<?xml version="1.0" encoding="UTF-8"?>
<!DOCTYPE article PUBLIC "-//NLM//DTD JATS (Z39.96) Journal Publishing DTD v1.3 20210610//EN" "JATS-journalpublishing1-3.dtd">
<article article-type="review-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">ymj</journal-id><journal-title-group><journal-title xml:lang="ru">Якутский медицинский журнал</journal-title><trans-title-group xml:lang="en"><trans-title>Yakut Medical Journal</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">1813-1905</issn><issn pub-type="epub">2312-1017</issn><publisher><publisher-name>ЯНЦ КМП</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="doi">10.25789/YMJ.2021.76.25</article-id><article-id custom-type="elpub" pub-id-type="custom">ymj-609</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>НАУЧНЫЕ ОБЗОРЫ И ЛЕКЦИИ</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>SCIENTIFIC REVIEWS AND LECTURES</subject></subj-group></article-categories><title-group><article-title>Микробиом кишечника и грудное вскармливание у детей</article-title><trans-title-group xml:lang="en"><trans-title>Gut microbiome and breastfeeding of children</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Саввина</surname><given-names>М. С.</given-names></name><name name-style="western" xml:lang="en"><surname>Savvina</surname><given-names>M. S.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Саввина Майя Семеновна – к.м.н., с.н.с. ЯНЦ КМП</p></bio><bio xml:lang="en"><p>Savvina Maya Semenovna – Candidate of Medical Sciences, senior researcher at the Laboratory for monitoring the health status of children of the YSC CMP</p></bio><email xlink:type="simple">maya_savvina@mail.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Бурцева</surname><given-names>Т. Е.</given-names></name><name name-style="western" xml:lang="en"><surname>Burtseva</surname><given-names>T. E.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Бурцева Татьяна Егоровна – д.м.н., проф. МИ СВФУ им. М.К. Аммосова, в.н.с. -руковод. лаб. ЯНЦ КМП</p></bio><bio xml:lang="en"><p>Burtseva Tatiana Egorovna – MD, Professor of the Department of Pediatrics and Pediatric Surgery of the NEFU MI, head of the lab. monitoring of the health status of children of the YSC CMP</p></bio><email xlink:type="simple">bourtsevat@yandex.ru</email><xref ref-type="aff" rid="aff-2"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Мунхалов</surname><given-names>А. А.</given-names></name><name name-style="western" xml:lang="en"><surname>Munkhalov</surname><given-names>A. A.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Мунхалов Алексей Андреевич – студент ИЗФИР СВФУ им. М.К. Аммосова</p></bio><bio xml:lang="en"><p>Munkhalov Alexey Andreevich – student of APO-19-261 Department of English Philology of the IML NEFU</p></bio><xref ref-type="aff" rid="aff-3"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru"><institution>ЯНЦ КМП</institution><country>Россия</country></aff><aff xml:lang="en"><institution>YSC CMP</institution><country>Russian Federation</country></aff></aff-alternatives><aff-alternatives id="aff-2"><aff xml:lang="ru"><institution>МИ СВФУ им. М.К. Аммосова; ЯНЦ КМП</institution><country>Россия</country></aff><aff xml:lang="en"><institution>NEFU; YSC CMP</institution><country>Russian Federation</country></aff></aff-alternatives><aff-alternatives id="aff-3"><aff xml:lang="ru"><institution>СВФУ им. М.К. Аммосова</institution><country>Россия</country></aff><aff xml:lang="en"><institution>NEFU</institution><country>Russian Federation</country></aff></aff-alternatives><pub-date pub-type="collection"><year>2021</year></pub-date><pub-date pub-type="epub"><day>04</day><month>05</month><year>2025</year></pub-date><volume>0</volume><issue>4</issue><fpage>107</fpage><lpage>109</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Саввина М.С., Бурцева Т.Е., Мунхалов А.А., 2025</copyright-statement><copyright-year>2025</copyright-year><copyright-holder xml:lang="ru">Саввина М.С., Бурцева Т.Е., Мунхалов А.А.</copyright-holder><copyright-holder xml:lang="en">Savvina M.S., Burtseva T.E., Munkhalov A.A.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://ymj.elpub.ru/jour/article/view/609">https://ymj.elpub.ru/jour/article/view/609</self-uri><abstract><p>Представлен обзор литературы по исследованиям микрофлоры кишечника у детей. Исследования, проведенные в течение последних лет, доказывают важность влияния микробиома кишечника на здоровье детей. Приведены современные представления о микробиоме кишечника. Дана краткая характеристика состава микрофлоры кишечника и его воздействие на здоровье ребенка.</p></abstract><trans-abstract xml:lang="en"><p>A review of the literature on studies of the intestinal microflora in children is presented. The research for recent years has demonstrated the importance of the impact of the gut microbiome on children's health. The current understanding of the intestinal microbiome is introduced. A brief description of the composition of the intestinal microflora and its impact on the health of the child is given.</p></trans-abstract><kwd-group xml:lang="ru"><kwd>микрофлора кишечника</kwd><kwd>микробиом кишечника</kwd><kwd>микроб</kwd></kwd-group><kwd-group xml:lang="en"><kwd>microflora intestine</kwd><kwd>microbiome intestine</kwd><kwd>microbe</kwd></kwd-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Баранов А.А. Профилактическая педиатрия – новые вызовы / А.А. Баранов, Л.С. Намазова-Баранова, В.Ю. Альбицкий // Вопросы современной педиатрии. – 2012. – Т.11, №2. – С. 7-10.</mixed-citation><mixed-citation xml:lang="en">Baranov  A.A.  Preventive  pediatrics  - new challenges / Baranov A.A, Namazova-Baranova L.S, Albitsky V.Y. // Issues of modern pediatrics. - 2012. - Vol.11, No. 2. - P. 7-10.</mixed-citation></citation-alternatives></ref><ref id="cit2"><label>2</label><citation-alternatives><mixed-citation xml:lang="ru">Кафарская Л.И. Особенности формирования микрофлоры у детей раннего возраста и пути ее коррекции с помощью пробиотиков / Л.И. Кафарская, М.Л. Шуникова, Б.А. Ефимов // Педиатрическая фармакология. – 2011. – Т.8. – №2. – С. 94-98.</mixed-citation><mixed-citation xml:lang="en">Kafarskaya L.I. Features of microflora formation in young children and ways of its correction with the help of probiotics / Kafarskaya L.I., Shunikova M.L., Efimov B.A. // Pediatric pharmacology. - 2011. - Vol.8. - No. 2. - P. 94-98.</mixed-citation></citation-alternatives></ref><ref id="cit3"><label>3</label><citation-alternatives><mixed-citation xml:lang="ru">Николаева И.В. Кишечная микрофлора у здоровых детей раннего возраста / И.В. Николаева, В.А. Анохин, И.А. Айнутдинова // Российский вестник перинатологии и педиатрии. – 2009. – Т.54, №2. – С. 30-33.</mixed-citation><mixed-citation xml:lang="en">Nikolaeva I.V. Intestinal microflora in healthy young children / Nikolaeva I.V., Anokhin V.A., Ainutdinova I.A. // Russian Bulletin of Perinatology and Pediatrics. - 2009. - Vol.54, No. 2. - P. 30-33.</mixed-citation></citation-alternatives></ref><ref id="cit4"><label>4</label><citation-alternatives><mixed-citation xml:lang="ru">Якушин А.С. Кишечная микробиота: формирование в раннем возрасте, влияние на здоровье, способы коррекции / А.С. Якушин, С.Е. Украинцев, М.Ю. Денисов // Вопросы современной педиатрии. – 2017. - №16(6). – С. 487-492.</mixed-citation><mixed-citation xml:lang="en">Yakushin A.S. Intestinal microbiota: formation at an early age, impact on health, methods of correction / Yakushin A.S., Ukraintsev S.E., Denisov M.Yu. // Issues of modern pediatrics. – 2017. - №16(6). – P. 487-492.</mixed-citation></citation-alternatives></ref><ref id="cit5"><label>5</label><citation-alternatives><mixed-citation xml:lang="ru">Ayechu–Muruzabal V. Diversity of human milk oligosaccharides and effects on early life immune development // V. Ayechu – Muruzabal, A.H. van Stigt, M. Mank [et al.] – 2018.- 6.- 239 p.</mixed-citation><mixed-citation xml:lang="en">Ayechu–Muruzabal V. Diversity of human milk oligosaccharides and effects on early life immune development // V. Ayechu – Muruzabal, A.H. van Stigt, M. Mank [et al.] – 2018.- 6.- 239 p.</mixed-citation></citation-alternatives></ref><ref id="cit6"><label>6</label><citation-alternatives><mixed-citation xml:lang="ru">Azad M.B. Infant feeding and the developmental origins of chronic disease in the child cohort: role of human milk bioactives and gut microbiota // M.B. Azad. – Breastfeed Med. – 2019. – 14. – 22-24 p.</mixed-citation><mixed-citation xml:lang="en">Azad M.B. Infant feeding and the developmental origins of chronic disease in the child cohort: role of human milk bioactives and gut microbiota // M.B. Azad. – Breastfeed Med. – 2019. – 14. – 22-24 p.</mixed-citation></citation-alternatives></ref><ref id="cit7"><label>7</label><citation-alternatives><mixed-citation xml:lang="ru">Best N. On the origin of species: factors shaping the establishment of infants gut microbiota / N. Best, M.W. Hornef, P.H. Savelkoul [et al.] // Birth Defects Res C Embrio Today. – 2015. – 105:240. - 51 p.</mixed-citation><mixed-citation xml:lang="en">Best N. On the origin of species: factors shaping the establishment of infants gut microbiota / N. Best, M.W. Hornef, P.H. Savelkoul [et al.] // Birth Defects Res C Embrio Today. – 2015. – 105:240. - 51 p.</mixed-citation></citation-alternatives></ref><ref id="cit8"><label>8</label><citation-alternatives><mixed-citation xml:lang="ru">Bridgman S.L. Fecal shot-chain fatty acid variations by breastfeeding status in infants at 4 months: differences in relative versus absolute concentrations // S.L. Bridgman, M.B. Azad, C.J. Field [et al.] – 2017. – 4:11.</mixed-citation><mixed-citation xml:lang="en">Bridgman S.L. Fecal shot-chain fatty acid variations by breastfeeding status in infants at 4 months: differences in relative versus absolute concentrations // S.L. Bridgman, M.B. Azad, C.J. Field [et al.] – 2017. – 4:11.</mixed-citation></citation-alternatives></ref><ref id="cit9"><label>9</label><citation-alternatives><mixed-citation xml:lang="ru">Chernikova D.A. Fetal exposures and perinatal influences on the stool microbiota of premature infants / D.A. Chernikova, D.C. Koestler, A.G. Hoen [et al.] // J. Matern. Fetal. Neonatal. Med. – 2016. – 29: 99-105 p.</mixed-citation><mixed-citation xml:lang="en">Chernikova D.A. Fetal exposures and perinatal influences on the stool microbiota of premature infants / D.A. Chernikova, D.C. Koestler, A.G. Hoen [et al.] // J. Matern. Fetal. Neonatal. Med. – 2016. – 29: 99-105 p.</mixed-citation></citation-alternatives></ref><ref id="cit10"><label>10</label><citation-alternatives><mixed-citation xml:lang="ru">David L.A. Diet rapidly and reproducibly alters the human gut microbiome / L.A. David, C.F. Maurice, R.N. Carmody [et al.] // Nature. – 2014. – 505: 559-563 p.</mixed-citation><mixed-citation xml:lang="en">David L.A. Diet rapidly and reproducibly alters the human gut microbiome / L.A. David, C.F. Maurice, R.N. Carmody [et al.] // Nature. – 2014. – 505: 559-563 p.</mixed-citation></citation-alternatives></ref><ref id="cit11"><label>11</label><citation-alternatives><mixed-citation xml:lang="ru">Dror D.K. Overview of Nutrients in Human Milk // D.K. Dror, L.H. Allen. - 2018. - №9. – 278-294 p.</mixed-citation><mixed-citation xml:lang="en">Dror D.K. Overview of Nutrients in Human Milk // D.K. Dror, L.H. Allen. - 2018. - №9. – 278-294 p.</mixed-citation></citation-alternatives></ref><ref id="cit12"><label>12</label><citation-alternatives><mixed-citation xml:lang="ru">Forbes J.D. Association of exposure to formula in the hospital and subsequent infant feeding practices with gut microbiota and risk of overweight in the first year of life // J.D. Forbes, M.B. Azad, L. Vehling [et al.] – JAMA Pediatr. – 2018. – 172 p.</mixed-citation><mixed-citation xml:lang="en">Forbes J.D. Association of exposure to formula in the hospital and subsequent infant feeding practices with gut microbiota and risk of overweight in the first year of life // J.D. Forbes, M.B. Azad, L. Vehling [et al.] – JAMA Pediatr. – 2018. – 172 p.</mixed-citation></citation-alternatives></ref><ref id="cit13"><label>13</label><citation-alternatives><mixed-citation xml:lang="ru">Gay M. Worldwide variation in human milk metabolome: Indicators of breast physiology and maternal lifestyle? // M. Gay, P. Koleva, C. Slupsky [et al.] – Nutrients. – 2018. - № 10. – 1151 p.</mixed-citation><mixed-citation xml:lang="en">Gay M. Worldwide variation in human milk metabolome: Indicators of breast physiology and maternal lifestyle? // M. Gay, P. Koleva, C. Slupsky [et al.] – Nutrients. – 2018. - № 10. – 1151 p.</mixed-citation></citation-alternatives></ref><ref id="cit14"><label>14</label><citation-alternatives><mixed-citation xml:lang="ru">Gensollen T. How colonization by microbiotain early life shapes the immune system / T. Gensollen, S.S. Iyer, D.L. Kasper // Science. – 2016. – 352:539 – 44 p.</mixed-citation><mixed-citation xml:lang="en">Gensollen T. How colonization by microbiotain early life shapes the immune system / T. Gensollen, S.S. Iyer, D.L. Kasper // Science. – 2016. – 352:539 – 44 p.</mixed-citation></citation-alternatives></ref><ref id="cit15"><label>15</label><citation-alternatives><mixed-citation xml:lang="ru">Gomez-Gallego C. Human breast milk NMR metabolomic profile across specific geographical locations and its association with the milk microbiota // Nutrients. – 2018. – 10: 1355 p.</mixed-citation><mixed-citation xml:lang="en">Gomez-Gallego C. Human breast milk NMR  metabolomic  profile  across  specific geographical locations and its association with the milk microbiota // Nutrients. – 2018. – 10: 1355 p.</mixed-citation></citation-alternatives></ref><ref id="cit16"><label>16</label><citation-alternatives><mixed-citation xml:lang="ru">Lavin T. Investigating caesarean section birth as a risk factor for childhood overweight / T. Lavin, D.B. Preen // Child. Obes. – 2018. – 14: 131-138 p.</mixed-citation><mixed-citation xml:lang="en">Lavin T. Investigating caesarean section birth as a risk factor for childhood overweight / T. Lavin, D.B. Preen // Child. Obes. – 2018. – 14: 131-138 p.</mixed-citation></citation-alternatives></ref><ref id="cit17"><label>17</label><citation-alternatives><mixed-citation xml:lang="ru">Li H. Impact of maternal intrapartum antibiotics on the initial oral microbiome of neonates // H. Li, B Xiao, Y. Zhang [et al.] – J. Pediatr. Neonatal. – 2019. - № 60. – 654-661 p.</mixed-citation><mixed-citation xml:lang="en">Li H. Impact of maternal intrapartum antibiotics on the initial oral microbiome of neonates // H. Li, B Xiao, Y. Zhang [et al.] – J. Pediatr. Neonatal. – 2019. - № 60. – 654-661 p.</mixed-citation></citation-alternatives></ref><ref id="cit18"><label>18</label><citation-alternatives><mixed-citation xml:lang="ru">Miliku K. Human milk oligosaccharide profiles and food sensitization among infants in the child study // K. Miliki, B. Robertson, A.K. Sharma [et al.] – Allergy. - 2018. – 73: 2070. – 3 p.</mixed-citation><mixed-citation xml:lang="en">Miliku K. Human milk oligosaccharide profiles and food sensitization among infants in the child study // K. Miliki, B. Robertson, A.K. Sharma [et al.] – Allergy. - 2018. – 73: 2070. – 3 p.</mixed-citation></citation-alternatives></ref><ref id="cit19"><label>19</label><citation-alternatives><mixed-citation xml:lang="ru">Moossavi S. Composition and variation of the human milk microbiota are influenced by maternal and early-life factors // S. Moossavi, S. Sepehri, B. Robertson [et al.] – J. Cell. Host. Microbe. – 2019. - № 25. – 324-335 p.</mixed-citation><mixed-citation xml:lang="en">Moossavi S. Composition and variation of the human milk microbiota are influenced by maternal and early-life factors // S. Moossavi, S. Sepehri, B. Robertson [et al.] – J. Cell. Host. Microbe. – 2019. - № 25. – 324-335 p.</mixed-citation></citation-alternatives></ref><ref id="cit20"><label>20</label><citation-alternatives><mixed-citation xml:lang="ru">Ho T.T.B. Dichotomous development of the gut microbiome in preterm infants / T.T.B. Ho, M.W. Groer, B.Kane [et al.] // Microbiome. – 2018. – 6:157 p.</mixed-citation><mixed-citation xml:lang="en">Ho T.T.B. Dichotomous development of the gut microbiome in preterm infants / T.T.B. Ho, M.W. Groer, B.Kane [et al.] // Microbiome. – 2018. – 6:157 p.</mixed-citation></citation-alternatives></ref><ref id="cit21"><label>21</label><citation-alternatives><mixed-citation xml:lang="ru">Perez-Munoz M.E. A critical assessment of the “sterile womb” and “in utero colonization” hypotheses: Implications for research on the pioneer infant micribiome / M.E. Perez-Munoz, M.-C. Arrieta, A.E. Ramer-Tait, J. Walter // Microbiome. – 2017.- 5: 48 p.</mixed-citation><mixed-citation xml:lang="en">Perez-Munoz M.E. A critical assessment of the “sterile womb” and “in utero colonization” hypotheses: Implications for research on the pioneer infant micribiome / M.E. Perez-Munoz, M.-C. Arrieta, A.E. Ramer-Tait, J. Walter // Microbiome. – 2017.- 5: 48 p.</mixed-citation></citation-alternatives></ref><ref id="cit22"><label>22</label><citation-alternatives><mixed-citation xml:lang="ru">Rosenbauer J. Early infant feeding and risk of type 1 diabetes mellitus – a nationwide population-based case-control study in pre-school children // Diabetes Metab. Res.Rev. – 2018.- 24:211.- 222 p.</mixed-citation><mixed-citation xml:lang="en">Rosenbauer J. Early infant feeding and risk of type 1 diabetes mellitus – a nationwide population-based case-control study in pre-school children // Diabetes Metab. Res.Rev. – 2018.- 24:211.- 222 p.</mixed-citation></citation-alternatives></ref><ref id="cit23"><label>23</label><citation-alternatives><mixed-citation xml:lang="ru">Sato Y. Maternal gut microbiota is associated with newborn anthropometrics in a sex-specific manner // Y. Sato, K. Sakurai, H. Tanabe [et al.] – J. Dev. Orig. Health Dis. – 2019. - № 10. – P. 659-666.</mixed-citation><mixed-citation xml:lang="en">Sato Y. Maternal gut microbiota is associated with newborn anthropometrics in a sex-specific manner // Y. Sato, K. Sakurai, H. Tanabe [et al.] – J. Dev. Orig. Health Dis. – 2019. - № 10. – P. 659-666.</mixed-citation></citation-alternatives></ref><ref id="cit24"><label>24</label><citation-alternatives><mixed-citation xml:lang="ru">Sila S. Altered gut microbiota is present in newly diagnosed pediatric patients with inflammatory bowel disease / S. Sila, M. Jelic, I. Trivic [et al.] // J. Pediatr. Gastroenterol. Nutr. – 2020. – № 70.- P. 495-502.</mixed-citation><mixed-citation xml:lang="en">Sila S. Altered gut microbiota is present in newly diagnosed pediatric patients with inflammatory bowel disease / S. Sila, M. Jelic, I. Trivic [et al.] // J. Pediatr. Gastroenterol. Nutr. – 2020. – № 70.- P. 495-502.</mixed-citation></citation-alternatives></ref><ref id="cit25"><label>25</label><citation-alternatives><mixed-citation xml:lang="ru">Tamburirni S. The microbiome in early life: implications for health outcomes / S. Tamburini, N. Shen, H.C. Wu [et al.] // Nat. Med. – 2016. – 22:713 – 22 p.</mixed-citation><mixed-citation xml:lang="en">Tamburirni S. The microbiome in early life: implications for health outcomes / S. Tamburini, N. Shen, H.C. Wu [et al.] // Nat. Med. – 2016. – 22:713 – 22 p.</mixed-citation></citation-alternatives></ref><ref id="cit26"><label>26</label><citation-alternatives><mixed-citation xml:lang="ru">Triantis V. Immunological effects of human milk oligosaccharides / V. Triantis, L. Bode, R.J.J. van Neerven // Front. Pediatr. 2018. – 6: 190 p.</mixed-citation><mixed-citation xml:lang="en">Triantis V. Immunological effects of human milk oligosaccharides / V. Triantis, L. Bode, R.J.J. van Neerven // Front. Pediatr. 2018. – 6: 190 p.</mixed-citation></citation-alternatives></ref><ref id="cit27"><label>27</label><citation-alternatives><mixed-citation xml:lang="ru">Twigger A.-J. Expression of granulisyn, perforin and granzymes in human milk over lactation and in the case of maternal infection // A.-J. Twigger, G. Kuffer, D. Geddes [et al.] – Nutrients. – 2018. - № 10. – 1230 p.</mixed-citation><mixed-citation xml:lang="en">Twigger A.-J. Expression of granulisyn, perforin and granzymes in human milk over lactation and in the case of maternal infection // A.-J. Twigger, G. Kuffer, D. Geddes [et al.] – Nutrients. – 2018. - № 10. – 1230 p.</mixed-citation></citation-alternatives></ref><ref id="cit28"><label>28</label><citation-alternatives><mixed-citation xml:lang="ru">Unger S. Gut microbiota of the very-low-birth-weight infant / S. Unger, A. Stintzi, P. Shah [et al.] // Pediatr. Res. – 2015. – 77:205 - 213 p.</mixed-citation><mixed-citation xml:lang="en">Unger S. Gut microbiota of the very-low-birth-weight infant / S. Unger, A. Stintzi, P. Shah [et al.] // Pediatr. Res. – 2015. – 77:205 - 213 p.</mixed-citation></citation-alternatives></ref><ref id="cit29"><label>29</label><citation-alternatives><mixed-citation xml:lang="ru">Yatsunenko T. Human gut microbiome viewed across age and geography / T. Yatsunenko, F.E. Rey, M.J. Manary [et al.] // Nature. – 2012. – 486. – P. 222-227.</mixed-citation><mixed-citation xml:lang="en">Yatsunenko T. Human gut microbiome viewed across age and geography / T. Yatsunenko, F.E. Rey, M.J. Manary [et al.] // Nature. – 2012. – 486. – P. 222-227.</mixed-citation></citation-alternatives></ref></ref-list><fn-group><fn fn-type="conflict"><p>The authors declare that there are no conflicts of interest present.</p></fn></fn-group></back></article>
