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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">ymj</journal-id><journal-title-group><journal-title xml:lang="ru">Якутский медицинский журнал</journal-title><trans-title-group xml:lang="en"><trans-title>Yakut Medical Journal</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">1813-1905</issn><issn pub-type="epub">2312-1017</issn><publisher><publisher-name>ЯНЦ КМП</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="doi">10.25789/YMJ.2020.70.29</article-id><article-id custom-type="elpub" pub-id-type="custom">ymj-698</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>ТОЧКА ЗРЕНИЯ</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>POINT OF VIEW</subject></subj-group></article-categories><title-group><article-title>Особенности спектра сенсибилизации при дермато-респираторных проявлениях аллергии у детей Хакасии</article-title><trans-title-group xml:lang="en"><trans-title>Features of the sensitization spectrum in dermato-respiratory manifestations of allergy in children of Khakassia</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0001-5349-9122</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Барило</surname><given-names>А. А.</given-names></name><name name-style="western" xml:lang="en"><surname>Barilo</surname><given-names>A. A.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Барило Анна Александровна – к.м.н., н.с.</p></bio><bio xml:lang="en"><p>Anna A. Barilo - candidate of medical sciences, senior researcher at the Laboratory of Clinical Pathophysiology</p><p>660022, Krasnoyarsk, 660022, Partizan Zheleznyak Str, d.3g; tel .: 89135584020</p></bio><email xlink:type="simple">anntomsk@yandex.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-1197-1481</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Смирнова</surname><given-names>С. В.</given-names></name><name name-style="western" xml:lang="en"><surname>Smirnova</surname><given-names>S. V.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Смирнова Светлана Витальевна – д.м.н., проф., руковод. научного направления</p></bio><bio xml:lang="en"><p>Svetlana V. Smirnova - MD, professor, head of the scientific direction</p><p>660022, Krasnoyarsk, 660022, Partizan Zheleznyak Str, d.3g; tel .: +7 (391) 228-06- 81, +7 (391) 228-06-83</p></bio><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Борисова</surname><given-names>И. В.</given-names></name><name name-style="western" xml:lang="en"><surname>Borisova</surname><given-names>I. V.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Борисова Ирина Васильевна – к.м.н., врач аллерголог-иммунолог</p></bio><bio xml:lang="en"><p>Irina V. Borisova - candidate of medical sciences, doctor allergist-immunologist</p><p>660022, Krasnoyarsk, 660022, 78-Volunteer Brigade Str-21; tel. +79835745520</p></bio><xref ref-type="aff" rid="aff-1"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru">НИИ медицинских проблем Севера - обособленное подразделение ФИЦ КНЦ СО РАН<country>Россия</country></aff><aff xml:lang="en">Scientific Research Institute of Medical Problems of the North – a separate division of the Federal Research Center «Krasnoyarsk Science Center» of the Siberian Branch of the Russian Academy of Sciences<country>Russian Federation</country></aff></aff-alternatives><pub-date pub-type="collection"><year>2020</year></pub-date><pub-date pub-type="epub"><day>17</day><month>05</month><year>2025</year></pub-date><volume>0</volume><issue>2</issue><fpage>99</fpage><lpage>102</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Барило А.А., Смирнова С.В., Борисова И.В., 2025</copyright-statement><copyright-year>2025</copyright-year><copyright-holder xml:lang="ru">Барило А.А., Смирнова С.В., Борисова И.В.</copyright-holder><copyright-holder xml:lang="en">Barilo A.A., Smirnova S.V., Borisova I.V.</copyright-holder><license license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://ymj.elpub.ru/jour/article/view/698">https://ymj.elpub.ru/jour/article/view/698</self-uri><abstract><p>В исследовании проведено изучение особенностей спектра сенсибилизации к пищевым и ингаляционным аллергенам детей Хакасии, больных атопическим дерматитом в сочетании с респираторными проявлениями аллергии, на основании аллергологического анамнеза, данных объективного осмотра и результатов кожного тестирования (prick-тест). Определено, что факторами риска развития дерматореспираторного синдрома у детей с поражением верхних дыхательных путей или полиорганным поражением респираторного тракта могут являться: длительное течение атопического дерматита, манифестация атопического дерматита на 1-м году жизни, отягощенная наследственность, кожный зуд, сезонность заболевания, высокая концентрация общего IgE в сыворотке крови, наличие сенсибилизации к пищевым и пыльцевым аллергенам, поливалентная сенсибилизация к молоку, яйцу, злакам. Проведенное исследование показало, что дети Хакасии имеют особенности спектра сенсибилизации в зависимости от расширения «шоковых» органов атопии от атопического дерматита до дерматореспираторного синдрома.</p></abstract><trans-abstract xml:lang="en"><p>The study examined the characteristics of the spectrum of sensitization to food and inhalant allergens in children of Khakassia with atopic dermatitis in combination with respiratory manifestations of allergies based on allergological history, objective examination data and skin testing results (prick-test). It is defined, that risk factors for the development of dermatorespiratory syndrome in children with upper respiratory tract damage or multiple organ respiratory tract damage may include: long course of the atopic dermatitis, manifestation of atopic dermatitis in the 1st year of life, aggravated heredity, pruritus, seasonality of the disease, high concentration of total IgE in blood serum, the presence of sensitization to food and pollen allergens, multivalent sensitization to milk, egg, cereals. Our study showed that the children of Khakassia have features of the sensitization spectrum depending on the expansion of the “shock” organs of atopy from atopic dermatitis to dermatorespiratory syndrome.</p></trans-abstract><kwd-group xml:lang="ru"><kwd>дерматореспираторный синдром</kwd><kwd>атопический дерматит</kwd><kwd>аллергены</kwd><kwd>сенсибилизация</kwd></kwd-group><kwd-group xml:lang="en"><kwd>dermatorespiratory syndrome</kwd><kwd>atopic dermatitis</kwd><kwd>allergens</kwd><kwd>sensitization</kwd></kwd-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Барило А.А. Дерматореспираторный синдром как проявление пищевой аллергии у детей / А.А. Барило, И.В. Борисова, С.В. Смирнова // Российский аллергологич. ж-л. – 2019. – Т.16, №1-2. – С.32-34.</mixed-citation><mixed-citation xml:lang="en">Barilo A.A. 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