ymjЯкутский медицинский журналYakut Medical Journal1813-19052312-1017ЯНЦ КМП10.25789/YMJ.2023.83.23ymj-304Research ArticleАРКТИЧЕСКАЯ МЕДИЦИНАARCTIC MEDICINEВзаимосвязь показателей гипофизарно-гонадной оси и дофамина с метеорологическими факторами у здоровых мужчин, проживающих в СубарктикеThe relationship of parameters of the pituitary-gonadal axis and dopamine with meteorological factors in healthy men living in the Subarctichttps://orcid.org/0000-0003-3097-9427МолодовскаяИ. Н.MolodovskayaI. N.

МОЛОДОВСКАЯ Ирина Николаевна – к.б.н., с.н.с.

MOLODOVSKAYA Irina Nikolaevna – PhD in Biology, senior researcher

pushistiy-86@mail.ruhttps://orcid.org/0000-0003-2097-3806ТиписоваЕ. В.TipisovaE. V.

ТИПИСОВА Елена Васильевна – д.б.н., гл.н.с.

TIPISOVA Elena Vasilievna – Doctor of Biology, chief researcher

https://orcid.org/0000-0003-2519-1600ЕлфимоваА. Э.ElfimovaA. E.

ЕЛФИМОВА Александра Эдуардовна – к.б.н., с.н.с.

ELFIMOVA Alexandra Eduardovna – PhD in Biology, senior researcher

https://orcid.org/0000-0002-0818-7274АликинаВ. А.AlikinaV. A.

АЛИКИНА Виктория Анатольевна – к.б.н., с.н.с.

ALIKINA Victoria Anatolievna – PhD in Biology, senior researcher

https://orcid.org/0000-0001-6133-8249ЗябишеваВ. Н.ZyabishevaV. N.

ЗЯБИШЕВА Валентина Николаевна – м.н.с.

ZYABISHEVA Valentina Nikolaevna – junior researcher

ФИЦ комплексного изучения Арктики им. академика Н.П. Лаверова Уральского отделения РАНРоссияN. Laverov Federal Center for Integrated Arctic ResearchRussian Federation202307022025039397Copyright © Молодовская И.Н., Типисова Е.В., Елфимова А.Э., Аликина В.А., Зябишева В.Н., 20252025Молодовская И.Н., Типисова Е.В., Елфимова А.Э., Аликина В.А., Зябишева В.Н.Molodovskaya I.N., Tipisova E.V., Elfimova A.E., Alikina V.A., Zyabisheva V.N.Данная работа распространяется под лицензией Creative Commons Attribution 4.0.This work is licensed under a Creative Commons Attribution 4.0 License.https://ymj.elpub.ru/jour/article/view/304

Сезонные колебания уровней эстрадиола и антиспермальных антител сопоставимы с изменениями продолжительности светового дня, колебаниями атмосферного давления, температуры и относительной влажности воздуха. Сезонные изменения уровня ЛГ связаны с колебаниями атмосферного давления воздуха. Экстремальные значения дневного света оказывают влияние на годовую динамику дофамина, который также коррелировал с атмосферным давлением и относительной влажностью воздуха. Уровни общего и свободного тестостерона у мужчин относительно постоянны в течение года и, по-видимому, не зависят от факторов погоды.

Aim

Aim: to evaluate the influence of circannual dynamics of meteorological factors of the temperate continental climate on the levels of sex hormones and dopamine as well as antisperm antibodies in men living in subarctic environmental conditions.

Materials and methods

Materials and methods. The concentrations of follicle stimulating hormone, luteinizing hormone, prolactin, progesterone, dopamine, cortisol, total and free testosterone, estradiol, sex hormone-binding globulin, dehydroepiandrosterone sulphate, antisperm antibodies were determined in the blood by the enzyme immunoassay on a quarterly basis (December, March, June, September) for one year in 20 healthy men of Arkhangelsk. The relationships between the hormonal data and the climatic data were assessed by using the Spearman correlation coefficient.

Results

Results. Seasonal fluctuations in the levels of estradiol and antisperm antibodies are comparable to changes in the daylight hours, fluctuations in atmospheric pressure, temperature and relative humidity. Seasonal changes in luteinizing hormone levels are associated with the fluctuations in atmospheric air pressure. Daylight affect annual dopamine dynamics, which also correlated with atmospheric pressure and relative air humidity. Total and free testosterone levels in men are relatively constant throughout the year and do not appear to be influenced by the weather factors.

Conclusion

Conclusion. An increase in day length and air temperature is associated with an increase in estradiol and dopamine levels and a decrease in antisperm antibodies values. We believe that the seasonality of estradiol and antisperm antibodies is a daylight effect mediated by changes in the melatonin levels, just as dopamine seasonality is mediated by changes in vitamin D levels.

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The authors declare that there are no conflicts of interest present.