ymjЯкутский медицинский журналYakut Medical Journal1813-19052312-1017ЯНЦ КМП10.25789/YMJ.2020.72.12ymj-723Research ArticleМЕТОДЫ ДИАГНОСТИКИ И ЛЕЧЕНИЯMETHODS OF DIAGNOSIS AND TREATMENTКлинико-аудиологический и генеалогический анализ случаев нарушения слуха в Республике БурятияClinical, audiological and genealogical analysis of hearing disorders in the Republic of Buryatiahttps://orcid.org/0000-0001-6866-9462ПшенниковаВ. Г.PshennikovaV. G.

Пшенникова Вера Геннадиевна - к.б.н., в.н.с.-руковод. лаб.

Pshennikova Vera Gennadievna - Ph.D., Head of laboratory

Yakutsk, 677010

psennikovavera@mail.ruhttps://orcid.org/0000-0002-8659-0886ТерютинФ. М.TeryutinF. M.

Терютин Федор Михайлович - к.м.н., н.с.

Teryutin Fedor Mikhailovich - Ph.D., Researcher

Yakutsk, 677010

rest26@mail.ruhttps://orcid.org/0000-0002-6984-7934БарашковН. А.BarashkovN. A.

Барашков Николай Алексеевич - к.б.н., в.н.с.-руковод. лаб.

Barashkov Nikolay Alekseevich - Ph.D., Head of laboratory

Yakutsk

barashkov2004@mail.ruhttps://orcid.org/0000-0002-2143-0021КононоваС. К.KononovaS. K.

Кононова Сардана Кононовна - к.б.н., с.н.с.

Kononova Sardana Kononovna - Ph.D., Researcher

Yakutsk

konsard@rambler.ruhttps://orcid.org/0000-0003-0914-3609СоловьевА. В.SolovyevA. V.

Соловьев Айсен Васильевич - к.б.н., н.с.

Solovyev Aisen Vasilievich - Ph.D., Researcher

Yakutsk, 677010

nelloann@mail.ruhttps://orcid.org/0000-0002-2936-5818РомановГ. П.RomanovG. P.

Романов Георгий Прокопьевич – н.с.

Romanov Georgii Prokopievich – Researcher

Yakutsk

gpromanov@gmail.comhttps://orcid.org/0000-0002-6952-3868ФедороваС. А.FedorovaS. A.

Федорова Сардана Аркадьевна - д.б.н., зав. науч.-исслед. лаб.

Fedorova Sardana Arkadievna - Ph.D., Head of Laboratory

sardaanafedorova@mail.ruЯкутский научный центр комплексных медицинских проблемРоссияYakut Scientific Center of Сomplex Мedical РroblemsRussian FederationСеверо-Восточный федеральный унт-т им. М.К. АммосоваРоссияAmmosov of the Institute of Natural Sciences, North-Eastern Federal UniversityRussian FederationСеверо-Восточный федеральный унт-т им. М.К. АммосоваРоссияInstitute of Natural Sciences, North-Eastern Federal UniversityRussian Federation202002062025044449Copyright © Пшенникова В.Г., Терютин Ф.М., Барашков Н.А., Кононова С.К., Соловьев А.В., Романов Г.П., Федорова С.А., 20252025Пшенникова В.Г., Терютин Ф.М., Барашков Н.А., Кононова С.К., Соловьев А.В., Романов Г.П., Федорова С.А.Pshennikova V.G., Teryutin F.M., Barashkov N.A., Kononova S.K., Solovyev A.V., Romanov G.P., Fedorova S.A.Данная работа распространяется под лицензией Creative Commons Attribution 4.0.This work is licensed under a Creative Commons Attribution 4.0 License.https://ymj.elpub.ru/jour/article/view/723

В статье впервые представлены результаты клинико-аудиологического и генеалогического анализа случаев нарушений слуха в Республике Бурятия. В результате клинико-аудиологического анализа выборки исследуемых у большинства была установлена двусторонняя глухота по сенсоневральному типу, у остальных - двусторонняя тугоухость различной степени тяжести. Сегрегационный анализ, проведенный в бурятских и русских семьях, позволил предположить наследственный характер случаев нарушения слуха, сегрегирующих по аутосомно-рецессивному типу наследования только в русских семьях.

In this paper we present for the first time the results of the clinical-audiological and genealogical analysis of cases of hearing impairment in the Republic of Buryatia. As a result of the clinical-audiological analysis of the survey sample, the majority of individuals had bilateral deafness of the sensorineural type, the rest had bilateral hearing loss of varying severity. The segregation analysis carried out in Buryat and Russian families made it possible to assume the hereditary nature of cases of hearing impairment, segregating according to an autosomal recessive type of inheritance only in Russian families.

клинико-аудиологический анализклинико-генеалогический анализнаследственная отягощенностьнарушение слухаРеспублика Бурятияclinical-audiological analysisclinical-genealogical analysishereditary burdenhearing impairmentRepublic of BuryatiaРабота выполнена в рамках НИР ЯНЦ КМП «Изучение генетической структуры и груза наследственной патологии популяций Республики Саха (Якутия)», базовой части госзадания Министерства науки и образования РФ (FSRG-2020-0016) и при поддержке грантов РФФИ (18-05- 600035_Арктика, 18-015-00212_A, 20- 015-00328_A).This study was supported by the Project of the Yakut Scientific Center of Complex Medical Problems “Studying the genetic structure and load of hereditary pathology of populations of the Sakha Republic”, the basic part of the state assignment of the Ministry of Science and Education of the Russian Federation (FSRG-2020-0016) and with the support of RFBR grants (18- 05-600035_ Arctic, 18-015-00212_A, 20- 015-00328_A).ReferencesГинтер Е.К. 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The authors declare that there are no conflicts of interest present.