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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">ymj</journal-id><journal-title-group><journal-title xml:lang="ru">Якутский медицинский журнал</journal-title><trans-title-group xml:lang="en"><trans-title>Yakut Medical Journal</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">1813-1905</issn><issn pub-type="epub">2312-1017</issn><publisher><publisher-name>ЯНЦ КМП</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="doi">10.25789/YMJ.2020.71.21</article-id><article-id custom-type="elpub" pub-id-type="custom">ymj-2993</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>АРКТИЧЕСКАЯ МЕДИЦИНА</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>ARCTIC MEDICINE</subject></subj-group></article-categories><title-group><article-title>Вклад некоторых биохимических и иммунологических показателей в развитие артериальной гипертензии и ожирения у жителей Арктики</article-title><trans-title-group xml:lang="en"><trans-title>Contribution of certain biochemical and immunological indicators to the development of arterial hypertension and obesity in Arctic residents</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0003-0010-9850</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Софронова</surname><given-names>С. И.</given-names></name><name name-style="western" xml:lang="en"><surname>Sofronova</surname><given-names>S. I.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Софронова Саргылана Ивановна – к.м.н., гл.н.с.-руковод. отдела</p></bio><email xlink:type="simple">sara2208@mail.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Николаев</surname><given-names>В. М.</given-names></name><name name-style="western" xml:lang="en"><surname>Nikolaev</surname><given-names>V. M.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Николаев Вячеслав Михайлович – к.б.н., гл.н.с. – руковод. отдела</p></bio><email xlink:type="simple">Nikolaev1126@mail.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Кириллина</surname><given-names>М. П.</given-names></name><name name-style="western" xml:lang="en"><surname>Kirillina</surname><given-names>M. P.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Кириллина Мария Петровна – к.б.н., в.н.с. – руковод. лаб.</p></bio><email xlink:type="simple">kirillinamp@mail.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-4817-5315</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Романова</surname><given-names>А. Н.</given-names></name><name name-style="western" xml:lang="en"><surname>Romanova</surname><given-names>A. N.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Романова Анна Николаевна – д.м.н., директор</p></bio><email xlink:type="simple">ranik@mail.ru</email><xref ref-type="aff" rid="aff-1"/></contrib></contrib-group><aff xml:lang="ru" id="aff-1"><institution>ЯНЦ КМП</institution><country>Russian Federation</country></aff><pub-date pub-type="collection"><year>2020</year></pub-date><pub-date pub-type="epub"><day>11</day><month>12</month><year>2025</year></pub-date><volume>0</volume><issue>3</issue><fpage>80</fpage><lpage>83</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Софронова С.И., Николаев В.М., Кириллина М.П., Романова А.Н., 2025</copyright-statement><copyright-year>2025</copyright-year><copyright-holder xml:lang="ru">Софронова С.И., Николаев В.М., Кириллина М.П., Романова А.Н.</copyright-holder><copyright-holder xml:lang="en">Sofronova S.I., Nikolaev V.M., Kirillina M.P., Romanova A.N.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://ymj.elpub.ru/jour/article/view/2993">https://ymj.elpub.ru/jour/article/view/2993</self-uri><abstract><p>Проведено исследование у коренных малочисленных народов Севера на арктической территории Якутии ассоциации некоторых биохимических и иммунологических показателей с абдоминальным ожирением и артериальной гипертензией. Полученные данные показывают, что у гипертоников отмечается высокая частота абдоминального ожирения, повышенного содержания холестерина за счет атерогенной фракции. Получена статистически значимая взаимосвязь уровней глюкозы и липидов крови с объемом талии и систолическим артериальным давлением. Из провоспалительных цитокинов получена значимая корреляция ИЛ-6 с абдоминальным ожирением у гипертоников. </p></abstract><trans-abstract xml:lang="en"><p>A study of the association of certain biochemical and immunological parameters with abdominal obesity and arterial hypertension was carried in indigenous peoples of the North of the Arctic territory of Yakutia. The data show that hypertensive patients have a high frequency of abdominal obesity, high cholesterol due to the atherogenic fraction. A statistically significant reliable relationship was revealed between the levels of glucose and lipids with waist size and systolic blood pressure. Significant correlation of pro-inflammatory cytokine IL-6 with abdominal obesity in hypertensive patients was obtained.</p></trans-abstract><kwd-group xml:lang="ru"><kwd>липиды</kwd><kwd>С-пептид</kwd><kwd>инсулин</kwd><kwd>провоспалительные цитокины</kwd><kwd>артериальная гипертензия</kwd><kwd>абдоминальное ожирение</kwd><kwd>коренные малочисленные народы Севера</kwd></kwd-group><kwd-group xml:lang="en"><kwd>lipids</kwd><kwd>C-peptide</kwd><kwd>insulin</kwd><kwd>pro-inflammatory cytokines</kwd><kwd>arterial hypertension</kwd><kwd>abdominal obesity</kwd><kwd>indigenous peoples of the North</kwd></kwd-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Карагодин В.П. Воспаление, иммунокомпетентные клетки, цитокины - роль в атерогенезе / В.П. Карагодин, Ю.В. Бобрышев, А.Н. Орехов // Патогенез. - 2014. - №1(12). - С.21-35.</mixed-citation><mixed-citation xml:lang="en">V.P. 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