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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">ymj</journal-id><journal-title-group><journal-title xml:lang="ru">Якутский медицинский журнал</journal-title><trans-title-group xml:lang="en"><trans-title>Yakut Medical Journal</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">1813-1905</issn><issn pub-type="epub">2312-1017</issn><publisher><publisher-name>ЯНЦ КМП</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="doi">10.25789/YMJ.2026.94.19</article-id><article-id custom-type="elpub" pub-id-type="custom">ymj-3323</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>АРКТИЧЕСКАЯ МЕДИЦИНА</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>ARCTIC MEDICINE</subject></subj-group></article-categories><title-group><article-title>Йододефицит у детей Арктики: связь с физическим развитием и функцией щитовидной железы</article-title><trans-title-group xml:lang="en"><trans-title>Iodine deficiency in Arctic children: association with physical development and thyroid function</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0001-8022-3279</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Чебаргина</surname><given-names>М. А.</given-names></name><name name-style="western" xml:lang="en"><surname>Chebargina</surname><given-names>M. A.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Чебаргина Мария Александровна – канд. мед. наук, доц. кафедры педиатрии, неонатологии и перинатологии с курсом неотложной медицины.</p><p>ул. Муравьева – Амурского, д. 35, Хабаровск, 680000</p></bio><email xlink:type="simple">marie_work95@mail.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0003-4195-2350</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Сенькевич</surname><given-names>О. А.</given-names></name><name name-style="western" xml:lang="en"><surname>Senkevich</surname><given-names>O. A.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Сенькевич Ольга Александровна – д-р мед. наук, проф., зав. кафедрой педиатрии, неонатологии и перинатологии с курсом неотложной медицины.</p><p>ул. Муравьева – Амурского, д. 35, Хабаровск, 680000</p></bio><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0003-1803-9168</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Ковальский</surname><given-names>Ю. Г.</given-names></name><name name-style="western" xml:lang="en"><surname>Kovalsky</surname><given-names>Yu. G.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Ковальский Юрий Григорьевич – д-р мед. наук, проф., зав. кафедрой биологической химии и клинической лабораторной диагностики.</p><p>ул. Муравьева – Амурского, д. 35, Хабаровск, 680000</p></bio><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0009-0007-3378-7961</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Пикалова</surname><given-names>В. М.</given-names></name><name name-style="western" xml:lang="en"><surname>Pikalova</surname><given-names>V. M.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Пикалова Вероника Михайловна – канд. мед. наук, доц. кафедры биологической химии и клинической лабораторной диагностики.</p><p>ул. Муравьева – Амурского, д. 35, Хабаровск, 680000</p></bio><xref ref-type="aff" rid="aff-1"/></contrib></contrib-group><aff xml:lang="ru" id="aff-1"><institution>ФГБОУ ВО «Дальневосточный государственный медицинский университет» Министерства здравоохранения Российской Федерации</institution><country>Russian Federation</country></aff><pub-date pub-type="collection"><year>2026</year></pub-date><pub-date pub-type="epub"><day>21</day><month>06</month><year>2026</year></pub-date><volume>0</volume><issue>2</issue><fpage>81</fpage><lpage>86</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Чебаргина М.А., Сенькевич О.А., Ковальский Ю.Г., Пикалова В.М., 2026</copyright-statement><copyright-year>2026</copyright-year><copyright-holder xml:lang="ru">Чебаргина М.А., Сенькевич О.А., Ковальский Ю.Г., Пикалова В.М.</copyright-holder><copyright-holder xml:lang="en">Chebargina M.A., Senkevich O.A., Kovalsky Y.G., Pikalova V.M.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://ymj.elpub.ru/jour/article/view/3323">https://ymj.elpub.ru/jour/article/view/3323</self-uri><abstract><p>Проведено обсервационное, аналитическое, поперечное исследование оценки взаимосвязи йодного статуса с показателями гормонального профиля щитовидной железы и отклонениями физического развития у детей-жителей Арктической зоны Дальневосточного федерального округа (Чукотский автономный округ, г. Анадырь). Состояние йододефицита у детей в возрасте от 1 до 18 лет (n=120) наблюдалось в 80,9% случаев, при этом наиболее часто встречался дефицит средней степени тяжести (37,5% детей). Установлена тенденция к опережающему физическому развитию с высокой распространенностью избыточной массы тела и ожирения – 16,2% и 16,8% случаев соответственно. При проведении корреляционного анализа было обнаружено нарастание значений индекса массы тела (ИМТ) у детей школьного возраста при усугублении йододефицита (r = -0,312, p = 0,015). Анализ тиреоидного статуса показал, что 13,5% детей имели признаки субклинического гипотиреоза, распространенность которого не имела статистически значимых различий при сравнении различных возрастных групп (p = 0,270). В результате проведенного ROC-анализа было определено, что содержание йода в организме детей равное 42,5 мкг/мл и менее повышает риск увеличения тиреотропного гормона выше 4,0 мкМЕ/мл.</p></abstract><trans-abstract xml:lang="en"><p>An observational, analytical, cross-sectional study was conducted to assess the relationship between iodine status, thyroid hormonal profile parameters, and physical developmental deviations in children living in the Arctic zone of the Far Eastern Federal District (Chukotka Autonomous Okrug, Anadyr). Iodine deficiency in children aged 1 to 18 years (n=120) was observed in 80.9% of cases, with moderate deficiency being the most common (37.5% of children). A trend toward accelerated physical development was identified, with a high prevalence of overweight and obesity – 16.2% and 16.8% of cases, respectively. A correlation analysis revealed an increase in BMI values in school-age children with increasing iodine deficiency (r = -0.312, p = 0.015). An analysis of thyroid status revealed that 13.5% of children had signs of subclinical hypothyroidism, the prevalence of which did not differ statistically significantly when comparing different age groups (p = 0.270). A ROC-analysis revealed that iodine levels in children of 42.5 μg/ml or less increase the risk of thyroid-stimulating hormone levels exceeding 4.0 μIU/ml.</p></trans-abstract><kwd-group xml:lang="ru"><kwd>йод</kwd><kwd>йодурия</kwd><kwd>йододефицит</kwd><kwd>дети</kwd><kwd>Арктическая зона</kwd><kwd>физическое развитие</kwd><kwd>тиреоидный профиль</kwd><kwd>Z-scores</kwd></kwd-group><kwd-group xml:lang="en"><kwd>iodine</kwd><kwd>urinary iodine concentration</kwd><kwd>iodine deficiency</kwd><kwd>children</kwd><kwd>Arctic zone</kwd><kwd>physical development</kwd><kwd>thyroid profile</kwd><kwd>Z-scores</kwd></kwd-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Liang D. 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