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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">ymj</journal-id><journal-title-group><journal-title xml:lang="ru">Якутский медицинский журнал</journal-title><trans-title-group xml:lang="en"><trans-title>Yakut Medical Journal</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">1813-1905</issn><issn pub-type="epub">2312-1017</issn><publisher><publisher-name>ЯНЦ КМП</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="doi">10.25789/YMJ.2024.87.04</article-id><article-id custom-type="elpub" pub-id-type="custom">ymj-7</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>ОРИГИНАЛЬНЫЕ ИССЛЕДОВАНИЯ</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>ORIGINAL RESEARCH</subject></subj-group></article-categories><title-group><article-title>Сорбционная активность эпителия полости рта у жителей г. Архангельска в зависимости от индекса массы тела</article-title><trans-title-group xml:lang="en"><trans-title>Sorption activity of the epithelium of the oral cavity in residents of Arkhangelsk depending on body mass index</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-1142-4410</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Штаборов</surname><given-names>В. А.</given-names></name><name name-style="western" xml:lang="en"><surname>Shtaborov</surname><given-names>V. A.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Штаборов Вячеслав Анатольевич – к.б.н, с.н.с.</p><p>Архангельск</p></bio><bio xml:lang="en"><p>Shtaborov Vyacheslav A. – Candidate of Biological Sciences, senior researcher, Lab- oratory of Environmental Immunology of the Institute of Natural Adaptations.</p><p>Arkhangelsk</p></bio><email xlink:type="simple">schtaborov@mail.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0001-6219-5964</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Патракеева</surname><given-names>В. П.</given-names></name><name name-style="western" xml:lang="en"><surname>Patrakeeva</surname><given-names>V. P.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Патракеева Вероника Павловна – к.б.н., зав. лаб.</p><p>Архангельск</p></bio><bio xml:lang="en"><p>Patrakeeva Veronika P. – Candidate of Biological Sciences, Head. Laboratory of Ecological Immunology of the Institute of Natural Adaptations.</p><p>Arkhangelsk</p></bio><xref ref-type="aff" rid="aff-1"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru"><institution>Ин-т природных адаптаций ФИЦ комплексного изучения Арктики им. академика Н.П. Лаверова Уральского отд. РАН</institution><country>Россия</country></aff><aff xml:lang="en"><institution>N. Laverov Federal Center for Integrated Arctic Research of the Ural Branch of the Russian Academy of Sciences</institution><country>Russian Federation</country></aff></aff-alternatives><pub-date pub-type="collection"><year>2024</year></pub-date><pub-date pub-type="epub"><day>02</day><month>02</month><year>2025</year></pub-date><volume>0</volume><issue>3</issue><fpage>24</fpage><lpage>28</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Штаборов В.А., Патракеева В.П., 2025</copyright-statement><copyright-year>2025</copyright-year><copyright-holder xml:lang="ru">Штаборов В.А., Патракеева В.П.</copyright-holder><copyright-holder xml:lang="en">Shtaborov V.A., Patrakeeva V.P.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://ymj.elpub.ru/jour/article/view/7">https://ymj.elpub.ru/jour/article/view/7</self-uri><abstract><p>Цель исследования: изучить особенности сорбционной активности эпителия слизистых полости рта в зависимости от индекса массы тела. Результаты: у обследуемых с ИМТ &gt; 25 ниже сорбционная активность эпителия слизистых ротовой полости, в два раза выше уровень IL-1β в супернатанте ротовой жидкости, а также выше, но в пределах нормы, количество лейкоцитов в периферической крови, чем у лиц с нормальным весом.</p></abstract><trans-abstract xml:lang="en"><p>The purpose of the study: to study features of the sorption activity of the epithelium of the oral mucosa, depending on the body mass index. Results: in subjects with a BMI &gt; 25, the sorption activity of the epithelium of the oral mucosa is lower, the level of IL-1β in the supernatant of the oral fluid is twice as high, and the number of leukocytes in the peripheral blood is higher, but within normal limits, than in persons with normal weight.</p></trans-abstract><kwd-group xml:lang="ru"><kwd>сорбция</kwd><kwd>эпителий</kwd><kwd>ожирение</kwd></kwd-group><kwd-group xml:lang="en"><kwd>Sorption</kwd><kwd>epithelium</kwd><kwd>obesity</kwd></kwd-group><funding-group><funding-statement xml:lang="ru">Работа выполнена в рамках программы фундаментальных научных исследований по теме лаборатории экологической иммунологии Института физиологии природных адаптаций ФГБУН ФИЦКИА УрО РАН, № гос. регистрации 122011300377-5</funding-statement></funding-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Федорин М.М., Ливзан М.А., Гаус О.В. Синдром повышенной эпителиальной проницаемости у больных синдромом раздраженного кишечника, ассоциированным с избыточной массой тела и ожирением // РМЖ. Медицинское обозрение. 2023. 7(7). 424-431. doi:10.32364/2587-6821-2023-7-7-4</mixed-citation><mixed-citation xml:lang="en">Fedorin M.M., Livzan M.A., Gauss O.V. Syndrome of increased epithelial permeability in patients with irritable bowel syndrome associated with overweight and obesity. // Medical Review. 2023. 7(7). 424-431.</mixed-citation></citation-alternatives></ref><ref id="cit2"><label>2</label><citation-alternatives><mixed-citation xml:lang="ru">Deciphering the complex interplay of obesity, epithelial barrier dysfunction, and tight junction remodeling: Unraveling potential therapeutic avenues. / AlMarzooqi S.K. [et al] // Obesity reviews: an official journal of the International Association for the Study of Obesity. 2024. e13766. doi:10.1111/obr.13766</mixed-citation><mixed-citation xml:lang="en">Deciphering the complex interplay of obesity, epithelial barrier dysfunction, and tight junction remodeling: Unraveling potential therapeutic avenues. / AlMarzooqi S.K. [et al] // Obesity reviews: an official journal of the International Association for the Study of Obesity. 2024. e13766. doi:10.1111/obr.13766</mixed-citation></citation-alternatives></ref><ref id="cit3"><label>3</label><citation-alternatives><mixed-citation xml:lang="ru">Experimental Periodontitis Induces Gene Expression of Proinflammatory Cytokines in Liver and White Adipose Tissues in Obesity. / Endo Y. [et al] // J Periodontol. 2010. 81(4). 520–6. doi:10.1902/jop.2009.090574</mixed-citation><mixed-citation xml:lang="en">Experimental Periodontitis Induces Gene Expression of Proinflammatory Cytokines in Liver and White Adipose Tissues in Obesity. / Endo Y. [et al] // J Periodontol. 2010. 81(4). 520–6. doi:10.1902/jop.2009.090574</mixed-citation></citation-alternatives></ref><ref id="cit4"><label>4</label><citation-alternatives><mixed-citation xml:lang="ru">Endocytosis of fluorescent microspheres by human oesophageal epithelial cells: comparison between normal and inflamed tissue. / Hopwood D. [et al] // Gut. 1995. 37(5). 598–602. doi:10.1136/gut.37.5.598</mixed-citation><mixed-citation xml:lang="en">Endocytosis of fluorescent microspheres by human oesophageal epithelial cells: comparison between normal and inflamed tissue. / Hopwood D. [et al] // Gut. 1995. 37(5). 598–602. doi:10.1136/gut.37.5.598</mixed-citation></citation-alternatives></ref><ref id="cit5"><label>5</label><citation-alternatives><mixed-citation xml:lang="ru">Innes N.P., Ogden G.R. A technique for the study of endocytosis in human oral epithelial cells. // Archives of oral biology. 1999. 44(6). 519–523. doi:10.1016/s0003-9969(99)00027-8</mixed-citation><mixed-citation xml:lang="en">Innes N.P., Ogden G.R. A technique for the study of endocytosis in human oral epithelial cells. // Archives of oral biology. 1999. 44(6). 519–523. doi:10.1016/s0003-9969(99)00027-8</mixed-citation></citation-alternatives></ref><ref id="cit6"><label>6</label><citation-alternatives><mixed-citation xml:lang="ru">Progress in oral microbiome related to oral and systemic diseases: An update. / Lee Y.H. [et al] // Diagnostics. 2021. 11(7). 1283. doi:10.3390/diagnostics11071283</mixed-citation><mixed-citation xml:lang="en">Progress in oral microbiome related to oral and systemic diseases: An update. / Lee Y.H. [et al] // Diagnostics. 2021. 11(7). 1283. doi:10.3390/diagnostics11071283</mixed-citation></citation-alternatives></ref><ref id="cit7"><label>7</label><citation-alternatives><mixed-citation xml:lang="ru">The Relationship between the Oral Microbiota and Metabolic Syndrome. / Prince Y. [et al] // Biomedicines. 2023. 11(1). 3. doi:10.3390/biomedicines11010003</mixed-citation><mixed-citation xml:lang="en">The Relationship between the Oral Microbiota and Metabolic Syndrome. / Prince Y. [et al] // Biomedicines. 2023. 11(1). 3. doi:10.3390/biomedicines11010003</mixed-citation></citation-alternatives></ref><ref id="cit8"><label>8</label><citation-alternatives><mixed-citation xml:lang="ru">Differences in compositions of oral and fecal microbiota between patients with obesity and controls. /stefura T. [et al] // Medicina (Lithuania). 2021. 57(7). 678. doi:10.3390/medicina57070678</mixed-citation><mixed-citation xml:lang="en">Differences in compositions of oral and fecal microbiota between patients with obesity and controls. /stefura T. [et al] // Medicina (Lithuania). 2021. 57(7). 678. doi:10.3390/medicina57070678</mixed-citation></citation-alternatives></ref><ref id="cit9"><label>9</label><citation-alternatives><mixed-citation xml:lang="ru">Wall, D.A., Maack, T. Endocytic uptake, transport, and catabolism of proteins by epithelial cells. The American journal of physiology. 1985. 248(1 Pt 1). C12–C20. doi:10.1152/ajpcell.1985.248.1.C12</mixed-citation><mixed-citation xml:lang="en">Wall, D.A., Maack, T. Endocytic uptake, transport, and catabolism of proteins by epithelial cells. The American journal of physiology. 1985. 248(1 Pt 1). C12–C20. doi:10.1152/ajpcell.1985.248.1.C12</mixed-citation></citation-alternatives></ref><ref id="cit10"><label>10</label><citation-alternatives><mixed-citation xml:lang="ru">Zhurakivska O.Y., Atamanchuk O.V. Morphological characteristics of diabetic glossitis. Wiadomosci lekarskie (Warsaw, Poland: 1960). 2022. 75(3). 619–623.</mixed-citation><mixed-citation xml:lang="en">Zhurakivska O.Y., Atamanchuk O.V. Morphological characteristics of diabetic glossitis. Wiadomosci lekarskie (Warsaw, Poland: 1960). 2022. 75(3). 619–623.</mixed-citation></citation-alternatives></ref></ref-list><fn-group><fn fn-type="conflict"><p>The authors declare that there are no conflicts of interest present.</p></fn></fn-group></back></article>
