<?xml version="1.0" encoding="UTF-8"?>
<!DOCTYPE article PUBLIC "-//NLM//DTD JATS (Z39.96) Journal Publishing DTD v1.3 20210610//EN" "JATS-journalpublishing1-3.dtd">
<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">ymj</journal-id><journal-title-group><journal-title xml:lang="ru">Якутский медицинский журнал</journal-title><trans-title-group xml:lang="en"><trans-title>Yakut Medical Journal</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">1813-1905</issn><issn pub-type="epub">2312-1017</issn><publisher><publisher-name>ЯНЦ КМП</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="doi">10.1234/YMJ.2022.77.07</article-id><article-id custom-type="elpub" pub-id-type="custom">ymj-85</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>ОРИГИНАЛЬНЫЕ ИССЛЕДОВАНИЯ</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>ORIGINAL RESEARCH</subject></subj-group></article-categories><title-group><article-title>Уровень стероидных гормонов в организме борцов в разные периоды тренировочного цикла в условиях Севера</article-title><trans-title-group xml:lang="en"><trans-title>The level of steroid hormones in the body of wrestlers at different periods of the training cycle in the conditions of the North</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Охлопкова</surname><given-names>Е. Д.</given-names></name><name name-style="western" xml:lang="en"><surname>Okhlopkova</surname><given-names>E. D.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Охлопкова Елена Дмитриевна – к.б.н., с.н.с.</p></bio><bio xml:lang="en"><p>Elena D. Okhlopkova − Candidate of Biological Sciences, senior researcher, laboratory of biochemistry and immunology, Yakutsk Scientific Center for Complex Medical Problems.</p></bio><email xlink:type="simple">elena_ohlopkova@mail.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Ефремова</surname><given-names>С. Д.</given-names></name><name name-style="western" xml:lang="en"><surname>Efremova</surname><given-names>S. D.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Ефремова Светлана Дмитриевна – м.н.с.</p></bio><bio xml:lang="en"><p>Svetlana D. Efremova − junior researcher laboratory of biochemistry and immunology, Yakutsk Scientific Center for Complex Medical Problems.</p></bio><email xlink:type="simple">esd64@mail.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Румянцев</surname><given-names>Е. К.</given-names></name><name name-style="western" xml:lang="en"><surname>Rumyantsev</surname><given-names>E. K.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Румянцев Егор Константинович – м.н.с.</p></bio><bio xml:lang="en"><p>Egor K. Rumyantsev – junior researcher of the Arctic Medical Center, Yakutsk Scientific Center for Complex Medical Problems.</p></bio><email xlink:type="simple">tzeentch1993@mail.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Григорьева</surname><given-names>А. A.</given-names></name><name name-style="western" xml:lang="en"><surname>Grigorieva</surname><given-names>A. A.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Григорьева Анастасия Анатольевна – м.н.с.</p></bio><bio xml:lang="en"><p>Anastasia A. Grigorieva − researcher, of the arctic medical center, Yakutsk Scientific Center for Complex Medical Problems.</p></bio><email xlink:type="simple">Nastiagrigoryeva@gmail.com</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Олесова</surname><given-names>Л. Д.</given-names></name><name name-style="western" xml:lang="en"><surname>Olesova</surname><given-names>L. D.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Олесова Любовь Дыгыновна – к.б.н., в.н.с. - руковод. лаб.</p></bio><bio xml:lang="en"><p>Lyubov D. Olesova - Candidate of Biological Sciences, Leading Researcher - Head of the Laboratory of Biochemistry, Yakutsk Scientific Center for Complex Medical Problems.</p></bio><email xlink:type="simple">oles59@mail.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Миронова</surname><given-names>Г. Е.</given-names></name><name name-style="western" xml:lang="en"><surname>Mironova</surname><given-names>G. E.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Миронова Галина Егоровна – д.б.н., проф. ИЕН ФГАОУ ВО СВФУ им. М.К. Аммосова.</p></bio><bio xml:lang="en"><p>Galina E. Mironova − Professor of the Department of Biology of the Institute of Natural Sciences of the M.K. Ammosov North-Eastern Federal university, Doctor of Biological Sciences, Professor.</p></bio><email xlink:type="simple">mirogalin@mail.ru</email><xref ref-type="aff" rid="aff-2"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru"><institution>ФГБНУ «ЯНЦ КМП»</institution><country>Россия</country></aff><aff xml:lang="en"><institution>Yakutsk Scientific Center for Complex Medical Problems</institution><country>Russian Federation</country></aff></aff-alternatives><aff-alternatives id="aff-2"><aff xml:lang="ru"><institution>ФГАОУ ВО СВФУ им. М.К. Аммосова</institution><country>Россия</country></aff><aff xml:lang="en"><institution>M.K. Ammosov North-Eastern Federal university</institution><country>Russian Federation</country></aff></aff-alternatives><pub-date pub-type="collection"><year>2022</year></pub-date><pub-date pub-type="epub"><day>03</day><month>02</month><year>2025</year></pub-date><volume>0</volume><issue>1</issue><fpage>27</fpage><lpage>31</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Охлопкова Е.Д., Ефремова С.Д., Румянцев Е.К., Григорьева А.A., Олесова Л.Д., Миронова Г.Е., 2025</copyright-statement><copyright-year>2025</copyright-year><copyright-holder xml:lang="ru">Охлопкова Е.Д., Ефремова С.Д., Румянцев Е.К., Григорьева А.A., Олесова Л.Д., Миронова Г.Е.</copyright-holder><copyright-holder xml:lang="en">Okhlopkova E.D., Efremova S.D., Rumyantsev E.K., Grigorieva A.A., Olesova L.D., Mironova G.E.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://ymj.elpub.ru/jour/article/view/85">https://ymj.elpub.ru/jour/article/view/85</self-uri><abstract><p>Проведена оценка уровня стероидных гормонов у якутских борцов вольного стиля в предсоревновательный и восстановительный периоды в весенний сезон. Исследованы уровни тестостерона, дегидроэпиандростерона, дегидроэпиандростерон-сульфата и кортизола в сыворотке крови высококвалифицированных спортсменов и студентов вуза, занимающихся физкультурой не реже 2 раз в неделю.</p></abstract><trans-abstract xml:lang="en"><p>The aim: to assess the level of steroid hormones in the Yakut freestyle wrestlers in the pre-competitive and recovery period in the spring season. The levels of testosterone, dehydroepiandrosterone, dehydroepiandrosterone sulfate and cortisol in the blood serum of highly qualified athletes and university students who go in for physical education at least 2 times a week were studied. The lower testosterone content in wrestlers revealed before the competition indicates the intensity of training loads and psycho-emotional stress. A slight increase in testosterone levels after 7-10 days and its excess of the basal level after 30 days after the competition indicates the adequacy of recovery. The level of cortisol is characterized by a significantly lower content before the competition, and a continuing decrease after the competition in the second period (p=0.027; p=0.003) than in the control group. A similar character of changes in the level is also observed in relation to DHEAS. Levels of all steroid hormones 30 days after the competition, exceeding their pre-competition levels, indicates adaptation to stress and shows the recovery of the body. The growth of the T/K index in athletes 7-10 years after the competition indicates the beginning of recovery processes in the body. A higher level of testosterone, cortisol and DHEAS (p = 0.003) - the hormone of the precursor of these hormones one month after the competition indicates a moderate activation of the pituitary-adrenal system to balance the processes of anabolism and catabolism.</p></trans-abstract><kwd-group xml:lang="ru"><kwd>стероидные гормоны</kwd><kwd>кортизол</kwd><kwd>тестостерон</kwd><kwd>ДГЭА</kwd><kwd>борцы</kwd><kwd>период тренировочного цикла</kwd></kwd-group><kwd-group xml:lang="en"><kwd>steroid hormones</kwd><kwd>cortisol</kwd><kwd>testosterone</kwd><kwd>DHEA</kwd><kwd>wrestlers</kwd><kwd>training cycle period</kwd></kwd-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Виру A.A. Гормоны и спортивная работоспособность / A.A. Виру, П.К. Кырге. - М., 1983. - 159 с.</mixed-citation><mixed-citation xml:lang="en">Viru A.A. Hormones and sports performance /A.A. Viru, P.K. Kyrge М. - 1983. - 159 р.</mixed-citation></citation-alternatives></ref><ref id="cit2"><label>2</label><citation-alternatives><mixed-citation xml:lang="ru">Грязных А.В. Гормональные и метаболические сдвиги при физической нагрузке и приеме пищи / А.В. Грязных.– Курган: Изд-во Курганского гос. ун-та, 2011. – 92 с.</mixed-citation><mixed-citation xml:lang="en">Gryaznykh A.V. Hormonal and metabolic changes during exercise and food intake/ A.V. Gryaznykh - Kurgan: Publishing House of the Kurgan State University, 2011. - 92 p.</mixed-citation></citation-alternatives></ref><ref id="cit3"><label>3</label><citation-alternatives><mixed-citation xml:lang="ru">Кубасов Р.В. Гормональные изменения в ответ на экстремальные факторы внешней среды / Р.В. Кубасов // Вестник РАМН. - 2014; 9–10: С.102–109.</mixed-citation><mixed-citation xml:lang="en">Kubasov R.V. Hormonal changes in response to extreme environmental factors / R.V. Kubasov // Bulletin of the Russian Academy of Medical Sciences. 2014; 9–10:102–109</mixed-citation></citation-alternatives></ref><ref id="cit4"><label>4</label><citation-alternatives><mixed-citation xml:lang="ru">Меерсон Ф.З. Адаптация к стрессорным ситуациям и физическим нагрузкам / Ф.З. Меерсон, М.Г. Пшеничников. - М., 1988. - 256 с.</mixed-citation><mixed-citation xml:lang="en">Meyerson F.Z. Adaptation to stressful situations and physical loads / F.Z. Meyerson, M.G. Pshenichnikov. M. - 1988. - 256 p.</mixed-citation></citation-alternatives></ref><ref id="cit5"><label>5</label><citation-alternatives><mixed-citation xml:lang="ru">Обут Т.А. Лимитирующий стрессреактивность эффект дегидроэпиандростерон-сульфата и его механизмы / Т.А. Обут, М.А. Овсюкова, О.П. Черкасова // Бюл. Экспер. биолог и мед. - 2003. –№ 3. –С. 269—271.</mixed-citation><mixed-citation xml:lang="en">Obut T.A. Stress-reactivity-limiting effect of dehydroepiandrosterone sulfate and its mechanisms / Т.А. Obut, M.A. Ovsyukova, O.P. Cherkasov // Bul. Expert. biol. and med. 2003. – No 3. -Р. 269-271.</mixed-citation></citation-alternatives></ref><ref id="cit6"><label>6</label><citation-alternatives><mixed-citation xml:lang="ru">Оценка адекватности восстановительного периода в профессиональной деятельности при физических и психоэмоциональных нагрузках по гормональному статусу организма / Р.С. Рахманов, Т.В. Блинова, Разгулин С.А. [и др.]// Медицинский альманах. – 2017. – №2(47). – С.146-150.</mixed-citation><mixed-citation xml:lang="en">Assessment of the adequacy of the recovery period in professional activity during physical and psycho-emotional stresses according to the hormonal status of the body / R.S. Rakhmanov, T.V. Blinova, Razgulin S.A. etc.// Medical almanac. - 2017. - No. 2 (47). - P.146-150.</mixed-citation></citation-alternatives></ref><ref id="cit7"><label>7</label><citation-alternatives><mixed-citation xml:lang="ru">Роживанов P.В. Дегидроэпиандростерон: физиологическая роль и возможности применения в качестве медикаментозного средства / P.В.Роживанов, В.В. Вакс// Проблемы эндокринологии. – 2005. – Т.51, №2. – С.46-51. https://doi.org/10.14341/probl200551246-51</mixed-citation><mixed-citation xml:lang="en">Rozhivanov P.V. Dehydroepiandrosterone: physiological role and possibilities of use as a drug / Rozhivanov P.V., Vaks V.V. // Problems of Endocrinology. – 2005;51(2):46-51. https://doi.org/10.14341/probl200551246-51</mixed-citation></citation-alternatives></ref><ref id="cit8"><label>8</label><citation-alternatives><mixed-citation xml:lang="ru">Синдром перетренированности как функциональное расстройство сердечно-сосудистой системы, обусловленное физическими нагрузками / В.А. Бадтиева, В.И. Павлов, А.С. Шарыкин [и др.] // Российский кардиологический журнал. – 2018. – Т. 23, №6.- С.180-190. http://dx.doi.org/10.15829/1560-4071-2018-6-180-190.</mixed-citation><mixed-citation xml:lang="en">Overtraining syndrome as a functional disorder of the cardiovascular system caused by physical activity. B.A. Badtieva, V.I. Pavlov, A.S. Sharykin, et al. // Russian Journal of Cardiology. – 2018. – №23(6).-Р.180-190. http://dx.doi.org/10.15829/1560-4071-2018-6-180-190.</mixed-citation></citation-alternatives></ref><ref id="cit9"><label>9</label><citation-alternatives><mixed-citation xml:lang="ru">Стаценко Е.А. Влияние тренировочных нагрузок и фармакологической поддержки на показатели иммунной и гормональной систем у высококвалифицированных спортсменов циклических видов спорта / Е.А. Станценко // Медицинский журнал. - 2008. - №1. - С. 64-66.</mixed-citation><mixed-citation xml:lang="en">Statsenko E.A. Influence of training loads and pharmacological support on the parameters of the immune and hormonal systems in highly qualified athletes of cyclic sports / E.A. Stantsenko // Medical Journal. - 2008. - №. 1. - Р. 64-66.</mixed-citation></citation-alternatives></ref><ref id="cit10"><label>10</label><citation-alternatives><mixed-citation xml:lang="ru">Тюзиков И.А. Дегидроэпиандростерон у мужчин: потенциальные физиологические эффекты с позиции доказательной медицины / И.А.Тюзиков // Эффективная фармакотерапия. - 2020. - Т. 16, № 20. - С. 44–51. DOI 10.33978/2307-3586-2020-16-20-44-51.</mixed-citation><mixed-citation xml:lang="en">Tyuzikov I.A. Dehydroepiandrosterone in men: potential physiological effects from the standpoint of evidence-based medicine / I.A.Tyuzikov // Effective pharmacotherapy. 2020. V. 16. No 20. Р. 44–51. DOI 10.33978/2307-3586-2020-16-20-44-51</mixed-citation></citation-alternatives></ref><ref id="cit11"><label>11</label><citation-alternatives><mixed-citation xml:lang="ru">Уровень тестостерона и индекс массы тела у молодых людей в Якутии /А.А. Никанорова, Н.А. Барашков, С.С. Находкин [и др.] //Якутский медицинский журнал. - 2021.- №4. - С.60-64. DOI 10.25789/YMJ.2021.76.14</mixed-citation><mixed-citation xml:lang="en">Testosterone level and body mass index in young people in Yakutia /A.A. Nikanorova, N.A. Barashkov, S.S. Nakhodkin [et al.] // Yakut medical journal. 2021;4: P. 60-64, DOI 10.25789/YMJ.2021.76.14</mixed-citation></citation-alternatives></ref><ref id="cit12"><label>12</label><citation-alternatives><mixed-citation xml:lang="ru">Аlia, P. Profile, Mean residence time of ACTH and Cortisol responses after low and standard ACTH tests in healthy volunteers / P. Alia, C. Villabona, O. Gimenez // Clin, endocrinol. 2006. - V.65. - No 3. - P. 346-351.</mixed-citation><mixed-citation xml:lang="en">Аlia, P. Profile, Mean residence time of ACTH and Cortisol responses after low and standard ACTH tests in healthy volunteers / P. Alia, C. Villabona, O. Gimenez // Clin, endocrinol. 2006. - V.65. - No 3. - P. 346-351.</mixed-citation></citation-alternatives></ref><ref id="cit13"><label>13</label><citation-alternatives><mixed-citation xml:lang="ru">Anderson T. Cortisol and testosterone dynamics following exhaustive endurance exercise /T.Anderson, A.R. Lane, A.C. Hackney // Eur J Appl Physiol 2016; 116(8): 1503–1509 https://doi.org/10.1007/s00421-016-3406-y</mixed-citation><mixed-citation xml:lang="en">Anderson T. Cortisol and testosterone dynamics following exhaustive endurance exercise /T.Anderson, A.R. Lane, A.C. Hackney // Eur J Appl Physiol 2016; 116(8): 1503–1509 https://doi.org/10.1007/s00421-016-3406-y</mixed-citation></citation-alternatives></ref><ref id="cit14"><label>14</label><citation-alternatives><mixed-citation xml:lang="ru">Anticipatory cortisol, testosterone and psychological responses to judo competition in young men /A. Salvador, F. Suay, E. Gonzalez-Bono [et.ol] // Psychoneuro endocrinology. 2003.-28:364-375.</mixed-citation><mixed-citation xml:lang="en">Anticipatory cortisol, testosterone and psychological responses to judo competition in young men /A. Salvador, F. Suay, E. Gonzalez-Bono [et.ol] // Psychoneuro endocrinology. 2003.-28:364-375.</mixed-citation></citation-alternatives></ref><ref id="cit15"><label>15</label><citation-alternatives><mixed-citation xml:lang="ru">Banfi, G. Usefulness of free testosterone. Cortisol ratio during a season of elite speed skating athletes / G. Banfi, A.J. Dolci // Sports med phys. fitness. -2006. V.46. – No 4. p. 611-616.</mixed-citation><mixed-citation xml:lang="en">Banfi, G. Usefulness of free testosterone. Cortisol ratio during a season of elite speed skating athletes / G. Banfi, A.J. Dolci // Sports med phys. fitness. -2006. V.46. – No 4. p. 611-616.</mixed-citation></citation-alternatives></ref><ref id="cit16"><label>16</label><citation-alternatives><mixed-citation xml:lang="ru">Elias, M. Serum cortisol, testosterone and testosterone-binding globulin responses to competitive fighting in human males. Aggressive Behavior. 1981; 7: 215-224.</mixed-citation><mixed-citation xml:lang="en">Elias, M. Serum cortisol, testosterone and testosterone-binding globulin responses to competitive fighting in human males. Aggressive Behavior. 1981; 7: 215-224.</mixed-citation></citation-alternatives></ref><ref id="cit17"><label>17</label><citation-alternatives><mixed-citation xml:lang="ru">Kremer W.J. Endocrine system, sport and physical activity / W.J. Kremer, A.D. Rogol; per. from English. - Kiev: Olympic Literature. 2008. - 600 p.</mixed-citation><mixed-citation xml:lang="en">Kremer W.J. Endocrine system, sport and physical activity / W.J. Kremer, A.D. Rogol; per. from English. - Kiev: Olympic Literature. 2008. - 600 p.</mixed-citation></citation-alternatives></ref><ref id="cit18"><label>18</label><citation-alternatives><mixed-citation xml:lang="ru">Neurobiological and neuropsychiatric effects of dehydroepiandrosterone (DHEA) and DHEA sulfate (DHEAS)/ N.Maninger, O.M. Wolkowitz, V.I. Reus et al. // Frontiers in Neuroendocrinology 2009; 30: 65—91.</mixed-citation><mixed-citation xml:lang="en">Neurobiological and neuropsychiatric effects of dehydroepiandrosterone (DHEA) and DHEA sulfate (DHEAS)/ N.Maninger, O.M. Wolkowitz, V.I. Reus et al. // Frontiers in Neuroendocrinology 2009; 30: 65—91.</mixed-citation></citation-alternatives></ref><ref id="cit19"><label>19</label><citation-alternatives><mixed-citation xml:lang="ru">Preliminary results on mood state, salivary testosterone: cortisol ratio and team performance in a professional soccer team / E. Filaire, X. Bernain, M. Sagnol et al, European Journa of Applied Physiology. 2001a- 86: 179-184.</mixed-citation><mixed-citation xml:lang="en">Preliminary results on mood state, salivary testosterone: cortisol ratio and team performance in a professional soccer team / E. Filaire, X. Bernain, M. Sagnol et al, European Journa of Applied Physiology. 2001a- 86: 179-184.</mixed-citation></citation-alternatives></ref><ref id="cit20"><label>20</label><citation-alternatives><mixed-citation xml:lang="ru">Tian, Zh.-jun Effect of aerobic exercise on testosterone, Cortisol, HDL and low density of angiotensin II on myocardial contractility in rats / Zh.-jun Tian // J. Xi'an Inst. Phys. educ. 2001. - V. 18. - No 1. - P. 28-31.</mixed-citation><mixed-citation xml:lang="en">Tian, Zh.-jun Effect of aerobic exercise on testosterone, Cortisol, HDL and low density of angiotensin II on myocardial contractility in rats / Zh.-jun Tian // J. Xi'an Inst. Phys. educ. 2001. - V. 18. - No 1. - P. 28-31.</mixed-citation></citation-alternatives></ref><ref id="cit21"><label>21</label><citation-alternatives><mixed-citation xml:lang="ru">Zhang, Y. / Y. Zhang // Wuhan Inst. Physiol, educ. 2005. - V. 39. - № 3. - P. 58-62.</mixed-citation><mixed-citation xml:lang="en">Zhang, Y. / Y. Zhang // Wuhan Inst. Physiol, educ. 2005. - V. 39. - № 3. - P. 58-62.</mixed-citation></citation-alternatives></ref></ref-list><fn-group><fn fn-type="conflict"><p>The authors declare that there are no conflicts of interest present.</p></fn></fn-group></back></article>
