<?xml version="1.0" encoding="UTF-8"?>
<!DOCTYPE article PUBLIC "-//NLM//DTD JATS (Z39.96) Journal Publishing DTD v1.3 20210610//EN" "JATS-journalpublishing1-3.dtd">
<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">ymj</journal-id><journal-title-group><journal-title xml:lang="ru">Якутский медицинский журнал</journal-title><trans-title-group xml:lang="en"><trans-title>Yakut Medical Journal</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">1813-1905</issn><issn pub-type="epub">2312-1017</issn><publisher><publisher-name>ЯНЦ КМП</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="doi">10.25789/YMJ.2023.83.32</article-id><article-id custom-type="elpub" pub-id-type="custom">ymj-349</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>СЛУЧАЙ ИЗ ПРАКТИКИ</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>CLINICAL CASE</subject></subj-group></article-categories><title-group><article-title>Лихорадка денге в Республике Саха (Якутия): случай завозной инфекции</article-title><trans-title-group xml:lang="en"><trans-title>Dengue fever in the Republic of Sakha (Yakutia): a case of imported infection</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-0103-4750</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Слепцова</surname><given-names>С. С.</given-names></name><name name-style="western" xml:lang="en"><surname>Sleptsova</surname><given-names>S. S.</given-names></name></name-alternatives><bio xml:lang="ru"><p>СЛЕПЦОВА Снежана Спиридоновна – д.м.н., доцент, зав. кафедрой</p></bio><bio xml:lang="en"><p>SLEPTSOVA Snezhana Spiridonovna – MD, Associate Professor, Head of the Department of Infectious Diseases, Phthisiology and Dermatovenerоlogy</p></bio><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-2482-2928</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Слепцов</surname><given-names>С. С.</given-names></name><name name-style="western" xml:lang="en"><surname>Sleptsov</surname><given-names>S. S.</given-names></name></name-alternatives><bio xml:lang="ru"><p>СЛЕПЦОВ Спиридон Спиридонович – к.б.н., доцент, с.н.с.</p></bio><bio xml:lang="en"><p>SLEPTSOV Spiridon Spiridonovich – PhD in Biology, Associate Professor, Senior Researcher</p></bio><xref ref-type="aff" rid="aff-2"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Индеева</surname><given-names>Л. Д.</given-names></name><name name-style="western" xml:lang="en"><surname>Indeeva</surname><given-names>L. D.</given-names></name></name-alternatives><bio xml:lang="ru"><p>ИНДЕЕВА Любовь Дмитриевна – к.м.н., врач отделения вирусных гепатитов</p></bio><bio xml:lang="en"><p>INDEEVA Lyubov Dmitrievna – PhD, Doctor of the Viral Hepatitis Department</p></bio><xref ref-type="aff" rid="aff-3"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Антипина</surname><given-names>В. Н.</given-names></name><name name-style="western" xml:lang="en"><surname>Antipina</surname><given-names>V. N.</given-names></name></name-alternatives><bio xml:lang="ru"><p>АНТИПИНА Виктория Николаевна – врач отделения вирусных гепатитов</p></bio><bio xml:lang="en"><p>ANTIPINA Victoria Nikolaevna – doctor of the department of viral hepatitis</p></bio><xref ref-type="aff" rid="aff-4"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Новгородова</surname><given-names>К. О.</given-names></name><name name-style="western" xml:lang="en"><surname>Novgorodova</surname><given-names>K. O.</given-names></name></name-alternatives><bio xml:lang="ru"><p>НОВГОРОДОВА Кристина Олеговна – ординатор</p></bio><bio xml:lang="en"><p>NOVGORODOVA Kristina Olegovna – resident in the specialty ‘Infectious diseases’</p></bio><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Васильева</surname><given-names>М. М.</given-names></name><name name-style="western" xml:lang="en"><surname>Vasilyeva</surname><given-names>M. M.</given-names></name></name-alternatives><bio xml:lang="ru"><p>ВАСИЛЬЕВА Мария Максимовна – зав. отделом, врач-эпидемиолог</p></bio><bio xml:lang="en"><p>VASILIEVA Maria Maksimovna – Head of the Department of Clinical Epidemiology, epidemiologist of the State Budgetary Institution of the Republic of Sakha (Yakutia)</p></bio><xref ref-type="aff" rid="aff-5"/></contrib></contrib-group><aff xml:lang="ru" id="aff-1"><institution>Мединститут СВФУ им. М.К. Аммосова</institution><country>Russian Federation</country></aff><aff-alternatives id="aff-2"><aff xml:lang="ru"><institution>ЯНЦ КМП</institution><country>Россия</country></aff><aff xml:lang="en"><institution>Laboratory of Clinical Population and Medical and Social Research</institution><country>Russian Federation</country></aff></aff-alternatives><aff-alternatives id="aff-3"><aff xml:lang="ru"><institution>Якутская республ. клинич. б-ца</institution><country>Россия</country></aff><aff xml:lang="en"><institution>State Budgetary Institution of the Republic of Sakha (Yakutia) ‘Yakutsk Republican Clinical Hospital’</institution><country>Russian Federation</country></aff></aff-alternatives><aff-alternatives id="aff-4"><aff xml:lang="ru"><institution>Якутская республ. клинич. б-ца</institution><country>Россия</country></aff><aff xml:lang="en"><institution>State Budgetary Institution of the Republic of Sakha (Yakutia) ‘Yakutsk Republican Clinical Hospital</institution><country>Russian Federation</country></aff></aff-alternatives><aff-alternatives id="aff-5"><aff xml:lang="ru"><institution>Якутская республ. клинич. б-ца</institution><country>Россия</country></aff><aff xml:lang="en"><institution>State Budgetary Institution of the Republic of Sakha (Yakutia)</institution><country>Russian Federation</country></aff></aff-alternatives><pub-date pub-type="collection"><year>2023</year></pub-date><pub-date pub-type="epub"><day>10</day><month>02</month><year>2025</year></pub-date><volume>0</volume><issue>3</issue><fpage>126</fpage><lpage>128</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Слепцова С.С., Слепцов С.С., Индеева Л.Д., Антипина В.Н., Новгородова К.О., Васильева М.М., 2025</copyright-statement><copyright-year>2025</copyright-year><copyright-holder xml:lang="ru">Слепцова С.С., Слепцов С.С., Индеева Л.Д., Антипина В.Н., Новгородова К.О., Васильева М.М.</copyright-holder><copyright-holder xml:lang="en">Sleptsova S.S., Sleptsov S.S., Indeeva L.D., Antipina V.N., Novgorodova K.O., Vasilyeva M.M.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://ymj.elpub.ru/jour/article/view/349">https://ymj.elpub.ru/jour/article/view/349</self-uri><abstract><p>На примере клинического наблюдения представлено течение завозной лихорадки денге из Королевства Тайланд. Болезнь протекала с явлениями лимфаденопатии, сыпи, гиперемией зева с явлениями энантемы, практически, с отсутствием интоксикационного синдрома ввиду первичного инфицирования. Необходимо дифференцировать лихорадку денге с другими инфекционными патологиями, протекающими с синдромом экзантемы, энантемой и увеличением лимфоузлов. В диагностическом поиске значимую роль играет также эпидемиологический анамнез. При наличии лихорадки у туристов, вернувшихся из эндемичных стран, необходимо проводить обследование на выявление лихорадки денге.</p></abstract><trans-abstract xml:lang="en"><p>In this article, on the example of clinical observation, the course of imported dengue fever from the Kingdom of Thailand is presented. The disease proceeded with symptoms of lymphadenopathy, rash, hyperemia of the pharynx with symptoms of enanthema and mild intoxication syndrome. It is necessary to diﬀerentiate dengue fever from other infectious pathologies that occur with exanthema syndrome, enanthema, and enlarged lymph nodes. An epidemiological history also plays a signiﬁcant role in the diagnostic search; if tourists who have returned from endemic countries have a fever, it is necessary to conduct an examination for Dengue fever.</p></trans-abstract><kwd-group xml:lang="ru"><kwd>лихорадка денге</kwd><kwd>завозная инфекция</kwd><kwd>лихорадка</kwd><kwd>экзантема</kwd><kwd>лимфаденопатия</kwd></kwd-group><kwd-group xml:lang="en"><kwd>dengue fever</kwd><kwd>imported infection</kwd><kwd>fever</kwd><kwd>exanthema</kwd><kwd>lymphadenopathy</kwd><kwd>Yakutia</kwd></kwd-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Ван Исмаил В.Р., Абдул Маджид М.Ш., Ли Х.Ю. [и др.] Безопасность вакцины от лихорадки денге (CYD-TDV) в Азии: систематический обзор // Инфекция и иммунитет. 2021. 11(3): 447-453. DOI: 10.15789/2220-7619-SOD-1297.</mixed-citation><mixed-citation xml:lang="en">Wan Ismail W.R., Abdul Majid M.Sh., Li H.Y. [et. al.] Safety of dengue vaccine (CYD-TDV) in Asia: a systematic review // Russian Journal of Infection and Immunity = Infektsiya i immunitet, 2021. 11(3): 447-453. DOI: 10.15789/2220-7619-SOD-1297</mixed-citation></citation-alternatives></ref><ref id="cit2"><label>2</label><citation-alternatives><mixed-citation xml:lang="ru">ВОЗ. Информационный бюллетень «Денге и тяжелая денге» [Электронный ресурс]. URL: https://www.who.int/ru/news-room/fact-sheets/detail/dengue-and-severe-dengue</mixed-citation><mixed-citation xml:lang="en">WHO. Newsletter «Dengue and severe dengue» [Electronic resource]. URL: https://www.who.int/ru/news-room/fact-sheets/detail/dengue-and-severe-dengue</mixed-citation></citation-alternatives></ref><ref id="cit3"><label>3</label><citation-alternatives><mixed-citation xml:lang="ru">Государственный доклад «О состоянии санитарно-эпидемиологического благополучия населения в РФ в 2022 г.». М.: Федеральная служба по надзору в сфере защиты прав потребителей и благополучия человека, 2023. 368 с. ISBN 978–5–7508–2012-2.</mixed-citation><mixed-citation xml:lang="en">State report « On the state of sanitary and epidemiological well-being of the population in the Russian Federation in 2022». M.: Federal Service for Surveillance on Consumer Rights Protection and Human Wellbeing, 2023. 368 p. ISBN 978– 5–7508–2012-2.</mixed-citation></citation-alternatives></ref><ref id="cit4"><label>4</label><citation-alternatives><mixed-citation xml:lang="ru">Дьячковская П.С., Слепцова С.С. Впервые выявленный случай заболевания лихорадкой денге в Республике Саха (Якутия) // Медицина. 2019. Т. 7. № 1. С. 55-60. DOI 10.29234/2308-9113-2019-7-1-55-60. – EDN QNCNSP.</mixed-citation><mixed-citation xml:lang="en">Diachkovskaya P.S., Sleptsova S.S. First Identiﬁed Case of Dengue Fever in the Republic of Sakha (Yakutia) // Medicine. 2019. 7(1): 55-60. DOI 10.29234/2308-9113-2019-7-1-55-60. – EDN QNCNSP.</mixed-citation></citation-alternatives></ref><ref id="cit5"><label>5</label><citation-alternatives><mixed-citation xml:lang="ru">Надеев А.П., Мальцева Ю.Г., Шишкина Е.Ю. [и др.] Лихорадка денге с летальным исходом // Архив патологии. 2020. Т. 82, № 1. С. 52-55. DOI 10.17116/patol20208201152. – EDN NDOCJG.</mixed-citation><mixed-citation xml:lang="en">Nadeev A.P., Maltseva Yu. G., Shishkina E.Yu. [et. al] Fatal dengue fever // Archive of Pathology = Arkhiv patologii. 2020; 82(1): 52-55. DOI 10.17116/patol20208201152. – EDN NDOCJG.</mixed-citation></citation-alternatives></ref><ref id="cit6"><label>6</label><citation-alternatives><mixed-citation xml:lang="ru">Российский турпоток в Таиланд по итогам 2022 года вырос в 14 раз [Электронный ресурс]. URL: https://www.atorus.ru/node/51175</mixed-citation><mixed-citation xml:lang="en">The number of Russian tourists traveling to Thailand increased by 14 times in 2022 [Electronic resource]. URL: https://www.atorus.ru/node/51175</mixed-citation></citation-alternatives></ref><ref id="cit7"><label>7</label><citation-alternatives><mixed-citation xml:lang="ru">Dengue plaque reduction neutralization test (PRNT) in primary and secondary dengue virus infections: how alterations in assay conditions impact performance / Thomas S.J., Nisalak A., Anderson K.B., Libraty D.H., Kalayanarooj S., Vaughn D.W., Putnak R., Gibbons R.V., Jarman R., Endy T.P. // Am. J. Trop. Med. Hyg., 2009. Vol. 81, No. 5. P. 825–833. DOI: 10.4269/ajtmh.2009.08-0625</mixed-citation><mixed-citation xml:lang="en">Dengue plaque reduction neutralization test (PRNT) in primary and secondary dengue virus infections: how alterations in assay conditions impact performance / Thomas S.J., Nisalak A., Anderson K.B., Libraty D.H., Kalayanarooj S., Vaughn D.W., Putnak R., Gibbons R.V., Jarman R., Endy T.P. // Am. J. Trop. Med. Hyg., 2009. Vol. 81, No. 5. P. 825–833. DOI: 10.4269/ajtmh.2009.08-0625</mixed-citation></citation-alternatives></ref><ref id="cit8"><label>8</label><citation-alternatives><mixed-citation xml:lang="ru">Safety and immunogenicity of recombinant, live attenuated tetravalent dengue vaccine (CYDTDV) in healthy vietnamese adults and children / Tran N.H., Luong C.Q., Vu T.Q.H., Forrat R., Lang J., Vu Q.D., Bouckenooghe A., Wartel T.A. J. // Vaccines Vaccin., 2012. 3(7): 1000162. DOI: 10.4172/2157-7560.1000162.</mixed-citation><mixed-citation xml:lang="en">Safety and immunogenicity of recombinant, live attenuated tetravalent dengue vaccine (CYDTDV) in healthy vietnamese adults and children / Tran N.H., Luong C.Q., Vu T.Q.H., Forrat R., Lang J., Vu Q.D., Bouckenooghe A., Wartel T.A. J. // Vaccines Vaccin., 2012. 3(7): 1000162. DOI: 10.4172/2157-7560.1000162.</mixed-citation></citation-alternatives></ref><ref id="cit9"><label>9</label><citation-alternatives><mixed-citation xml:lang="ru">Wilder-Smith A, Ooi EE, Horstick O, Wills B. Dengue // Lancet. 2019; 93(10169): 350-363. https://doi.org/10.1016/S0140-6736(18)32560-1</mixed-citation><mixed-citation xml:lang="en">Wilder-Smith A, Ooi EE, Horstick O, Wills B. Dengue // Lancet. 2019; 93(10169): 350-363. https://doi.org/10.1016/S0140-6736(18)32560-1</mixed-citation></citation-alternatives></ref></ref-list><fn-group><fn fn-type="conflict"><p>The authors declare that there are no conflicts of interest present.</p></fn></fn-group></back></article>
