ymjЯкутский медицинский журналYakut Medical Journal1813-19052312-1017ЯНЦ КМПymj-2495Research ArticleОРИГИНАЛЬНЫЕ ИССЛЕДОВАНИЯORIGINAL RESEARCHАссоциация полиморфизма гена В2-адренорецептора с атопической бронхиальной астмой в якутской популяцииAssociation of gene В2-adrenoreceptor polymorphism with atopic bronchial asthma in the Yakut populationСоловьеваН. А.SolovevaN. A.

Соловьева Наталья Алексеевна – м.н.с.

sonata608@yandex.ruНиколаеваЛ. Е.NikolaevaL. E.

Николаева Лена Егоровна - зав. отделением

МаксимоваН. Р.MaksimovaN. R.

Максимова Надежда Романовна – к.м.н., гл.н.с.

ЯНЦ КМП СО РАМНRussian FederationРБ №1 НЦМ РС(Я)Russian Federation200928102025034142Copyright © Соловьева Н.А., Николаева Л.Е., Максимова Н.Р., 20252025Соловьева Н.А., Николаева Л.Е., Максимова Н.Р.Soloveva N.A., Nikolaeva L.E., Maksimova N.R.Данная работа распространяется под лицензией Creative Commons Attribution 4.0.This work is licensed under a Creative Commons Attribution 4.0 License.https://ymj.elpub.ru/jour/article/view/2495

Представлены результаты анализа ассоциации полиморфного варианта A46G гена В2-адренорецептора (ADRB2) c атопической бронхиальной астмой (БА). Исследование проведено в группе из 86 неродственных больных атопической БА, якутов по этнической принадлежности, и 195 здоровых неродственных якутов. Ассоциация замены 46А>G гена ADRB2 с атопической БА в якутской популяции не установлена.

Results of the analysis of polymorphic variant A46G association of gene В2-adrenoreceptor (ADRB2) with atopic bronchial asthma (BА) are presented. Research is lead in group of 86 unrelated patients with atopic BA, Yakuts by ethnicity, and 195 healthy unrelated Yakuts. The association of replacement 46А> G gene ADRB2 with atopic BA in the Yakut population is not established.

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The authors declare that there are no conflicts of interest present.