<?xml version="1.0" encoding="UTF-8"?>
<!DOCTYPE article PUBLIC "-//NLM//DTD JATS (Z39.96) Journal Publishing DTD v1.3 20210610//EN" "JATS-journalpublishing1-3.dtd">
<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">ymj</journal-id><journal-title-group><journal-title xml:lang="ru">Якутский медицинский журнал</journal-title><trans-title-group xml:lang="en"><trans-title>Yakut Medical Journal</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">1813-1905</issn><issn pub-type="epub">2312-1017</issn><publisher><publisher-name>ЯНЦ КМП</publisher-name></publisher></journal-meta><article-meta><article-id custom-type="elpub" pub-id-type="custom">ymj-2184</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>ОРИГИНАЛЬНЫЕ ИССЛЕДОВАНИЯ</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>ORIGINAL RESEARCH</subject></subj-group></article-categories><title-group><article-title>Клиническая и бактериологическая оценка эффективности антибактериальной терапии у больных с абдоминальной нозокомиальной инфекцией в отделении реанимации и интенсивной терапии</article-title><trans-title-group xml:lang="en"><trans-title>Clinical and bacteriological assessment of antibacterial therapy efficacy in patients with abdominal nosocomial infection in intensive сare unit</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Гаврильев</surname><given-names>С. Н.</given-names></name><name name-style="western" xml:lang="en"><surname>Gavriliev</surname><given-names>S. N.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Гаврильев Семен Николаевич – аспирант МИ</p></bio><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Матвеев</surname><given-names>А. С.</given-names></name><name name-style="western" xml:lang="en"><surname>Matveev</surname><given-names>A. S.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Матвеев Афанасий Семенович – к.м.н., доцент ИПОВ, врач анестезиолог-реаниматолог</p></bio><email xlink:type="simple">alanay-mac71@rambler.ru</email><xref ref-type="aff" rid="aff-2"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Потапов</surname><given-names>А. Ф.</given-names></name><name name-style="western" xml:lang="en"><surname>Potapov</surname><given-names>A. F.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Потапов Александр Филиппович – д.м.н., проф., зав. кафедрой</p></bio><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Игнатьев</surname><given-names>В. Г.</given-names></name><name name-style="western" xml:lang="en"><surname>Ignatiev</surname><given-names>V. G.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Игнатьев Виктор Георгиевич – д.м.н., проф., зав.кафедрой МИ</p></bio><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Голубев</surname><given-names>А. М.</given-names></name><name name-style="western" xml:lang="en"><surname>Golubev</surname><given-names>A. M.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Голубев Аркадий Михайлович – д.м.н., проф., зам. директора по науке</p></bio><xref ref-type="aff" rid="aff-3"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Мороз</surname><given-names>В. В.</given-names></name><name name-style="western" xml:lang="en"><surname>Moroz</surname><given-names>V. V.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Мороз Виктор Васильевич – д.м.н., проф., чл.-кор. РАМН, директор</p></bio><xref ref-type="aff" rid="aff-3"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Решетняк</surname><given-names>В. И.</given-names></name><name name-style="western" xml:lang="en"><surname>Reshetnyak</surname><given-names>V. I.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Решетняк Василий Иванович – д.м.н., проф., уч. секретарь диссертационного совета</p></bio><xref ref-type="aff" rid="aff-3"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Шамаева</surname><given-names>С. Х.</given-names></name><name name-style="western" xml:lang="en"><surname>Shamaeva</surname><given-names>S. Kh.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Шамаева Степанида Харитоновна – к.б.н., зав. клинич. бактериологич. лаб.</p></bio><xref ref-type="aff" rid="aff-4"/></contrib></contrib-group><aff xml:lang="ru" id="aff-1"><institution>МИ СВФУ им. М.К. Аммосова</institution><country>Russian Federation</country></aff><aff xml:lang="ru" id="aff-2"><institution>РБ №2-ЦЭМП;&#13;
МИ СВФУ им. М.К. Аммосова</institution><country>Russian Federation</country></aff><aff xml:lang="ru" id="aff-3"><institution>УРАМН НИИ общей реаниматологии им. В.А. Неговского РАМН</institution><country>Russian Federation</country></aff><aff xml:lang="ru" id="aff-4"><institution>УРАМН НИИ общей реаниматологии им. В.А. Неговского РАМН;&#13;
РБ №2-ЦЭМП МЗ РС(Я)</institution><country>Russian Federation</country></aff><pub-date pub-type="collection"><year>2011</year></pub-date><pub-date pub-type="epub"><day>19</day><month>10</month><year>2025</year></pub-date><volume>0</volume><issue>4</issue><fpage>45</fpage><lpage>48</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Гаврильев С.Н., Матвеев А.С., Потапов А.Ф., Игнатьев В.Г., Голубев А.М., Мороз В.В., Решетняк В.И., Шамаева С.Х., 2025</copyright-statement><copyright-year>2025</copyright-year><copyright-holder xml:lang="ru">Гаврильев С.Н., Матвеев А.С., Потапов А.Ф., Игнатьев В.Г., Голубев А.М., Мороз В.В., Решетняк В.И., Шамаева С.Х.</copyright-holder><copyright-holder xml:lang="en">Gavriliev S.N., Matveev A.S., Potapov A.F., Ignatiev V.G., Golubev A.M., Moroz V.V., Reshetnyak V.I., Shamaeva S.K.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://ymj.elpub.ru/jour/article/view/2184">https://ymj.elpub.ru/jour/article/view/2184</self-uri><abstract><p>Нозокомиальные инфекции являются ведущей причиной летальности в отделениях реанимации и интенсивной терапии хирургического профиля. Сложности их лечения обусловлены ростом устойчивости возбудителей. В связи с этим необходим пересмотр формуляра антибиотикотерапии с учетом клинической и бактериологической оценки эффективности и создания схем антибактериальных препаратов в РБ №2-ЦЭМП.</p></abstract><trans-abstract xml:lang="en"><p>Nosocomial infections are the main reasons of death rates in intensive care unit and intensive therapy of surgical profile. The growth of pathogen resistance causes treatment complications. Therefore, reconsider of antibiotics formulary should be done taking into an account clinical and bacteriological estimation of effectiveness and creating plans of antibacterial preparations at Republics Hospital № 2 –Center of Urgent Medical Aid.</p></trans-abstract><kwd-group xml:lang="ru"><kwd>нозокомиальная абдоминальная инфекция</kwd><kwd>эмпирическая антибактериальная терапия</kwd><kwd>ОРИТ</kwd></kwd-group><kwd-group xml:lang="en"><kwd>nosocomial abdominal infection</kwd><kwd>empirical antibacterial therapy</kwd><kwd>ICU</kwd></kwd-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Антибиотикопрофилактика, антибиотикотерапия и микробиологическая ситуация в хирургическом стационаре / В.Н. Оболенский [и др.] //Антибиотики и химиотерапия. – 2004. – Т. 49, №10. – С.12 – 19.</mixed-citation><mixed-citation xml:lang="en">Antibiotics preventions, antibiotics therapy and a microbiological situation in a surgical hospital / Obolensky V.N. [et al.]. //Antibiotics and chemotherapy. – 2004. – volume 49. – №10. – С.12 – 19.</mixed-citation></citation-alternatives></ref><ref id="cit2"><label>2</label><citation-alternatives><mixed-citation xml:lang="ru">Европейское руководство по клинической оценке противоинфекционных лекарственных средств. /Под ред. T.R.Beam, D.N.Gilbert, C.M.Kunin; пер. с англ. под ред. А.Г. Чучалина, Л.С. Страчунского). – Смоленск: «Амипресс», 1996. – С.15 – 40.</mixed-citation><mixed-citation xml:lang="en">The European management of a clinical estimation of anti-infectious medical products. / T.R.Beam, D.N.Gilbert, C.M.Kunin. Tran. from Engl. A.G.Chuchalin, L.S. Strachunsky). – Smolensk. – “Amipress”. – 1996. – p.15 – 40.</mixed-citation></citation-alternatives></ref><ref id="cit3"><label>3</label><citation-alternatives><mixed-citation xml:lang="ru">Матвеев А.С. Антибактериальная терапия у хирургических больных с нозокомиальной абдоминальной инфекцией: дисс. …канд. мед. наук /А.С. Матвеев. – М., 2010. – 156 с.</mixed-citation><mixed-citation xml:lang="en">Matveev A.S. Antibacterial therapy of surgical patients with Nosocomial abdominal infection: PLD thesis. A.S. Matveev. – M., 2010. –p.156.</mixed-citation></citation-alternatives></ref><ref id="cit4"><label>4</label><citation-alternatives><mixed-citation xml:lang="ru">Потапов А.Ф. Комплексная интенсивная терапия хирургической абдоминальной инфекции в специализированном центре экстренной медицинской помощи Республики Саха (Якутия): автореф.дисс. …д-ра мед. наук / А.Ф. Потапов. – М., 2004. – 46 с.</mixed-citation><mixed-citation xml:lang="en">Potapov A.F. Complex intensive therapy of surgical аbdominal infection in the specialized center of emergency medical aid Republic Sakha (Yakutia): аutoreport.diss. … doc.med.sciences/ A.F. Potapov. – M/, 2004. – 46 with.</mixed-citation></citation-alternatives></ref><ref id="cit5"><label>5</label><citation-alternatives><mixed-citation xml:lang="ru">Сепсис: клинико-патофизиологические аспекты интенсивной терапии / В.В. Мороз [и др.]. – Петрозаводск: ИнтелТек, 2004. – 291 с.</mixed-citation><mixed-citation xml:lang="en">Sepsis: Clinicv-pathophysiological aspects of intensive therapy / V.V.Moroz [et al.]. – Petrozavodsk: Inteltec, 2004 – p.291.</mixed-citation></citation-alternatives></ref><ref id="cit6"><label>6</label><citation-alternatives><mixed-citation xml:lang="ru">Сидоренко С.В. Инфекции в интенсивной терапии. 2-е изд., перераб. и доп. / С.В. Сидоренко, С.В. Яковлев. – М.: Издательство «Бионика», 2003. – 208 с.</mixed-citation><mixed-citation xml:lang="en">Sidorenko S.V. Infection in intensive therapy. 2 pub., the rework. And addit / S.V. Sidorenko, S.V. Jakovlev. – М: Publishing house “Bionics«, 2003. – 208 .</mixed-citation></citation-alternatives></ref><ref id="cit7"><label>7</label><citation-alternatives><mixed-citation xml:lang="ru">Early removal of prophylactic drains reduces the risk of intra-abdominal infections in patients with pancreatic head resection: prospective study for 104 consecutive patients / M. Kawai [et al.] // Annals of Surgery. - 2006. – 244(1). – P.1-7.</mixed-citation><mixed-citation xml:lang="en">Early removal of prophylactic drains reduces the risk of intra-abdominal infections in patients with pancreatic head resection: prospective study for 104 consecutive patients / M. Kawai [et al.] // Annals of Surgery. - 2006. – 244(1). – P.1-7.</mixed-citation></citation-alternatives></ref><ref id="cit8"><label>8</label><citation-alternatives><mixed-citation xml:lang="ru">Impact of restriction of third gereration cephalosporins on the burden of third generation cephalosporin resistant K.pneumoniae and E.coliin an ICU / E. Meyer [et al.] // Intensive Care Med. – 2009. – 35(5). – P.862 – 870.</mixed-citation><mixed-citation xml:lang="en">Impact of restriction of third gereration cephalosporins on the burden of third generation  cephalosporin resistant K.pneumoniae and E.coliin an ICU / E. Meyer [et al.] // Intensive Care Med. – 2009. – 35(5). – P.862 – 870.</mixed-citation></citation-alternatives></ref><ref id="cit9"><label>9</label><citation-alternatives><mixed-citation xml:lang="ru">Mortality for intra-abdominal infection is associated with intrinsic risk factors rather than the source of infection / T. Inui [et al.] // Surgery.- 2009. - 146(4). – P.654-662.</mixed-citation><mixed-citation xml:lang="en">Mortality for intra-abdominal infection is associated with intrinsic risk factors rather than the source of infection / T. Inui [et al.] // Surgery.- 2009. - 146(4). – P.654-662.</mixed-citation></citation-alternatives></ref><ref id="cit10"><label>10</label><citation-alternatives><mixed-citation xml:lang="ru">Risk factors and management of intraabdominal infection after extended radical gastrectomy / C.H. Lo [et al.] // Am J Surg. - 2008. - 196(5). – P.741-745.</mixed-citation><mixed-citation xml:lang="en">Risk factors and management of intraabdominal infection after extended radical gastrectomy / C.H. Lo [et al.] // Am J Surg. - 2008. - 196(5). – P.741-745.</mixed-citation></citation-alternatives></ref></ref-list><fn-group><fn fn-type="conflict"><p>The authors declare that there are no conflicts of interest present.</p></fn></fn-group></back></article>
