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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">ymj</journal-id><journal-title-group><journal-title xml:lang="ru">Якутский медицинский журнал</journal-title><trans-title-group xml:lang="en"><trans-title>Yakut Medical Journal</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">1813-1905</issn><issn pub-type="epub">2312-1017</issn><publisher><publisher-name>ЯНЦ КМП</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="doi">10.25789/YMJ.2026.95.35</article-id><article-id custom-type="elpub" pub-id-type="custom">ymj-3515</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>СЛУЧАЙ ИЗ ПРАКТИКИ</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>CLINICAL CASE</subject></subj-group></article-categories><title-group><article-title>Болезнь Кавасаки: опыт диагностики и лечения</article-title><trans-title-group xml:lang="en"><trans-title>Kawasaki disease: experience in diagnosis and treatment</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0001-8507-6968</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Саввина</surname><given-names>М. С.</given-names></name><name name-style="western" xml:lang="en"><surname>Savvina</surname><given-names>M. S.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Саввина Майя Семеновна – канд. мед. наук, ст. науч. сотр. </p><p>ул. Кирова, 7, г. Якутск, 677018</p></bio><email xlink:type="simple">maya_savvina@mail.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0009-0002-7274-5354</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Аргунова</surname><given-names>В. М.</given-names></name><name name-style="western" xml:lang="en"><surname>Argunova</surname><given-names>V. M.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Аргунова Вера Маична ‒ врач-ревматолог; главный внештатный ревматолог ДВФО </p><p>Сергеляхское ш., 4, г. Якутск, 677010</p></bio><xref ref-type="aff" rid="aff-2"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0009-0006-4349-1593</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Андреева</surname><given-names>Н. А.</given-names></name><name name-style="western" xml:lang="en"><surname>Andreeva</surname><given-names>N. A.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Андреева Нарыйана Андреевна – студент Медицинского института  </p><p>ул. Кулаковского, 36, г. Якутск, 677000</p></bio><xref ref-type="aff" rid="aff-3"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0009-0003-1753-9221</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Адамова</surname><given-names>Н. А.</given-names></name><name name-style="western" xml:lang="en"><surname>Adamova</surname><given-names>N. A.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Адамова Нарыйаана Афанасьевна ‒ студент Медицинского института  </p><p>ул. Кулаковского, 36, г. Якутск, 677000</p></bio><xref ref-type="aff" rid="aff-3"/></contrib></contrib-group><aff xml:lang="ru" id="aff-1"><institution>ФГБНУ «Якутский научный центр комплексных медицинских проблем»</institution><country>Russian Federation</country></aff><aff xml:lang="ru" id="aff-2"><institution>ГАУ РС(Я) «Республиканская больница №1 – Национальный центр медицины им. М.Е. Николаева»</institution><country>Russian Federation</country></aff><aff xml:lang="ru" id="aff-3"><institution>Медицинский институт ФГАОУ ВО «Северо-Восточный федеральный университет им. М.К. Аммосова»</institution><country>Russian Federation</country></aff><pub-date pub-type="collection"><year>2026</year></pub-date><pub-date pub-type="epub"><day>15</day><month>10</month><year>2026</year></pub-date><volume>0</volume><issue>3</issue><fpage>165</fpage><lpage>168</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Саввина М.С., Аргунова В.М., Андреева Н.А., Адамова Н.А., 2026</copyright-statement><copyright-year>2026</copyright-year><copyright-holder xml:lang="ru">Саввина М.С., Аргунова В.М., Андреева Н.А., Адамова Н.А.</copyright-holder><copyright-holder xml:lang="en">Savvina M.S., Argunova V.M., Andreeva N.A., Adamova N.A.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://ymj.elpub.ru/jour/article/view/3515">https://ymj.elpub.ru/jour/article/view/3515</self-uri><abstract><p>В статье представлен клинический случай полной формы болезни Кавасаки у 4-месячного ребенка, осложненный гемофагоцитарным синдромом и правосторонней нижнедолевой внебольничной пневмонией с нетяжелым течением. Болезнь Кавасаки – это системный васкулит, преимущественно встречающийся у детей до 5 лет. Обсуждается соответствие клинической картины, лабораторных и инструментальных данных диагнозу. Данное заболевание требует изучения и внимания со стороны врачей разных специальностей.</p></abstract><trans-abstract xml:lang="en"><p>The article present a clinical case of a complete form of Kawasaki disease in 4-month-old child, complicated by hemophagocytic syndrome and right-sided lower lobe community-acquired pneumonia with a mild course. Kawasaki disease is a systemic vasculitis predominantly found in children under 5 years of age. The correspondence of the clinical picture, laboratory and instrumental data to the diagnosis is discussed. This disease requires study and attention from doctors of different specialities.</p></trans-abstract><kwd-group xml:lang="ru"><kwd>болезнь Кавасаки</kwd><kwd>коронарные сосуды</kwd><kwd>лихорадка</kwd><kwd>дети</kwd></kwd-group><kwd-group xml:lang="en"><kwd>Kawasaki disease</kwd><kwd>coronary vessels</kwd><kwd>fever</kwd><kwd>children</kwd></kwd-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Баранов А.А. Обзор клинических рекомендаций по болезни/синдрому Кавасаки // Педиатрическая фармакология. 2017; 14 (2): 87-99</mixed-citation><mixed-citation xml:lang="en">Baranov A.A. Review of clinical guidelines for Kawasaki disease/syndrome. Pediatric Pharmacology. 2017; 14(2): 87-99 (in Russian).</mixed-citation></citation-alternatives></ref><ref id="cit2"><label>2</label><citation-alternatives><mixed-citation xml:lang="ru">Rife E, Gedalia A. Kawasaki disease: an update. Curr Rheumatol Rep. 2020; 22: 75, DOI: 10.1007/s11926-020-00941-4. [DOI] [PMC free article] [PubMed] [Google Scholar]</mixed-citation><mixed-citation xml:lang="en">Rife E, Gedalia A. Kawasaki disease: an update. Curr Rheumatol Rep. 2020; 22: 75, DOI: 10.1007/s11926-020-00941-4. [DOI] [PMC free article] [PubMed] [Google Scholar]</mixed-citation></citation-alternatives></ref><ref id="cit3"><label>3</label><citation-alternatives><mixed-citation xml:lang="ru">Бакланов М.А. Оценка клинико-лабораторных показателей синдрома Кавасаки в детском возрасте. Российский педиатрический журнал. 2025;6(1):9</mixed-citation><mixed-citation xml:lang="en">Baklanov M.A. Assessment of clinical and laboratory parameters of Kawasaki syndrome in childhood. Russian Pediatric Journal. 2025;6(1):9 (in Russian).</mixed-citation></citation-alternatives></ref><ref id="cit4"><label>4</label><citation-alternatives><mixed-citation xml:lang="ru">Majerova L., Olejnik P., Vrsanska V. Diagnosis and treatment of Kawasaki disease in children and its coronary complications. Pediatr Prax. 2018; 19(5): 224–228. https://doi.org/10.21508/1027-4065-2020-65-6-122-128</mixed-citation><mixed-citation xml:lang="en">Majerova L., Olejnik P., Vrsanska V. Diagnosis and treatment of Kawasaki disease in children and its coronary complications. Pediatr Prax. 2018; 19(5): 224–228. https://doi.org/10.21508/1027-4065-2020-65-6-122-128</mixed-citation></citation-alternatives></ref><ref id="cit5"><label>5</label><citation-alternatives><mixed-citation xml:lang="ru">Маккриндл Б.В., Роули А.Х., Ньюбергер Дж.В. и др. Диагностика, лечение и долгосрочное ведение болезни Кавасаки: научное заявление для медицинских работников от Американской кардиологической ассоциации</mixed-citation><mixed-citation xml:lang="en">McCrindle B.W., Rowley A.H., Newburger J.W., et al. Diagnosis, treatment and long-term management of Kawasaki disease: a scientific statement for health professionals from the American Heart Association. Circulation. 2017; 135: e927–e999, DOI: 10.1161/CIR.0000000000000484. [ DOI ] [ PubMed ] [ Google Scholar ]</mixed-citation></citation-alternatives></ref><ref id="cit6"><label>6</label><citation-alternatives><mixed-citation xml:lang="ru">Vervoort D., Donne M., Van Gysel D. Pitfalls in the diagnosis and management of Kawasaki disease: An update for the pediatric dermatologist. Pediatr Dermatol. 2018; 35(6): 743-747. DOI: 10.1111/pde.13620.</mixed-citation><mixed-citation xml:lang="en">Vervoort D., Donne M., Van Gysel D. Pitfalls in the diagnosis and management of Kawasaki disease: An update for the pediatric dermatologist. Pediatr Dermatol. 2018; 35(6): 743-747. DOI: 10.1111/pde.13620.</mixed-citation></citation-alternatives></ref><ref id="cit7"><label>7</label><citation-alternatives><mixed-citation xml:lang="ru">Jindal A.K. et al. Non-Exudative conjunctival injection with limbal sparing: a pathognomonic clinical sign of Kawasaki disease. J. Clin. Rheumatol. 2020; 26(3): 59-60. DOI: 10.1097/RHU0000000000000883.</mixed-citation><mixed-citation xml:lang="en">Jindal A.K. et al. Non-Exudative conjunctival injection with limbal sparing: a pathognomonic clinical sign of Kawasaki disease. J. Clin. Rheumatol. 2020; 26(3): 59-60. DOI: 10.1097/RHU0000000000000883.</mixed-citation></citation-alternatives></ref><ref id="cit8"><label>8</label><citation-alternatives><mixed-citation xml:lang="ru">Matsubara T. Infliximab for the treatment of Kawasaki disease. Pediatr Int. 2018; 60(9): 775. DOI: 10.1111/ped.13663.</mixed-citation><mixed-citation xml:lang="en">Matsubara T. Infliximab for the treatment of Kawasaki disease. Pediatr Int. 2018; 60(9): 775. DOI: 10.1111/ped.13663.</mixed-citation></citation-alternatives></ref><ref id="cit9"><label>9</label><citation-alternatives><mixed-citation xml:lang="ru">Tsuda E., Singhal M. Role of imaging studies in Kawasaki disease. Int. J. Rheum Dis. 2018; 21(1): 56-63. DOI: 10.1111/1756-185X.13210.</mixed-citation><mixed-citation xml:lang="en">Tsuda E., Singhal M. Role of imaging studies in Kawasaki disease. Int. J. Rheum Dis. 2018; 21(1): 56-63. DOI: 10.1111/1756-185X.13210.</mixed-citation></citation-alternatives></ref><ref id="cit10"><label>10</label><citation-alternatives><mixed-citation xml:lang="ru">Miyata K. et al. Efficacy and safety of intravenous immunoglobulin plus prednisolone therapy in patients with Kawasaki disease: a multicenter, prospective cohort study. Lanset Child Adolesc. Health. 2018; 2(12): 855-862. DOI: 10.1016/S2352-4642(18) 30293-1.</mixed-citation><mixed-citation xml:lang="en">Miyata K. et al. Efficacy and safety of intravenous immunoglobulin plus prednisolone therapy in patients with Kawasaki disease: a multicenter, prospective cohort study. Lanset Child Adolesc. Health. 2018; 2(12): 855-862. DOI: 10.1016/S2352-4642(18) 30293-1.</mixed-citation></citation-alternatives></ref><ref id="cit11"><label>11</label><citation-alternatives><mixed-citation xml:lang="ru">Singh S., Jindal A.K., Pilania R.K. Diagnosis of Kawasaki disease. Int. J. Rheum Dis. 2018; 21(1): 36-44. Doi: org /10.1111/1756-185X.13224.</mixed-citation><mixed-citation xml:lang="en">Singh S., Jindal A.K., Pilania R.K. Diagnosis of Kawasaki disease. Int. J. Rheum Dis. 2018; 21(1): 36-44. Doi: org /10.1111/1756-185X.13224.</mixed-citation></citation-alternatives></ref></ref-list><fn-group><fn fn-type="conflict"><p>The authors declare that there are no conflicts of interest present.</p></fn></fn-group></back></article>
