ymjЯкутский медицинский журналYakut Medical Journal1813-19052312-1017ЯНЦ КМП10.25789/YMJ.2025.92.24ymj-3038Research ArticleНАУЧНЫЕ ОБЗОРЫSCIENTIFIC REVIEWSПодходы к лечению аутосомно-доминантных спиноцеребеллярных атаксийApproaches to the treatment of autosomal-dominant spinocerebellar ataxiashttps://orcid.org/0000-0002-2143-0021КононоваС. К.KononovaS. K.

Кононова Сардана Кононовна – к.б.н., гл.н.с.-руковод. отдела ЯНЦ КМП.

677000, Якутск, ул. Ярославского, 6/3

konsard@rambler.ruЯНЦ КМПRussian Federation20253012202504113117Copyright © Кононова С.К., 20252025Кононова С.К.Kononova S.K.Данная работа распространяется под лицензией Creative Commons Attribution 4.0.This work is licensed under a Creative Commons Attribution 4.0 License.https://ymj.elpub.ru/jour/article/view/3038

Статья посвящена вопросам перспектив лечения нейродегенеративных болезней с динамическими мутациями по данным опубликованных исследований поиска подходов к терапии спиноцеребеллярных атаксий. Хотя эти заболевания неизлечимы, результаты исследований показывают, что некоторые лекарства и физиотерапия могут облегчить симптомы мозжечковой атаксии. Благодаря прогрессу в изучении спиноцеребеллярных атаксий, достигнутому в последние годы, есть большие надежды на то, что можно будет разработать методы генной терапии, которые замедлят прогрессирование заболевания или даже остановят его развитие.

The article is devoted to the prospects for the treatment of neurodegenerative diseases with dynamic mutations based on published studies of the search for approaches to the treatment of spinocerebellar ataxia. Although these diseases are incurable, research results show that certain medications and physical therapy can alleviate the symptoms of cerebellar ataxia. Due to the progress made in the study of spinocerebellar ataxia in recent years, there are high hopes that it will be possible to develop gene therapy methods that will slow down the progression of the disease or even stop its development.

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The authors declare that there are no conflicts of interest present.