ymjЯкутский медицинский журналYakut Medical Journal1813-19052312-1017ЯНЦ КМП10.25789/YMJ.2021.73.28ymj-522Research ArticleНАУЧНЫЕ ОБЗОРЫ И ЛЕКЦИИSCIENTIFIC REVIEWS AND LECTURESБиологические микрочипы в практической медицине и перспективы их применения как инструмента для скрининговых программBiological microchips in practical medicine and the prospects for their application as a screening toolСаввинаМ. Т.SavvinaM. T.

Саввина Мира Таиржановна – н.с.

Savvina Mira Tairzhanovna - research assistant, Scientific research lab.

mira@savv.inМаксимоваН. Р.MaksimovaN. R.

Максимова Надежда Романовна – д.м.н., руководитель

Maksimova Nadezhda Romanovna - MD, head of Scientific research lab.

Науч.-иссл. лаб. МИ СВФУ им. М.К. АммосоваРоссияMedical Institute M.K. Ammosov NEFURussian Federation20212704202501105110Copyright © Саввина М.Т., Максимова Н.Р., 20252025Саввина М.Т., Максимова Н.Р.Savvina M.T., Maksimova N.R.Данная работа распространяется под лицензией Creative Commons Attribution 4.0.This work is licensed under a Creative Commons Attribution 4.0 License.https://ymj.elpub.ru/jour/article/view/522

В данном обзоре литературы представлены современные данные о методах диагностики с использованием биологических микрочипов в различных областях практической медицины. Предложено и аргументировано использование метода, основанного на технологии ДНК-микрочипов, для проведения массового молекулярно-генетического скрининга гетерозиготного носительства наследственных заболеваний.

This literature review presents modern data on diagnostic methods using biological microchips in various fields of practical medicine. The use of the method based on DNA microarray technology for carrying out mass molecular genetic screening of heterozygous carriage of hereditary diseases has been considered.

наследственные заболеваниямолекулярно-генетический скринингбиологические микрочипыпрактическая медицинаhereditary diseasesmolecular genetic screeningbiological microchipspractical medicineРабота выполнена в рамках госзадания Минобрнауки РФ (проект FSRG-2020-0014: «Геномика Арктики: эпидемиология, наследственность и патология».The research is conducted under the state target program: project FSRG2020-0014 “Genomic of Arctic: epidemiology, hereditary and pathologyReferencesТехнология гидрогелевых биочипов и ее применение в медицинской лабораторной диагностике/ Д.А. Грядунов, Д.В. Зименков, В.М. Михайлович [и др.] // 2009. – Лаборатория. - Т.3 (11). – С.. 10-14. A.Hydrogel biochip technology and its application in medical laboratory diagnostics / D.A. Gryadunov, D.V. Zimenkov, V.M. Mikhailovich [et al.] 2009. - Laboratoriya. vol. 3 (11). - P. 10-14. (In Russ.).]Технология гидрогелевых биочипов ИМБ РАН: 30 лет спустя / Д.А. Грядунов, Б.Л. Шаскольски, Т.В. 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The authors declare that there are no conflicts of interest present.