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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">ymj</journal-id><journal-title-group><journal-title xml:lang="ru">Якутский медицинский журнал</journal-title><trans-title-group xml:lang="en"><trans-title>Yakut Medical Journal</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">1813-1905</issn><issn pub-type="epub">2312-1017</issn><publisher><publisher-name>ЯНЦ КМП</publisher-name></publisher></journal-meta><article-meta><article-id custom-type="elpub" pub-id-type="custom">ymj-2286</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>ОРИГИНАЛЬНЫЕ ИССЛЕДОВАНИЯ</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>ORIGINAL RESEARCH</subject></subj-group></article-categories><title-group><article-title>Оценка активности воспалительного процесса при внебольничной пневмонии</article-title><trans-title-group xml:lang="en"><trans-title>Estimation of inflammatory process activity at extra-hospital pneumonia</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Федосова</surname><given-names>Е. Ю.</given-names></name><name name-style="western" xml:lang="en"><surname>Fedosova</surname><given-names>E. J.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Федосова Екатерина Юрьевна – аспирант</p></bio><email xlink:type="simple">matas7@inbox.ru</email><xref ref-type="aff" rid="aff-1"/></contrib></contrib-group><aff xml:lang="ru" id="aff-1"><institution>Дальневосточный научный центр физиологии и патологии дыхания СО РАМН</institution><country>Russian Federation</country></aff><pub-date pub-type="collection"><year>2010</year></pub-date><pub-date pub-type="epub"><day>25</day><month>10</month><year>2025</year></pub-date><volume>0</volume><issue>2</issue><fpage>35</fpage><lpage>37</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Федосова Е.Ю., 2025</copyright-statement><copyright-year>2025</copyright-year><copyright-holder xml:lang="ru">Федосова Е.Ю.</copyright-holder><copyright-holder xml:lang="en">Fedosova E.J.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://ymj.elpub.ru/jour/article/view/2286">https://ymj.elpub.ru/jour/article/view/2286</self-uri><abstract><p>Исследовано содержание интерлейкина – 6 (IL-6), фактора некроза опухоли – α (ФНО-α), С-реактивного белка (СРБ) и прокальцитонина (ПКТ) в сыворотке крови 50 больных внебольничной пневмонией в различных клинико-морфологических группах. Выявлено достоверное повышение уровней IL-6, СРБ и ПКТ в 2-3раза по сравнению с показателями у практически здоровых лиц. Зафиксировано резкое повышение уровня прокальцитонина, СРБ в случаях присоединения инфекционных осложнений при внебольничной пневмании.</p></abstract><trans-abstract xml:lang="en"><p>The contents of interleukine - 6 (IL-6), the tumor necrosis factor - α (TNF- α), C- reactive protein (СRP) and procalcitonin (PCT) in blood serum of 50 patients with extra-hospital pneumonia in various clinical-morphological groups is investigated. Authentic increase of IL-6, СRP and PCT levels in 2-3 times in comparison with parameters in practically healthy persons is revealed. Sharp increase of PCT, CRP is recorded at connection of infectious complications at the extra-hospital pneumonia.</p></trans-abstract><kwd-group xml:lang="ru"><kwd>внебольничная пневмония</kwd><kwd>цитокины</kwd><kwd>прокальцитонин</kwd><kwd>С-реактивный белок</kwd><kwd>воспаление</kwd></kwd-group><kwd-group xml:lang="en"><kwd>extra-hospital pneumonia</kwd><kwd>cytokines</kwd><kwd>procalcitonin</kwd><kwd>C- reactive protein</kwd><kwd>inflammation</kwd></kwd-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Клиническая респираторная медицина / А.Г. Чучалин. – М, 2007. – С. 479-496.</mixed-citation><mixed-citation xml:lang="en">Клиническая респираторная медицина / А.Г. Чучалин. – М, 2007. – С. 479-496.</mixed-citation></citation-alternatives></ref><ref id="cit2"><label>2</label><citation-alternatives><mixed-citation xml:lang="ru">Система цитокинов и болезни органов дыхания / Б.И. 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