Т.7, № 5-6. – С. 469.</mixed-citation><mixed-citation xml:lang="en">Kondratenko I.V. Primary immunodeficiencies / I.V. Kondratenko. -2005. – V. 7.– № 5-6. – P.469.</mixed-citation></citation-alternatives></ref><ref id="cit2"><label>2</label><citation-alternatives><mixed-citation xml:lang="ru">Латышева Е.А. Первичные иммунодефициты: состояние проблемы на сегодняшний день. 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