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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">ymj</journal-id><journal-title-group><journal-title xml:lang="ru">Якутский медицинский журнал</journal-title><trans-title-group xml:lang="en"><trans-title>Yakut Medical Journal</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">1813-1905</issn><issn pub-type="epub">2312-1017</issn><publisher><publisher-name>ЯНЦ КМП</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="doi">10.25789/YMJ.2019.65.08</article-id><article-id custom-type="elpub" pub-id-type="custom">ymj-835</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>МЕТОДЫ ДИАГНОСТИКИ И ЛЕЧЕНИЯ</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>METHODS OF DIAGNOSIS AND TREATMENT</subject></subj-group></article-categories><title-group><article-title>Первая трансплантация сердца человека в дальневосточном федеральном округе российской Федерации</article-title><trans-title-group xml:lang="en"><trans-title>The first human heart transplant in the Far Eastern Federal District of the Russian Federation</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Захаров</surname><given-names>П. И.</given-names></name><name name-style="western" xml:lang="en"><surname>Zakharov</surname><given-names>P. I.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Захаров Петр Иванович – д.м.н., врач сердеч.-сосуд. хирург, зав. кардиохирургич. отд.</p></bio><bio xml:lang="en"><p>Zakharov Petr Ivanovich - MD, Cardiovascular Surgeon, Head of the Cardiac Surgery Department of the Clinical Center</p><p>677019, Yakutsk, Sergelyakhskoye hwy, 4</p><p>+79142708124</p></bio><email xlink:type="simple">pizaharov@mail.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Охлопков</surname><given-names>М. Е.</given-names></name><name name-style="western" xml:lang="en"><surname>Okhlopkov</surname><given-names>M. E.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Охлопков Михаил Егорович – к.м.н., министр здравоохранения Республики Карелия</p></bio><bio xml:lang="en"><p>Okhlopkov Mikhail Egorovich - Candidate of Medical Sciences, Minister of Health of the Republic of Karelia</p><p>Petrozavodsk, Lenin Avenue, 6</p><p>+78142792900</p></bio><xref ref-type="aff" rid="aff-2"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Лугинов</surname><given-names>Н. В.</given-names></name><name name-style="western" xml:lang="en"><surname>Luginov</surname><given-names>N. V.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Лугинов Николай Васильевич – к.м.н., ген. Директор</p></bio><bio xml:lang="en"><p>Luginov Nikolay Vasilievich - Candidate of Medical Sciences, General Director</p><p>677019, Yakutsk, Sergelyakhskoye hwy, 4</p><p>+79142234857</p></bio><email xlink:type="simple">luginovnv@gmail.com</email><xref ref-type="aff" rid="aff-3"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Васильев</surname><given-names>А. И.</given-names></name><name name-style="western" xml:lang="en"><surname>Vasilyev</surname><given-names>A. I.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Васильев Альберт Иванович – к.м.н., директор Клинич. центра</p></bio><bio xml:lang="en"><p>Vasilyev Albert Ivanovich - Candidate of Medical Sciences, Director of the Clinical Center</p><p>677019, Yakutsk, Sergelyakhskoye hwy, 4</p><p>+79245934453</p></bio><xref ref-type="aff" rid="aff-3"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Портнягин</surname><given-names>П. П.</given-names></name><name name-style="western" xml:lang="en"><surname>Portnyagin</surname><given-names>P. P.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Портнягин Петр Петрович – к.м.н., врач сердеч.-сосуд. хирург</p></bio><bio xml:lang="en"><p>Portnyagin Petr Petrovich - Candidate of Medical Sciences, Cardiovascular Surgeon of the Cardiac Surgery Department of the Clinical Center</p><p>677019, Yakutsk, Sergelyakhskoye highway, 4</p><p>+79142910815</p></bio><xref ref-type="aff" rid="aff-4"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Сивцев</surname><given-names>В. С.</given-names></name><name name-style="western" xml:lang="en"><surname>Sivtsev</surname><given-names>V. S.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Сивцев Василий Степанович – к.м.н., врач сердеч.-сосуд. хирург</p></bio><bio xml:lang="en"><p>Sivtsev Vasiliy Stepanovich - Candidate of Medical Sciences, Cardiovascular Surgeon of the Cardiac Surgery Department of the Clinical Center</p><p>677019, Yakutsk, Sergelyakhskoye hwy, 4</p><p>+79141080683</p></bio><xref ref-type="aff" rid="aff-4"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Ломоносов</surname><given-names>С. В.</given-names></name><name name-style="western" xml:lang="en"><surname>Lomonosov</surname><given-names>S. V.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Ломоносов Сергей Владимирович – врач сердеч.-сосуд. хирург</p></bio><bio xml:lang="en"><p>Lomonosov Sergey Vladimirovich - Cardiovascular Surgeon of the Cardiac Surgery Department of the Clinical Center</p><p>677019, Yakutsk, Sergelyakhskoye hwy, 4</p><p>+79243663121</p></bio><xref ref-type="aff" rid="aff-3"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Павлов</surname><given-names>В. И.</given-names></name><name name-style="western" xml:lang="en"><surname>Pavlov</surname><given-names>V. I.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Павлов Василий Иванович – врач сердеч.-сосуд. хирург</p></bio><bio xml:lang="en"><p>Pavlov Vasiliy Ivanovich - Cardiovascular Surgeon of the Cardiac Surgery Department of the Clinical Center</p><p>677019, Yakutsk, Sergelyakhskoye hwy, 4</p><p>+79243609248</p></bio><xref ref-type="aff" rid="aff-3"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Васильев</surname><given-names>А. Г.</given-names></name><name name-style="western" xml:lang="en"><surname>Vasilyev</surname><given-names>A. G.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Васильев Анатолий Гаврильевич – врач сердеч.-сосуд. хирург</p></bio><bio xml:lang="en"><p>Vasilyev Anatoly Gavrilyevich - Cardiovascular Surgeon of the Cardiac Surgery Department of the Clinical Center</p><p>677019, Yakutsk, Sergelyakhskoye hwy, 4</p><p>79791139733</p></bio><xref ref-type="aff" rid="aff-4"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Максимова</surname><given-names>А. А.</given-names></name><name name-style="western" xml:lang="en"><surname>Maksimova</surname><given-names>A. A.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Максимова Алена Алексеевна – врач сердеч.-сосуд. хирург</p></bio><bio xml:lang="en"><p>Maksimova Alena Alekseevna - Cardiovascular Surgeon of the Cardiac Surgery Department of the Clinical Center</p><p>677019, Yakutsk, Sergelyakhskoye hwy, 4</p><p>+79142921904</p></bio><xref ref-type="aff" rid="aff-4"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Томская</surname><given-names>Т. Ю.</given-names></name><name name-style="western" xml:lang="en"><surname>Tomskaya</surname><given-names>T. Yu.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Томская Татьяна Юрьевна – к.м.н., зав. кардиологич. отд.</p></bio><bio xml:lang="en"><p>Tomskaya Tatyana Yuryevna - Candidate of Medical Sciences, Head of the Cardiology Department of the Clinical Center</p><p>677019, Yakutsk, Sergelykhskoye hwy, 4</p><p>79792269549</p></bio><xref ref-type="aff" rid="aff-3"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Федорова</surname><given-names>А. А.</given-names></name><name name-style="western" xml:lang="en"><surname>Fedorova</surname><given-names>A. A.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Федорова Алла Анатольевна – врач кардиолог</p></bio><bio xml:lang="en"><p>Fedorova Alla Anatolyevna - Cardiologist, Cardiology Department, Clinical Center</p><p>677019, Yakutsk, Sergelyakhskoye hwy, 4</p><p>+79644193717</p></bio><xref ref-type="aff" rid="aff-3"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Булатов</surname><given-names>А. В.</given-names></name><name name-style="western" xml:lang="en"><surname>Bulatov</surname><given-names>A. V.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Булатов Алквиад Валентинович – к.м.н., зав. ОАРИТ</p></bio><bio xml:lang="en"><p>Bulatov Alkviad Valentinovich - Candidate of Medical Sciences, Head of the Department of Anaesthesiology, Resuscitation and Intensive Therapy (Cardiology) of the Clinical Center</p><p>677019, Yakutsk, Sergelyakhskoye hwy, 4</p><p>+79142719426</p></bio><xref ref-type="aff" rid="aff-4"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Коростелев</surname><given-names>А. С.</given-names></name><name name-style="western" xml:lang="en"><surname>Korostelev</surname><given-names>A. S.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Коростелев Александр Сергеевич – врач анестезиолог-реаниматолог</p></bio><bio xml:lang="en"><p>Korostelev Alexander Sergeyevich - Anaesthesiologist-resuscitator of the Department of Anaesthesiology, Resuscitation and Intensive Therapy (Cardiology) of the Clinical Center</p><p>677019, Yakutsk, Sergelyakhskoye hwy, 4</p><p>+79247639300</p></bio><xref ref-type="aff" rid="aff-4"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Бугаев</surname><given-names>Г. Д.</given-names></name><name name-style="western" xml:lang="en"><surname>Bugaev</surname><given-names>G. D.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Бугаев Григорий Дмитриевич – зам. директора Клинико-диагностич. Центра</p></bio><bio xml:lang="en"><p>Bugaev Grigoriy Dmitriyevich - Deputy Director of the Clinical and Diagnostic Center</p><p>677019, Yakutsk, Sergelyakhskoye hwy, 4, +79141101587</p></bio><xref ref-type="aff" rid="aff-3"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Тотонов</surname><given-names>А. М.</given-names></name><name name-style="western" xml:lang="en"><surname>Totonov</surname><given-names>A. M.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Тотонов Афанасий Михайлович – врач паталогоанатом</p></bio><bio xml:lang="en"><p>Totonov Afanasiy Mikhailovich - Pathologist of the Pathological-Anatomical Department of the Clinical Diagnostic Center</p><p>677019, Yakutsk, Sergelyakhskoye hwy, 4</p></bio><xref ref-type="aff" rid="aff-3"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru"><institution>ГАУ РС(Я) «Республиканская больница №1-Национальный центр медицины»</institution><country>Россия</country></aff><aff xml:lang="en"><institution>State Autonomous Institution of the Republic of Sakha (Yakutia) «Republican Hospital №1-National Center of Medicine»</institution><country>Russian Federation</country></aff></aff-alternatives><aff xml:lang="en" id="aff-2"><institution>Ministry of Health of Karelia</institution><country>Russian Federation</country></aff><aff-alternatives id="aff-3"><aff xml:lang="ru"><institution>ГАУ РС(Я) «Республиканская больница №1-Национальный центр медицины»</institution><country>Россия</country></aff><aff xml:lang="en"><institution>State Autonomous Institution of the Republic of Sakha (Yakutia) “Republican Hospital No. 1-National Center of Medicine”</institution><country>Russian Federation</country></aff></aff-alternatives><aff-alternatives id="aff-4"><aff xml:lang="ru"><institution>ГАУ РС(Я) «Республиканская больница №1-Национальный центр медицины»</institution><country>Россия</country></aff><aff xml:lang="en"><institution>State Autonomous Institution of the Republic of Sakha (Yakutia) “Republican Hospital №1-National Center of Medicine”</institution><country>Russian Federation</country></aff></aff-alternatives><pub-date pub-type="collection"><year>2019</year></pub-date><pub-date pub-type="epub"><day>16</day><month>08</month><year>2025</year></pub-date><volume>0</volume><issue>1</issue><fpage>28</fpage><lpage>31</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Захаров П.И., Охлопков М.Е., Лугинов Н.В., Васильев А.И., Портнягин П.П., Сивцев В.С., Ломоносов С.В., Павлов В.И., Васильев А.Г., Максимова А.А., Томская Т.Ю., Федорова А.А., Булатов А.В., Коростелев А.С., Бугаев Г.Д., Тотонов А.М., 2025</copyright-statement><copyright-year>2025</copyright-year><copyright-holder xml:lang="ru">Захаров П.И., Охлопков М.Е., Лугинов Н.В., Васильев А.И., Портнягин П.П., Сивцев В.С., Ломоносов С.В., Павлов В.И., Васильев А.Г., Максимова А.А., Томская Т.Ю., Федорова А.А., Булатов А.В., Коростелев А.С., Бугаев Г.Д., Тотонов А.М.</copyright-holder><copyright-holder xml:lang="en">Zakharov P.I., Okhlopkov M.E., Luginov N.V., Vasilyev A.I., Portnyagin P.P., Sivtsev V.S., Lomonosov S.V., Pavlov V.I., Vasilyev A.G., Maksimova A.A., Tomskaya T.Y., Fedorova A.A., Bulatov A.V., Korostelev A.S., Bugaev G.D., Totonov A.M.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://ymj.elpub.ru/jour/article/view/835">https://ymj.elpub.ru/jour/article/view/835</self-uri><abstract><p>В статье представлен первый опыт трансплантации сердца человека в Дальневосточном федеральном округе. Описаны клинический случай, хирургическая техника этапов ортотопической пересадки сердца. Краткий обзор состояния трансплантации сердца на сегодняшний день и обсуждение.</p></abstract><trans-abstract xml:lang="en"><p>The article presents the first experience of human heart transplantation in the Far Eastern Federal District. The clinical case and the surgical technique of the stages of orthotopic heart transplantation are described. A brief overview of the current state of heart transplantation and discussion are presented.</p></trans-abstract><kwd-group xml:lang="ru"><kwd>трансплантация сердца</kwd><kwd>первый опыт</kwd><kwd>иммуносупрессия</kwd><kwd>отторжение</kwd><kwd>донор</kwd><kwd>Якутия</kwd><kwd>дальневосточный федеральный округ</kwd></kwd-group><kwd-group xml:lang="en"><kwd>heart transplantation</kwd><kwd>first experience</kwd><kwd>Yakutia</kwd><kwd>Far Eastern Federal District</kwd></kwd-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Готье С.В. Инновации в трансплантологии: развитие программы трансплантации сердца в российской Федерации / С.В. Готье // Патология кровообращения и кардиохирургия. 2017; 21(35): 61-68. http://dx.doi.org/10.21688/1681-3472-2017-3S-61-68.</mixed-citation><mixed-citation xml:lang="en">Gautier S.V. 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