ymjЯкутский медицинский журналYakut Medical Journal1813-19052312-1017ЯНЦ КМП10.25789/YMJ.2023.82.25ymj-246Research ArticleНАУЧНЫЕ ОБЗОРЫ И ЛЕКЦИИSCIENTIFIC REVIEWS AND LECTURESНейровоспаление и функционирование головного мозга: возможные последствия у детей, инфицированных COVID-19Neuroinflammation and brain functioning: possible implications in children infected with COVID-19ГуляевА. А.GulyaevA. A.

Артем Александрович Гуляев, студент 6 курса

Благовещенск

Blagoveshchensk

Superstar533129@gmail.comДробяскинаК. А.DrobyaskinaK. A.

Ксения Анатольевна Дробяскина, студентка 3 курса

Благовещенск

Blagoveshchensk

СинякинИ. А.SinyakinI. A.

Иван Алексеевич Синякин, студент 5 курса; лаб.-исслед.

Благовещенск

Blagoveshchensk

БаталоваТ. А.BatalovaT. A.

Татьяна Анатольевна Баталова, д. б. н., проф., зав. кафедрой

Благовещенск

Blagoveshchensk

ФГБОУ ВО Амурская ГМА Минздрава РоссииРоссияAmur State Medical Academy of the Ministry of Health of the Russian FederationRussian FederationФГБОУ ВО Амурская ГМА Минздрава России; Дальневосточный НЦ физиологии и патологии дыханияРоссияAmur State Medical Academy of the Ministry of Health of the Russian Federation; Far Eastern Research Center of Physiology and Pathology of RespirationRussian Federation20230602202502106111Copyright © Гуляев А.А., Дробяскина К.А., Синякин И.А., Баталова Т.А., 20252025Гуляев А.А., Дробяскина К.А., Синякин И.А., Баталова Т.А.Gulyaev A.A., Drobyaskina K.A., Sinyakin I.A., Batalova T.A.Данная работа распространяется под лицензией Creative Commons Attribution 4.0.This work is licensed under a Creative Commons Attribution 4.0 License.https://ymj.elpub.ru/jour/article/view/246

   В статье рассмотрены научные данные, основанные на современной литературе о нейровоспалении и функционировании головного мозга у детей, инфицированных COVID-19. Многочисленные исследования показали, что как и при других вирусных инфекциях, таких как краснуха, грипп и цитомегаловирус, SARS-CoV-2 вызывает массивное высвобождение провоспалительных цитокинов, которые влияют на функцию микроглии, что может быть критичным для развития мозга. Кроме того, в исследованиях сообщалось о транзиторном тиреотоксикозе, вызванном SARS-CoV-2, с вторичным аутоиммунным гипотиреозом, который может остаться незамеченным во время беременности.

   This article reviews scientific data based on the current literature on neuroinflammation and brain function in children infected with COVID-19. Numerous studies have shown that, as in other viral infections such as rubella, influenza, and cytomegalovirus, SARS-CoV-2 causes massive release of proinflammatory cytokines that affect microglia function, which may be critical for brain development. In addition, studies have reported transient thyrotoxicosis caused by SARS-CoV-2 with secondary autoimmune hypothyroidism that may go undetected during pregnancy.

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The authors declare that there are no conflicts of interest present.