<?xml version="1.0" encoding="UTF-8"?>
<!DOCTYPE article PUBLIC "-//NLM//DTD JATS (Z39.96) Journal Publishing DTD v1.3 20210610//EN" "JATS-journalpublishing1-3.dtd">
<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">ymj</journal-id><journal-title-group><journal-title xml:lang="ru">Якутский медицинский журнал</journal-title><trans-title-group xml:lang="en"><trans-title>Yakut Medical Journal</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">1813-1905</issn><issn pub-type="epub">2312-1017</issn><publisher><publisher-name>ЯНЦ КМП</publisher-name></publisher></journal-meta><article-meta><article-id custom-type="elpub" pub-id-type="custom">ymj-2280</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>ОРИГИНАЛЬНЫЕ ИССЛЕДОВАНИЯ</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>ORIGINAL RESEARCH</subject></subj-group></article-categories><title-group><article-title>Интенсивность процессов перекисного окисления липидов и состояние антиоксидантной системы у больных в доинфекционную фазу панкреонекроза</article-title><trans-title-group xml:lang="en"><trans-title>Intensity of lipid peroxidation processes and a condition of antioxidant system in patients in pre-infection phase of pancreonecrosis</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Винокуров</surname><given-names>М. М.</given-names></name><name name-style="western" xml:lang="en"><surname>Vinokurov</surname><given-names>M. M.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Винокуров Михаил Михайлович – д.м.н., проф. зав. кафедрой</p></bio><email xlink:type="simple">mmv_mi@rambler.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Савельев</surname><given-names>В. В.</given-names></name><name name-style="western" xml:lang="en"><surname>Savelev</surname><given-names>V. V.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Савельев Вячеслав Васильевич – к.м.н., доцент</p></bio><email xlink:type="simple">vvsaveliev@mail.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Хлебный</surname><given-names>Е. С.</given-names></name><name name-style="western" xml:lang="en"><surname>Hlebnyj</surname><given-names>E. S.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Хлебный Ефим Сергеевич – к.б.н., н.с.</p></bio><xref ref-type="aff" rid="aff-2"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Кершенгольц</surname><given-names>Б. М.</given-names></name><name name-style="western" xml:lang="en"><surname>Kershengolts</surname><given-names>B. M.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Кершенгольц Борис Моисеевич – д.б.н, проф., акад. АН РС (Я), зав. лаб.</p></bio><email xlink:type="simple">kerschen@asrs.ysn.ru</email><xref ref-type="aff" rid="aff-2"/></contrib></contrib-group><aff xml:lang="ru" id="aff-1"><institution>МИ СВФУ им. М.К. Аммосова</institution><country>Russian Federation</country></aff><aff xml:lang="ru" id="aff-2"><institution>ИБПК СО РАН</institution><country>Russian Federation</country></aff><pub-date pub-type="collection"><year>2010</year></pub-date><pub-date pub-type="epub"><day>25</day><month>10</month><year>2025</year></pub-date><volume>0</volume><issue>2</issue><fpage>19</fpage><lpage>23</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Винокуров М.М., Савельев В.В., Хлебный Е.С., Кершенгольц Б.М., 2025</copyright-statement><copyright-year>2025</copyright-year><copyright-holder xml:lang="ru">Винокуров М.М., Савельев В.В., Хлебный Е.С., Кершенгольц Б.М.</copyright-holder><copyright-holder xml:lang="en">Vinokurov M.M., Savelev V.V., Hlebnyj E.S., Kershengolts B.M.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://ymj.elpub.ru/jour/article/view/2280">https://ymj.elpub.ru/jour/article/view/2280</self-uri><abstract><p>Проведен анализ результатов консервативного и хирургического лечения 123 больных в доинфекционную фазу панкреонекроза, с учетом комплексной оценки интенсивности нарушения процессов пероксидации, и состояния антиоксидантной системы.Отмечается повышение значения роли независимых предикторов воспаления в комплексной оценке прогноза заболевания и вероятности осложнения после проведенного оперативного вмешательства при остром деструктивном панкреатите.</p></abstract><trans-abstract xml:lang="en"><p>Analysis of results of conservative and surgical treatment of 123 patients before not infected phase of pancreatic necrosis, in view of a complex estimation of intensity of infringement peroxidation processes, and conditions antoxidation systems is carried out.Increase of value of a role of independent inflammation predictors in a complex estimation of the forecast of disease and probability of complication after the carried out operative intervention at acute destructive pancreatitis is marked.</p></trans-abstract><kwd-group xml:lang="ru"><kwd>стерильный панкреонекроз</kwd><kwd>перекисное окисление липидов</kwd><kwd>антиоксидантные системы</kwd></kwd-group><kwd-group xml:lang="en"><kwd>not infected pancreatic necrosis</kwd><kwd>lipid peroxidation</kwd><kwd>antioxidant systems</kwd></kwd-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Гельфанд Е.Б. Абдоминальный сепсис: интегральная оценка тяжести состояния больных и полиорганной дисфункции / Е.Б. Гельфанд, Б.Р. Гельфанд, В.А. Гологорский // Анест. и реаниматол. – 2000.– №3. – С. 29-33.</mixed-citation><mixed-citation xml:lang="en">Gelfand U.B. Abdominal sepsis: integral mark of gravity condition patients and poliorgan disfunction / U.B. Gelfand, B.R. Gelfand, V.A. Gologorsky // Anesth. and reanimathol. – 2000. – №3. – P. 29-33</mixed-citation></citation-alternatives></ref><ref id="cit2"><label>2</label><citation-alternatives><mixed-citation xml:lang="ru">Макарова Н.П. Синдром эндогенной интоксикации при сепсисе / Н.П. Макарова, И.Н. Коничева // Анест. и реаниматол.– 1995.– №6. – С. 4-6.</mixed-citation><mixed-citation xml:lang="en">Makarova N.P. Syndrome andogenic intocsication by sepsis / N.P. Makarova, I.N. Konicheva // Anesth. and reanimathol. – 1995. – №6. – P. 4-6.</mixed-citation></citation-alternatives></ref><ref id="cit3"><label>3</label><citation-alternatives><mixed-citation xml:lang="ru">Миронова Г.Е. Состояние антиоксидантной защиты при развитии хронического обструктивного бронхита и применение антиоксидантов в комплексной терапии больных в условиях Крайнего Севера: автореф. дис. … д-ра биол. наук / Г.Е. Миронова. – Москва., 2000. – 50 с.</mixed-citation><mixed-citation xml:lang="en">Mironova G.E. Condition antioxidant protection by chronic obstruction bronchitis and using antioxidant in complex therapy patients in the Far North: avtoref. dis. d-r biol. scientist / G.E. Mironova. – Moscow., 2000. – P.50</mixed-citation></citation-alternatives></ref><ref id="cit4"><label>4</label><citation-alternatives><mixed-citation xml:lang="ru">Потапов А.Ф. Комплексная интенсивная терапия хирургической абдоминальной инфекции в специализированном Центре экстренной медицинской помощи Республики Саха (Якутия): автореф. дис. … д-ра мед. наук / А.Ф. Потапов.– Москва., 2000. – 50 с.</mixed-citation><mixed-citation xml:lang="en">Potapov A.F. Complex intensive therapy surgical abdominal infection in specialized urgent medical centre the republic of Sakha (Yakutia): avtoref. dis. d-r med. scientist / Potapov A.F. – Moscow., 2000. – P. 50.</mixed-citation></citation-alternatives></ref><ref id="cit5"><label>5</label><citation-alternatives><mixed-citation xml:lang="ru">Рогожин В.В. Методы биохимических исследований / В.В. Рогожин. – Якутск, 1998.– 93 с.</mixed-citation><mixed-citation xml:lang="en">Rogojin V.V. Methods biochemical research / V.V. Rogojin. – Yakutsk – , 1998.– P.93.</mixed-citation></citation-alternatives></ref><ref id="cit6"><label>6</label><citation-alternatives><mixed-citation xml:lang="ru">Савельев В.С. Системная воспалительная реакция и сепсис при панкреонекрозе / В.С. Савельев, Б.Р. Гельфанд, В.А. Гологорский // Анест. и реаниматол.– 1999. – №6. – С. 28-33.</mixed-citation><mixed-citation xml:lang="en">Saveliev V.S. System inflammation reaction and sepsis by pancreatic necrosis / V.S. Saveliev, B.R. Gelfand, V.A. Gologorsky // Anesth. and reanimathol.– 1999. – №6. – P. 28-33.</mixed-citation></citation-alternatives></ref><ref id="cit7"><label>7</label><citation-alternatives><mixed-citation xml:lang="ru">Толстой А.Д. Деструктивный панкреатит и парапанкреатит / А.Д. Толстой, Р.А. Сопия, В.Б. Красногоров. – СПб.: Изд-во «Гиппократ»,1999.– 128 с.</mixed-citation><mixed-citation xml:lang="en">Tolstoy A.D. Destructivity pancreatitis and parapancreatitis / A.D. Tolstoy, R.A. Sopiay, V.B. Krasnogorov. – St. Petersburg.: state publishing «Hippokrat», 1999.– P. 128.</mixed-citation></citation-alternatives></ref><ref id="cit8"><label>8</label><citation-alternatives><mixed-citation xml:lang="ru">Constantine N.G. Method of determination superoxydismutase in blood / N.G. Constantine // Plant. Physiol.– 1977.– Vol.59.– P.565-569.</mixed-citation><mixed-citation xml:lang="en">Constantine N.G. Method of determination superoxydismutase in blood / N.G. Constantine // Plant. Physiol.– 1977.– Vol.59.– P.565-569.</mixed-citation></citation-alternatives></ref><ref id="cit9"><label>9</label><citation-alternatives><mixed-citation xml:lang="ru">Demling R.N. Endotoxaemia cause increased lung tissue lipid peroxidation in unanaestetised sleep / R.N. Demling, С.F. Laloude, L-J. Jin // Appl. Phys.-1986.– Vol.60.– P.2094-2100.</mixed-citation><mixed-citation xml:lang="en">Demling R.N. Endotoxaemia cause increased lung tissue lipid peroxidation in unanaestetised sleep / R.N. Demling, С.F. Laloude, L-J. Jin // Appl. Phys.-1986.– Vol.60.– P.2094-2100.</mixed-citation></citation-alternatives></ref></ref-list><fn-group><fn fn-type="conflict"><p>The authors declare that there are no conflicts of interest present.</p></fn></fn-group></back></article>
