ymjЯкутский медицинский журналYakut Medical Journal1813-19052312-1017ЯНЦ КМП10.25789/YMJ.2024.87.02ymj-4Research ArticleОРИГИНАЛЬНЫЕ ИССЛЕДОВАНИЯORIGINAL RESEARCH15-летний риск развития колоректального рака: прогностическая значимость факторов риска хронических неинфекционных заболеваний при старенииThe 15-year risk of colorectal cancer: prognostic significance of risk factors for chronic non-communicable diseases with aginghttps://orcid.org/0000-0002-3828-1077НикитенкоТ. М.NikitenkoT. M.

Никитенко Татьяна Михайловна – к.м.н., с.н.с.

Nikitenko Tatyana Mikhailovna – Candidate of Medical Sciences, Senior Researcher.

t_nikitenko_72@mail.ruhttps://orcid.org/0000-0001-9270-9188ЩербаковаЛ. В.ShcherbakovaL. V.

Щербакова Лилия Валерьевна – с.н.с.

https://orcid.org/0000-0003-4095-0169РымарО. Д.RymarO. D.

Рымар Оксана Дмитриевна – д.м.н., гл.н.с., зав. лаб.

Rymar Oksana Dmitrievna – MD, PhD, Head of the Scientific Department, Head of the Laboratory.

ФурсовС. А.FursovS. A.

Фурсов Сергей Александрович – д.м.н., проф., гл. онколог Новосибирской области, гл. врач Новосибирского обл. клинич. онкологич. диспансера.

Fursov Sergey Alexandrovich – MD, Professor, Chief oncologist of the Novosibirsk region, Chief physician of the Novosibirsk regional clinic. oncological dispensary.

https://orcid.org/0000-0001-6539-0466МалютинаС. К.MalyutinaS. K.

Малютина Софья Константиновна – д.м.н., проф., зав. лаб.

Malyutina Sofya Konstantinovna – MD, Professor, Head of the Laboratory

НИИТПМ — филиал Ин-та цитологии и генетики СО РАНRussian FederationНИИТПМ — филиал Ин-та цитологии и генетики СО РАНРоссияNovosibirsk regional clinic. oncological dispensaryRussian Federation202402022025031017Copyright © Никитенко Т.М., Щербакова Л.В., Рымар О.Д., Фурсов С.А., Малютина С.К., 20252025Никитенко Т.М., Щербакова Л.В., Рымар О.Д., Фурсов С.А., Малютина С.К.Nikitenko T.M., Shcherbakova L.V., Rymar O.D., Fursov S.A., Malyutina S.K.Данная работа распространяется под лицензией Creative Commons Attribution 4.0.This work is licensed under a Creative Commons Attribution 4.0 License.https://ymj.elpub.ru/jour/article/view/4

С целью изучения прогностической значимости факторов риска хронических неинфекционных заболеваний в развитии колоректального рака (КРР) у людей старшего возраста проведено исследование в популяционной когорте 45-69 лет. Выявлено, что 15-летний риск развития КРР у мужчин был выше, чем у женщин. Риск КРР был положительно ассоциирован с возрастом как у мужчин, так и у женщин. Положительная семейная история злокачественных новообразований любой локализации увеличивала риск развития КРР у мужчин, а наличие сахарного диабета 2 – у женщин.

In order to study the prognostic importance of risk factors of chronic non-communicable diseases in the development of colorectal cancer (CRC) in older people, a study was conducted in a population cohort 45-69 years. It was found that the 15-year risk of developing CRC was higher in men compared to women. CRC risk was positively associated with age in both men and women. A positive family history of malignant neoplasms of any location increased the risk of developing colorectal cancer in men, and the presence of type 2 diabetes mellitus in women.

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The authors declare that there are no conflicts of interest present.