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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">ymj</journal-id><journal-title-group><journal-title xml:lang="ru">Якутский медицинский журнал</journal-title><trans-title-group xml:lang="en"><trans-title>Yakut Medical Journal</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">1813-1905</issn><issn pub-type="epub">2312-1017</issn><publisher><publisher-name>ЯНЦ КМП</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="doi">10.25789/YMJ.2024.88.22</article-id><article-id custom-type="elpub" pub-id-type="custom">ymj-227</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>НАУЧНЫЕ ОБЗОРЫ</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>SCIENTIFIC REVIEWS</subject></subj-group></article-categories><title-group><article-title>Послеоперационная когнитивная дисфункция: определение, классификация и факторы риска</article-title><trans-title-group xml:lang="en"><trans-title>Postoperative cognitive dysfunction: definition, classification and risk factors</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-4159-500X</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Таппахов</surname><given-names>А. А.</given-names></name><name name-style="western" xml:lang="en"><surname>Tappakhov</surname><given-names>A. A.</given-names></name></name-alternatives><bio xml:lang="ru"><p> Таппахов Алексей Алексеевич – к.м.н., доцент, с.н.с. </p><p> Якутск </p></bio><email xlink:type="simple">dralex89@mail.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Лукачевская</surname><given-names>Я. А.</given-names></name><name name-style="western" xml:lang="en"><surname>Lukachevskaya</surname><given-names>Ya. A.</given-names></name></name-alternatives><bio xml:lang="ru"><p> Лукачевская Яна Анатольевна – врач-анестезиолог-реаниматолог  </p><p> Якутск </p></bio><email xlink:type="simple">lukachevskaya@list.ru</email><xref ref-type="aff" rid="aff-2"/></contrib></contrib-group><aff xml:lang="ru" id="aff-1"><institution>Медицинский институт СВФУ им. М.К. Аммосова; Центр нейродегенеративных заболеваний ЯНЦ КМП</institution><country>Russian Federation</country></aff><aff xml:lang="ru" id="aff-2"><institution>Республиканская больница №2-ЦЭМП</institution><country>Russian Federation</country></aff><pub-date pub-type="collection"><year>2024</year></pub-date><pub-date pub-type="epub"><day>06</day><month>02</month><year>2025</year></pub-date><volume>0</volume><issue>4</issue><fpage>93</fpage><lpage>98</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Таппахов А.А., Лукачевская Я.А., 2025</copyright-statement><copyright-year>2025</copyright-year><copyright-holder xml:lang="ru">Таппахов А.А., Лукачевская Я.А.</copyright-holder><copyright-holder xml:lang="en">Tappakhov A.A., Lukachevskaya Y.A.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://ymj.elpub.ru/jour/article/view/227">https://ymj.elpub.ru/jour/article/view/227</self-uri><abstract><p>На основании обзора литературы выделены ведущие факторы риска развития послеоперационного делирия (ПОД) и собственно послеоперационной когнитивной дисфункции (ПОКД), подчеркнуты факторы, способные снизить вероятность наступления когнитивных нарушений после перенесенных операций. Обсуждаются патофизиологические механизмы, способствующие развитию ПОКД. Авторами установлено, что ПОКД и ПОД являются значимой клинической проблемой, которая требует междисциплинарные усилия и комплексный подход к диагностике, лечению и профилактике.</p></abstract><trans-abstract xml:lang="en"><p>Based on a literature review, leading risk factors for the development of both postoperative delirium (POD) and POCD itself have been identified, and factors that can reduce the likelihood of cognitive impairment after surgery have been highlighted. The pathophysiological mechanisms contributing to the development of POCD are discussed. The authors have established that POCD and POD are significant clinical problems requiring interdisciplinary efforts and a comprehensive approach to diagnosis, treatment, and prevention.</p></trans-abstract><kwd-group xml:lang="ru"><kwd>послеоперационная когнитивная дисфункция</kwd><kwd>послеоперационные делирий</kwd><kwd>оперативное вмешательство</kwd><kwd>анестетики</kwd><kwd>когнитивные нарушения</kwd><kwd>деменция</kwd></kwd-group><kwd-group xml:lang="en"><kwd>postoperative cognitive dysfunction</kwd><kwd>postoperative delirium</kwd><kwd>surgery</kwd><kwd>anesthetics</kwd><kwd>cognitive impairment</kwd><kwd>dementia</kwd></kwd-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Здравоохранение в России. 2023: Статистический сборник. М.: Росстат, 2023. 179 с.</mixed-citation><mixed-citation xml:lang="en">Healthcare in Russia. 2023: Statistical Digest. 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