ymjЯкутский медицинский журналYakut Medical Journal1813-19052312-1017ЯНЦ КМП10.1234/YMJ.2022.77.24ymj-30Research ArticleАРКТИЧЕСКАЯ МЕДИЦИНАARCTIC MEDICINEОпределение концентрации 25(ОН) витамина D у лиц трудоспособного населения Северного регионаDetermination of vitamin D concentration of 25(OH) in the working-age population of the Northern Regionhttps://orcid.org/0000-0002-4511-6782АверьяноваИ. В.AveryanovaI. V.

Аверьянова Инесса Владиславовна – к.б.н., в.н.с.

Магадан

Inessa V. Averyanova – Biology Doctor, Head Researcher, Laboratory for Physiology of Extreme States, Arktika Scientific Research Center, Far Eastern Branch of the Russian Academy of Sciences.

Inessa1382@mail.ruhttps://orcid.org/0000-0002-6583-4175ЛуговаяЕ. А.LugovayaE. A.

Луговая Елена Александровна – к.б.н., доцент, директор.

Магадан

Elena A. Lugovaya – Candidate of Biological Sciences, Associate Professor, Acting Director of the Federal State Budgetary Institution of Science, Arktika Scientific Research Center, Far Eastern Branch of the Russian Academy of Sciences.

elena_plant@mail.ruФГБУН НИЦ «Арктика» ДВО РАНРоссияArktika Scientific Research Center, Far Eastern Branch of the Russian Academy of SciencesRussian Federation202202022025019399Copyright © Аверьянова И.В., Луговая Е.А., 20252025Аверьянова И.В., Луговая Е.А.Averyanova I.V., Lugovaya E.A.Данная работа распространяется под лицензией Creative Commons Attribution 4.0.This work is licensed under a Creative Commons Attribution 4.0 License.https://ymj.elpub.ru/jour/article/view/30

Проведено определение концентрации 25(ОН) витамина D с дальнейшим сравнительным анализом основных показателей физического развития, сердечно-сосудистой системы, биохимического и микроэлементного профиля организма у лиц с недостаточностью и оптимальной концентрацией витамина D трудоспособного возраста, проживающих в Северном регионе.

Установлено, что для лиц с недостаточностью по уровню витамина D характерны нарушения со стороны показателей физического развития, сердечно-сосудистой системы, характеристик биохимического и микроэлементного профиля. В целом полученные результаты нашего исследования могут являться базой для формирования рекомендаций, направленных на коррекцию проявлений дефицита/недостаточности уровня витамина D у жителей Северо-Востока России.

The study examined working-age population of the North region to determine 25 (OH) vitamin D concentrations and compared insufficient subjects (Group 1) with those having the proper/optimal vitamin D concentration (Group 2) in terms of main indicators of physical development, cardiovascular system, biochemical and trace element picture.

Material and Methods

Material and Methods: fifty-five men of working age (mean age was 37.4±0.5 yr.) all Caucasians residing in the territory of Magadan region participated in the research. We used photometric, immunochemiluminescent and spectrometric methods of investigation, as well as standard cardiovascular and anthropometric measurements. Study Results: 42% (Group 1) tested low for vitamin D while 58% (Group 2) had the proper vitamin amounts. Group 1 was up to 78% made up of high body mass index men versus 40% of subjects exceeding standard range of this index in Group 2. Cardiovascular system and circulation values tended to be increasingly stressed and high thyroid-stimulating hormone indicated the development of preclinical hypothyroid pathology with Group 1 examinees. They were more atherogenic in lipid pictures in comparison with Group 2 northerners who showed a shift towards healthier lipid profiles. Moreover, vitamin D deficient subjects proved to also lack vitamin B12 and were low in trace elements.

Conclusion

Conclusion: Subjective vitamin D deficits develop disorders in physical development, cardiovascular system, as well as biochemical and trace element profiles. Our study can be applied for making recommendations on correcting vitamin D deficiency/insufficiency in residents of Russia’s northeast.

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The authors declare that there are no conflicts of interest present.