ymjЯкутский медицинский журналYakut Medical Journal1813-19052312-1017ЯНЦ КМП10.25789/YMJ.2021.75.20ymj-547Research ArticleАРКТИЧЕСКАЯ МЕДИЦИНАARCTIC MEDICINEПоиск ассоциации полиморфного маркера a1166c гена AGTR1 (rs5186) с эссенциальной гипертензией у коренных этнических групп ЯкутииSearch for the association of the a1166c polymorphic marker of the AGTR1 (rs5186) genehttps://orcid.org/0000-0003-0010-9850СофроноваС. И.SofronovaS. I.

Софронова Саргылана Ивановна – к.м.н., гл.н.с. – руковод. Отдела

Sofronova Sargylana Ivanovna - PHD, Leading researcher of YSC CMP

sara2208@mail.ruКлимоваТ. М.KlimovaT. M.

Климова Татьяна Михайловна – к.м.н., с.н.с.; доцент Медицинского института

Klimova Tatyana Mikhailovna - PHD, researcher of YSC CMP, assistant professor of Institute of Medicine

КириллинаМ. П.KirillinaM. P.

Кириллина Мария Петровна – к.б.н., в.н.с. – руковод. лаб.

Kirillina Maria Petrovna - PhD, Leading Researcher of YSC CMP

https://orcid.org/0000-0002-9243-6623КононоваИ. В.KononovaI. V.

Кононова Ирина Васильевна – к.м.н., с.н.с.

Kononova Irina Vasilievna - PHD, researcher of YSC CMP

irinakon.07@mail.ruhttps://orcid.org/0000-0002-4817-5315РомановаА. Н.RomanovaA. N.

Романова Анна Николаевна – д.м.н., директор

Romanova Anna Nikolaevna - MD, director of YSC CMP

Якутский научный центра комплексных медицинских проблемРоссияYakut science centre of complex medical problemsRussian FederationСВФУ им. М.К. АммосоваРоссияM.K. Ammosov NEFURussian Federation202127042025037680Copyright © Софронова С.И., Климова Т.М., Кириллина М.П., Кононова И.В., Романова А.Н., 20252025Софронова С.И., Климова Т.М., Кириллина М.П., Кононова И.В., Романова А.Н.Sofronova S.I., Klimova T.M., Kirillina M.P., Kononova I.V., Romanova A.N.Данная работа распространяется под лицензией Creative Commons Attribution 4.0.This work is licensed under a Creative Commons Attribution 4.0 License.https://ymj.elpub.ru/jour/article/view/547

Проведен поиск возможной связи между полиморфным маркером A1166C гена AGTR1 (rs5186) и эссенциальной гипертензией в группе представителей коренных этнических групп Якутии (якуты, чукчи, юкагиры, эвены). Ассоциативная связь между полиморфным маркером A1166C гена AGTR1 (rs5186) и эссенциальной гипертензией в исследуемой популяции не обнаружена.

The search was carried out for a possible connection between the polymorphic marker A1166C of the AGTR1 gene (rs5186) and essential hypertension in the group of representatives of the indigenous ethnic groups of Yakutia (Yakuts, Chukchi, Yukaghirs, Evens). No association was found between the polymorphic marker A1166C of the gene AGTR1 (rs5186) and essential hypertension in the study population.

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The authors declare that there are no conflicts of interest present.