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<article article-type="conference-paper" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">ymj</journal-id><journal-title-group><journal-title xml:lang="ru">Якутский медицинский журнал</journal-title><trans-title-group xml:lang="en"><trans-title>Yakut Medical Journal</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">1813-1905</issn><issn pub-type="epub">2312-1017</issn><publisher><publisher-name>ЯНЦ КМП</publisher-name></publisher></journal-meta><article-meta><article-id custom-type="elpub" pub-id-type="custom">ymj-889</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>Материалы конференции «Актуальные проблемы педиатрии», посвященной 25-летию РБ№1- Национальный цеyтр медицины МЗ РС(Я)</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>Materials of the conference “Actual problems of pediatrics”, dedicated to the 25th anniversary of RH№1 - the National Center of Medicine of the Health Ministry of the RS (Ya)</subject></subj-group></article-categories><title-group><article-title>Цитомегаловирусная инфекция у детей</article-title><trans-title-group xml:lang="en"><trans-title>Cytomegalovirus infection in children</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Иванова</surname><given-names>О. Н.</given-names></name><name name-style="western" xml:lang="en"><surname>Ivanova</surname><given-names>O. N.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Иванова Ольга Николаевна – д.м.н., проф.</p></bio><bio xml:lang="en"><p>Ivanova Olga Nikolaevna - MD, Professor, Department of Pediatrics and Pediatric Surgery</p><p>Yakutsk, ul. Oiunsky, 27, tel (4112) 36-30-46 (fax)</p></bio><email xlink:type="simple">olgadoctor@list.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Гольдерова</surname><given-names>А. С.</given-names></name><name name-style="western" xml:lang="en"><surname>Golderova</surname><given-names>A. N.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Гольдерова Айталина Семеновна – д.м.н., гл.н.с.- руковод. отдела </p></bio><bio xml:lang="en"><p>Golderova Aytalina Semenovna - MD, senior researcher at the Department of studying adaptation mechanisms</p></bio><email xlink:type="simple">hoto68@mail.ru</email><xref ref-type="aff" rid="aff-2"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Данилов</surname><given-names>Н. А.</given-names></name><name name-style="western" xml:lang="en"><surname>Danilov</surname><given-names>N. A.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Данилов Николай Андреевич – студент</p></bio><email xlink:type="simple">bugager75@gmail.ru</email><xref ref-type="aff" rid="aff-1"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru"><institution>МИ СВФУ им. М.К. Аммосова</institution><country>Россия</country></aff><aff xml:lang="en"><institution>Medical University of the MK Ammosov North-Eastern Federal University</institution><country>Russian Federation</country></aff></aff-alternatives><aff-alternatives id="aff-2"><aff xml:lang="ru"><institution>ЯНЦ КМП</institution><country>Россия</country></aff><aff xml:lang="en"><institution>YSC CMP</institution><country>Russian Federation</country></aff></aff-alternatives><pub-date pub-type="collection"><year>2017</year></pub-date><pub-date pub-type="epub"><day>26</day><month>08</month><year>2025</year></pub-date><volume>0</volume><issue>1</issue><fpage>15</fpage><lpage>16</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Иванова О.Н., Гольдерова А.С., Данилов Н.А., 2025</copyright-statement><copyright-year>2025</copyright-year><copyright-holder xml:lang="ru">Иванова О.Н., Гольдерова А.С., Данилов Н.А.</copyright-holder><copyright-holder xml:lang="en">Ivanova O.N., Golderova A.N., Danilov N.A.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://ymj.elpub.ru/jour/article/view/889">https://ymj.elpub.ru/jour/article/view/889</self-uri><abstract><p>Статья посвящена актуальной проблеме современной медицины – изучению цитомегаловирусной инфекции. Была обследована группа детей в возрасте от 2 до 5 лет, часто болеющих ОРВИ с субфебрилитетом неясного генеза с положительными ИФА и ПЦР на цитомегаловирус (ЦМВ). Выявлено, что у детей с ЦМВ отмечены снижение содержания естественных киллеров (CD16+), Т-хелперов (CD4+), цитотоксических Т-лимфоцитов (CD8+), повышение – IgМ, IgG и ЦИК.</p></abstract><trans-abstract xml:lang="en"><p>The article is devoted to an actual problem of modern medicine - the study of cytomegalovirus infection. A group of children aged 2 to 5 years, often suffering from SARS with low-grade fever of unknown genesis with positive ELISA and PCR for cytomegalovirus (CMV) was examined. It was found that in children with CMV reduction of natural killer cells (CD16 +), T-helper cells (CD4 +), cytotoxic T lymphocytes (CD8 +), increase of IgM, IgG, and the CEC were marked.</p></trans-abstract><kwd-group xml:lang="ru"><kwd>иммунитет</kwd><kwd>вирус</kwd><kwd>антитело</kwd><kwd>иммуноглобулин</kwd><kwd>герпес</kwd><kwd>заболевание</kwd><kwd>цитомегаловирус</kwd></kwd-group><kwd-group xml:lang="en"><kwd>immunity</kwd><kwd>virus</kwd><kwd>antibody</kwd><kwd>immunoglobulin</kwd><kwd>herpes</kwd><kwd>disease</kwd><kwd>cytomegalovirus</kwd></kwd-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Дидковский Н.А. Индукторы интерферона — новый перспективный класс имммуномодуляторов / Н.А. Дидковский, И.К. Малашенкова, Э.Б. Тазулахова // Аллергология. - 1998. - № 4. – С. 26-32.</mixed-citation><mixed-citation xml:lang="en">Didkovskiy N.A. 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