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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">ymj</journal-id><journal-title-group><journal-title xml:lang="ru">Якутский медицинский журнал</journal-title><trans-title-group xml:lang="en"><trans-title>Yakut Medical Journal</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">1813-1905</issn><issn pub-type="epub">2312-1017</issn><publisher><publisher-name>ЯНЦ КМП</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="doi">10.25789/YMJ.2019.66.06</article-id><article-id custom-type="elpub" pub-id-type="custom">ymj-910</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>ОРИГИНАЛЬНЫЕ ИССЛЕДОВАНИЯ</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>ORIGINAL RESEARCH</subject></subj-group></article-categories><title-group><article-title>Интенсивность пероксидации у жителей Якутии в зонах с высокой онкозаболеваемостью</article-title><trans-title-group xml:lang="en"><trans-title>Peroxidation intensity in Yakutia residents in zones with a high rate of oncological morbidity</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Олесова</surname><given-names>Л. Д.</given-names></name><name name-style="western" xml:lang="en"><surname>Olesova</surname><given-names>L. D.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Олесова Любовь Дыгыновна ‒ к.б.н., в.н.с. ‒ руковод. лаб.</p></bio><bio xml:lang="en"><p>Olesova Lyubov Dygynovna - Ph.D., leading researcher - head of the laboratory of Biochemistry</p><p>677010, Yakutsk, Sergelyakhskoye Highway, 4 km, Republic Sakha (Yakutia)</p></bio><email xlink:type="simple">oles59@mail.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Охлопкова</surname><given-names>Е. Д.</given-names></name><name name-style="western" xml:lang="en"><surname>Okhlopkova</surname><given-names>E. D.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Охлопкова Елена Дмитриевна ‒ к.б.н., в.н.с. ‒ руковод. лаб.</p></bio><bio xml:lang="en"><p>Okhlopkova Elena Dmitrievna - Ph.D., leading researcher - head of Immunology Laboratory</p><p>677010, Yakutsk, Sergelyakhskoye Highway, 4 km, Republic Sakha (Yakutia)</p></bio><email xlink:type="simple">elena_ohlopkova@mail.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Григорьева</surname><given-names>А. А.</given-names></name><name name-style="western" xml:lang="en"><surname>Grigoryeva</surname><given-names>A. A.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Григорьева Анастасия Анатольевна ‒ н.с.</p></bio><bio xml:lang="en"><p>Grigoryeva Anastasia Anatolyevna - a research fellow at the laboratory of biochemistry</p><p>677010, Yakutsk, Sergelyakhskoye Highway, 4 km, Republic Sakha (Yakutia)</p></bio><email xlink:type="simple">nastiagrigoryeva@gmail.com</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Семенова</surname><given-names>Е. И.</given-names></name><name name-style="western" xml:lang="en"><surname>Semenova</surname><given-names>E. I.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Семенова Евгения Ивановна ‒ к.б.н., с.н.с.</p></bio><bio xml:lang="en"><p>Semenova Evgenia Ivanovna - Candidate of Biological Sciences, Senior Researcher at the laboratory of biochemistry</p><p>677010, Yakutsk, Sergelyakhskoye Highway, 4 km, Republic Sakha (Yakutia)</p></bio><email xlink:type="simple">kunsuntar@mail.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Кривошапкина</surname><given-names>З. Н.</given-names></name><name name-style="western" xml:lang="en"><surname>Krivoshapkina</surname><given-names>Z. N.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Кривошапкина Зоя Николаевна ‒ к.б.н., с.н.с.</p></bio><bio xml:lang="en"><p>Krivoshapkina Zoya Nikolaevna - Ph.D., senior research fellow at the laboratory of biochemistry</p><p>677010, Yakutsk, Sergelyakhskoye Highway, 4 km, Republic Sakha (Yakutia)</p></bio><email xlink:type="simple">zoyakriv@mail.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Константинова</surname><given-names>Л. И.</given-names></name><name name-style="western" xml:lang="en"><surname>Konstantinova</surname><given-names>L. I.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Константинова Лена Ивановна ‒ м.н.с.</p></bio><bio xml:lang="en"><p>Konstantinova Lena Ivanovna - Researcher at the Laboratory of biochemistry</p><p>677010, Yakutsk, Sergelyakhskoye Highway, 4 km, Republic Sakha (Yakutia)</p></bio><email xlink:type="simple">konstanta.l@mail.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Ефремова</surname><given-names>А. В.</given-names></name><name name-style="western" xml:lang="en"><surname>Efremova</surname><given-names>A. V.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Ефремова Аграфена Владимировна ‒ к.б.н., с.н.с.</p></bio><bio xml:lang="en"><p>Efremova Agrafena Vladimirovna - Ph.D., Senior Researcher at the laboratory of biochemistry</p><p>677010, Yakutsk, Sergelyakhskoye Highway, 4 km, Republic Sakha (Yakutia)</p></bio><email xlink:type="simple">a.efremova01@mail.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Яковлева</surname><given-names>А. И.</given-names></name><name name-style="western" xml:lang="en"><surname>Yakovleva</surname><given-names>A. I.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Яковлева Александра Ивановна ‒ н.с.</p></bio><bio xml:lang="en"><p>Yakovleva Alexandra Ivanovna - a research fellow at the laboratory of biochemistry</p><p>677010, Yakutsk, Sergelyakhskoye Highway, 4 km, Republic Sakha (Yakutia)</p></bio><email xlink:type="simple">sashyak@mail.ru</email><xref ref-type="aff" rid="aff-1"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru"><institution>Якутский НЦ комплексных медицинских проблем</institution><country>Россия</country></aff><aff xml:lang="en"><institution>Federal State Budget Scientific Institution «Yakut Science Center of Complex Medical Problems»</institution><country>Russian Federation</country></aff></aff-alternatives><pub-date pub-type="collection"><year>2019</year></pub-date><pub-date pub-type="epub"><day>22</day><month>08</month><year>2025</year></pub-date><volume>0</volume><issue>2</issue><fpage>23</fpage><lpage>25</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Олесова Л.Д., Охлопкова Е.Д., Григорьева А.А., Семенова Е.И., Кривошапкина З.Н., Константинова Л.И., Ефремова А.В., Яковлева А.И., 2025</copyright-statement><copyright-year>2025</copyright-year><copyright-holder xml:lang="ru">Олесова Л.Д., Охлопкова Е.Д., Григорьева А.А., Семенова Е.И., Кривошапкина З.Н., Константинова Л.И., Ефремова А.В., Яковлева А.И.</copyright-holder><copyright-holder xml:lang="en">Olesova L.D., Okhlopkova E.D., Grigoryeva A.A., Semenova E.I., Krivoshapkina Z.N., Konstantinova L.I., Efremova A.V., Yakovleva A.I.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://ymj.elpub.ru/jour/article/view/910">https://ymj.elpub.ru/jour/article/view/910</self-uri><abstract><p>Проведен анализ особенностей свободнорадикальных процессов у жителей Якутии в двух зонах с высоким показателем онкозаболеваемости. Установлена интенсификация перекисного окисления липидов у жителей Южной зоны, где наблюдается высокий уровень новообразований.</p></abstract><trans-abstract xml:lang="en"><p>The analysis of the peculiarities of free-radical processes in Yakutia residents in two zones with a high rate of oncological morbidity was carried out. The intensification of lipid peroxidation in residents of the southern zone, where a high incidence of neoplasms, was established.</p></trans-abstract><kwd-group xml:lang="ru"><kwd>перекисное окисление липидов</kwd><kwd>антиоксидантная защита</kwd><kwd>дизадаптация</kwd><kwd>онкозаболеваемость</kwd></kwd-group><kwd-group xml:lang="en"><kwd>lipid peroxidation</kwd><kwd>antioxidant protection</kwd><kwd>disadaptation</kwd><kwd>cancer incidence</kwd></kwd-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Владимиров Ю.А. 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