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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">ymj</journal-id><journal-title-group><journal-title xml:lang="ru">Якутский медицинский журнал</journal-title><trans-title-group xml:lang="en"><trans-title>Yakut Medical Journal</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">1813-1905</issn><issn pub-type="epub">2312-1017</issn><publisher><publisher-name>ЯНЦ КМП</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="doi">10.25789/YMJ.2020.71.25</article-id><article-id custom-type="elpub" pub-id-type="custom">ymj-2997</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>НАУЧНЫЕ ОБЗОРЫ И ЛЕКЦИИ</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>SCIENTIFIC REVIEWS AND LECTURES</subject></subj-group></article-categories><title-group><article-title>Перспективные природные соединения как возможные средства профилактики и лечения новой коронавирусной инфекции, вызванной вирусом SARS-CoV-2</article-title><trans-title-group xml:lang="en"><trans-title>Promising natural compounds as possible means of prevention and treatment of the novel coronavirus infection caused by the SARS-CoV-2 virus</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Николаев</surname><given-names>В. М.</given-names></name><name name-style="western" xml:lang="en"><surname>Nikolaev</surname><given-names>V. M.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Николаев Вячеслав Михайлович – к.б.н., гл.н.с.–руковод. отдела</p></bio><email xlink:type="simple">Nikolaev1126@mail.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Чирикова</surname><given-names>Н. К.</given-names></name><name name-style="western" xml:lang="en"><surname>Chirikova</surname><given-names>N. K.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Чирикова Надежда Константиновна – д.фарм.н., проф.</p></bio><email xlink:type="simple">hofnung@mail.ru</email><xref ref-type="aff" rid="aff-2"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Софронова</surname><given-names>С. И.</given-names></name><name name-style="western" xml:lang="en"><surname>Sofronova</surname><given-names>S. I.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Софронова Саргылана Ивановна – к.м.н., гл.н.с.– руковод. отдела</p></bio><email xlink:type="simple">sara2208@mail.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Румянцев</surname><given-names>Е. К.</given-names></name><name name-style="western" xml:lang="en"><surname>Rumyancev</surname><given-names>E. K.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Румянцев Егор Константинович – м.н.с.</p></bio><email xlink:type="simple">tzeentch1993@mail.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Васильева</surname><given-names>А. Г.</given-names></name><name name-style="western" xml:lang="en"><surname>Vasileva</surname><given-names>A. G.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Васильева Айна Григорьевна – студент ИЕН </p></bio><email xlink:type="simple">kagamisatou@gmail.com</email><xref ref-type="aff" rid="aff-3"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Романова</surname><given-names>А. Н.</given-names></name><name name-style="western" xml:lang="en"><surname>Romanova</surname><given-names>A. N.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Романова Анна Николаевна – д.м.н, директор</p></bio><email xlink:type="simple">ranik@mail.ru</email><xref ref-type="aff" rid="aff-1"/></contrib></contrib-group><aff xml:lang="ru" id="aff-1"><institution>ЯНЦ КМП</institution><country>Russian Federation</country></aff><aff xml:lang="ru" id="aff-2"><institution>Ин-та естественных наук СВФУ им. М.К. Аммосова</institution><country>Russian Federation</country></aff><aff xml:lang="ru" id="aff-3"><institution>СВФУ им. М.К. Аммосова</institution><country>Russian Federation</country></aff><pub-date pub-type="collection"><year>2020</year></pub-date><pub-date pub-type="epub"><day>11</day><month>12</month><year>2025</year></pub-date><volume>0</volume><issue>3</issue><fpage>95</fpage><lpage>101</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Николаев В.М., Чирикова Н.К., Софронова С.И., Румянцев Е.К., Васильева А.Г., Романова А.Н., 2025</copyright-statement><copyright-year>2025</copyright-year><copyright-holder xml:lang="ru">Николаев В.М., Чирикова Н.К., Софронова С.И., Румянцев Е.К., Васильева А.Г., Романова А.Н.</copyright-holder><copyright-holder xml:lang="en">Nikolaev V.M., Chirikova N.K., Sofronova S.I., Rumyancev E.K., Vasileva A.G., Romanova A.N.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://ymj.elpub.ru/jour/article/view/2997">https://ymj.elpub.ru/jour/article/view/2997</self-uri><abstract><p>В обзоре литературы представлен накопленный научный опыт многих исследователей, занимавшихся поиском метаболитов растительного происхождения, обладающих потенциальным действием против SARS-CoV-2. В отличие от синтетических лекарственных веществ, растительные противовирусные препараты не требуют трудоемкого фармацевтического синтеза и являются более доступными и относительно безопасными. В данной работе проведен поиск перспективных природных соединений как возможных средств профилактики и лечения новой коронавирусной инфекции, вызванной вирусом SARS-CoV-2.</p></abstract><trans-abstract xml:lang="en"><p>The literature review presents the accumulated scientific experience of many researchers searching for plant-derived metabolites with potential action against SARS-CoV-2. Unlike synthetic drugs, herbal antiviral drugs do not require labor-intensive pharmaceutical synthesis and are more affordable and relatively safe. In this work, we searched for promising natural compounds as possible means of preventing and treating a new coronavirus infection caused by the SARS-CoV-2 virus.</p></trans-abstract><kwd-group xml:lang="ru"><kwd>SARS-CoV-2</kwd><kwd>фенольные соединения</kwd><kwd>терпеноиды</kwd><kwd>алкалоиды</kwd><kwd>лектины</kwd><kwd>жизненный цикл вируса</kwd><kwd>таксономия вируса</kwd><kwd>ангиотензинпревращающий фермент 2</kwd><kwd>РНК-зависимая РНК-полимераза</kwd><kwd>3C-подобная протеаза</kwd><kwd>папаиноподобная протеаза</kwd><kwd>геликаза</kwd></kwd-group><kwd-group xml:lang="en"><kwd>SARS-CoV-2</kwd><kwd>phenolic compounds</kwd><kwd>terpenoids</kwd><kwd>alkaloids</kwd><kwd>lectins</kwd><kwd>virus life cycle</kwd><kwd>virus taxonomy</kwd><kwd>angiotensin-converting enzyme 2</kwd><kwd>RNA-dependent RNA polymerase</kwd><kwd>3C-like protease</kwd><kwd>papain-like protease</kwd><kwd>helicase</kwd></kwd-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Кузнецова Л.В. 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