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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">ymj</journal-id><journal-title-group><journal-title xml:lang="ru">Якутский медицинский журнал</journal-title><trans-title-group xml:lang="en"><trans-title>Yakut Medical Journal</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">1813-1905</issn><issn pub-type="epub">2312-1017</issn><publisher><publisher-name>ЯНЦ КМП</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="doi">10.25789/YMJ.2023.83.31</article-id><article-id custom-type="elpub" pub-id-type="custom">ymj-348</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>СЛУЧАЙ ИЗ ПРАКТИКИ</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>CLINICAL CASE</subject></subj-group></article-categories><title-group><article-title>Клинический случай мегалобластной анемии у подростка в сочетании с COVID-19</article-title><trans-title-group xml:lang="en"><trans-title>Clinical case of megaloblastic anemia in a teenager with COVID-19</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Аргунова</surname><given-names>Е. Ф.</given-names></name><name name-style="western" xml:lang="en"><surname>Argunova</surname><given-names>E. F.</given-names></name></name-alternatives><bio xml:lang="ru"><p>АРГУНОВА Елена Филипповна – к.м.н., доцент</p></bio><bio xml:lang="en"><p>ARGUNOVA Elena Filippovna – PhD, Associate Professor</p></bio><email xlink:type="simple">eargunova@mail.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Николаева</surname><given-names>С. А.</given-names></name><name name-style="western" xml:lang="en"><surname>Nikolaeva</surname><given-names>S. A.</given-names></name></name-alternatives><bio xml:lang="ru"><p>НИКОЛАЕВА Саргылана Афанасьевна – детский онколог</p></bio><bio xml:lang="en"><p>NIKOLAEVA Sargylana Afanasievna – pediatric oncologist of the Oncology Department</p></bio><xref ref-type="aff" rid="aff-2"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Кондратьева</surname><given-names>С. А.</given-names></name><name name-style="western" xml:lang="en"><surname>Kondratyeva</surname><given-names>S. A.</given-names></name></name-alternatives><bio xml:lang="ru"><p>КОНДРАТЬЕВА Саргылана Афанасьевна – зав. отделением</p></bio><bio xml:lang="en"><p>KONDRATYEVA Sargylana Afanasyevna – Head of the Oncology Department</p></bio><xref ref-type="aff" rid="aff-2"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Ядреева</surname><given-names>О. В.</given-names></name><name name-style="western" xml:lang="en"><surname>Yadreeva</surname><given-names>O. V.</given-names></name></name-alternatives><bio xml:lang="ru"><p>ЯДРЕЕВА Ольга Валерьевна – врач-гематолог</p></bio><bio xml:lang="en"><p>YADREEVA Olga Valerievna – hematologist of the Oncology Department</p></bio><xref ref-type="aff" rid="aff-2"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Протопопова</surname><given-names>Н. Н.</given-names></name><name name-style="western" xml:lang="en"><surname>Protopopova</surname><given-names>N. N.</given-names></name></name-alternatives><bio xml:lang="ru"><p>ПРОТОПОПОВА Надежда Николаевна – врач-гематолог</p></bio><bio xml:lang="en"><p>PROTOPOPOVA Nadezhda Nikolaevna – hematologist of the Oncology Department</p></bio><xref ref-type="aff" rid="aff-3"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Егорова</surname><given-names>В. Б.</given-names></name><name name-style="western" xml:lang="en"><surname>Egorova</surname><given-names>V. B.</given-names></name></name-alternatives><bio xml:lang="ru"><p>ЕГОРОВА Вера Борисовна – к.м.н., доцент</p></bio><bio xml:lang="en"><p>EGOROVA Vera Borisovna – PhD, Associate Professor of Medical Institute</p></bio><xref ref-type="aff" rid="aff-4"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Лукашевич</surname><given-names>А. С.</given-names></name><name name-style="western" xml:lang="en"><surname>Lukashevich</surname><given-names>A. S.</given-names></name></name-alternatives><bio xml:lang="ru"><p>ЛУКАШЕВИЧ Алина Станиславовна – ординатор</p></bio><bio xml:lang="en"><p>LUKASHEVICH Alina Stanislavovna – second year clinical resident of Medical Institute</p></bio><xref ref-type="aff" rid="aff-4"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru">Мединститут СВФУ им. М.К. Аммосова<country>Россия</country></aff><aff xml:lang="en">Medical Insitute, NEFU<country>Russian Federation</country></aff></aff-alternatives><aff-alternatives id="aff-2"><aff xml:lang="ru">Педиатрический центр РБ № 1-НЦМ МЗ РС(Я)<country>Россия</country></aff><aff xml:lang="en">Pediatric Center of the Republican Hospital №1 of the National Center of Medicine<country>Russian Federation</country></aff></aff-alternatives><aff-alternatives id="aff-3"><aff xml:lang="ru">Педиатрический центр РБ № 1-НЦМ МЗ РС(Я)<country>Россия</country></aff><aff xml:lang="en">Pediatric Center of the Republican Hospital №1 of the national Center of Medicine<country>Russian Federation</country></aff></aff-alternatives><aff-alternatives id="aff-4"><aff xml:lang="ru">Мединститут СВФУ им. М.К. Аммосова<country>Россия</country></aff><aff xml:lang="en">M.K. Ammosov North Eastern Federal University<country>Russian Federation</country></aff></aff-alternatives><pub-date pub-type="collection"><year>2023</year></pub-date><pub-date pub-type="epub"><day>10</day><month>02</month><year>2025</year></pub-date><volume>0</volume><issue>3</issue><fpage>123</fpage><lpage>125</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Аргунова Е.Ф., Николаева С.А., Кондратьева С.А., Ядреева О.В., Протопопова Н.Н., Егорова В.Б., Лукашевич А.С., 2025</copyright-statement><copyright-year>2025</copyright-year><copyright-holder xml:lang="ru">Аргунова Е.Ф., Николаева С.А., Кондратьева С.А., Ядреева О.В., Протопопова Н.Н., Егорова В.Б., Лукашевич А.С.</copyright-holder><copyright-holder xml:lang="en">Argunova E.F., Nikolaeva S.A., Kondratyeva S.A., Yadreeva O.V., Protopopova N.N., Egorova V.B., Lukashevich A.S.</copyright-holder><license license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://ymj.elpub.ru/jour/article/view/348">https://ymj.elpub.ru/jour/article/view/348</self-uri><abstract><p>Представлен клинический случай впервые выявленной мегалобластной анемии в сочетании с интеркуррентным заболеванием COVID-19 у девочки подростка 15 лет из Республики Саха (Якутия). На фоне угнетенного гемопоэза новая коронавирусная инфекция протекала у девочки тяжело, с развитием осложнений в виде внебольничной двусторонней полисегментарной пневмонии и двустороннего экссудативного плеврита, что потребовало наблюдения и лечения в условиях стационара. Проведенная стандартная терапия мегалобластной анемии и пневмонии, вызванной COVID-19, позволила добиться клинико-лабораторного улучшения пациентки и восстановления функции красного костного мозга.</p></abstract><trans-abstract xml:lang="en"><p>This article presents a clinical case of newly diagnosed megaloblastic anemia in a 15-yearold teenager girl from the Republic of Sakha (Yakutia), in combination with intercurrent disease COVID-19. The new coronavirus infection occurs rapidly on the background of of suppressed hematopoiesis, with the development of complications in the form of community-acquired bilateral severe polysegmental pneumonia and bilateral exudative pleurisy, which required observation and treatment in a hospital. The performed standard complex therapy for megaloblastic anemia and pneumonia caused by SARS-CoV-2 made it possible to achieve clinical and laboratory improvement in the patient and restore the function of the red bone marrow.</p></trans-abstract><kwd-group xml:lang="ru"><kwd>мегалобластная анемия</kwd><kwd>В-12 дефицитная анемия</kwd><kwd>фолиево-дефицитная анемия</kwd><kwd>COVID-19</kwd><kwd>пневмония</kwd></kwd-group><kwd-group xml:lang="en"><kwd>megaloblastic anemia</kwd><kwd>cobalamin deficiency</kwd><kwd>folic acid deficiency</kwd><kwd>COVID-19</kwd><kwd>new coronavirus infection</kwd><kwd>pneumonia</kwd></kwd-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Комиссаренко И.А. Внутренние болезни на догоспитальном этапе. Анемический синдром: Мат-лы науч.-практич. конф. студентов, ординаторов и молодых ученых. М.: ФГАОУ ВО РНИМУ им. Н.И. Пирогова Минздрава России, 2020. 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