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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">ymj</journal-id><journal-title-group><journal-title xml:lang="ru">Якутский медицинский журнал</journal-title><trans-title-group xml:lang="en"><trans-title>Yakut Medical Journal</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">1813-1905</issn><issn pub-type="epub">2312-1017</issn><publisher><publisher-name>ЯНЦ КМП</publisher-name></publisher></journal-meta><article-meta><article-id custom-type="elpub" pub-id-type="custom">ymj-2107</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>ОРИГИНАЛЬНЫЕ ИССЛЕДОВАНИЯ</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>ORIGINAL RESEARCH</subject></subj-group></article-categories><title-group><article-title>Метаболические нарушения у женщин с дисфункцией гипоталамуса в репродуктивном возрасте</article-title><trans-title-group xml:lang="en"><trans-title>Metabolic disorders in women with dysfunction of the hypothalamus in reproductive age</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Жуковец</surname><given-names>И. В.</given-names></name><name name-style="western" xml:lang="en"><surname>Zhukovets</surname><given-names>I. V.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Жуковец Ирина Валентиновна – к.м.н., доцент</p></bio><bio xml:lang="en"><p>Zhukovets Irina V., PhD, Associate Professor of Obstetrics and Gynecology</p><p>t.sot. 89143811706</p></bio><email xlink:type="simple">zhukovec040875@mail.ru</email><xref ref-type="aff" rid="aff-1"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru"><institution>Амурская государственная медицинская академия</institution><country>Россия</country></aff><aff xml:lang="en"><institution>State Medical Amur State Medical Academy</institution><country>Russian Federation</country></aff></aff-alternatives><pub-date pub-type="collection"><year>2011</year></pub-date><pub-date pub-type="epub"><day>18</day><month>10</month><year>2025</year></pub-date><volume>0</volume><issue>2</issue><fpage>14</fpage><lpage>16</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Жуковец И.В., 2025</copyright-statement><copyright-year>2025</copyright-year><copyright-holder xml:lang="ru">Жуковец И.В.</copyright-holder><copyright-holder xml:lang="en">Zhukovets I.V.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://ymj.elpub.ru/jour/article/view/2107">https://ymj.elpub.ru/jour/article/view/2107</self-uri><abstract><p>Изучены метаболические нарушения у 185 женщин с дисфункцией гипоталамуса (ДГ). Результаты сопоставимы с аналогичными у женщин без эндокринных нарушений. У женщин с ДГ отмечается увеличение индекса массы тела, абдоминальный тип ожирения. На фоне бесплодия выявлены нарушения менструального цикла, снижение уровня прогестерона во 2-ю фазу менструального цикла. У каждой четвертой обследуемой отмечались нарушения толерантности к глюкозе, инсулинорезистентность и снижение ЛПВП. Своевременная диагностика и коррекция метаболических нарушений позволит улучшить репродуктивный прогноз.</p></abstract><trans-abstract xml:lang="en"><p>Metabolic disorders at 185 women with DH are studied. The results are comparable with similar at women without endocrinal disorders. At women with DH the increase in an index of body mass, abdominal type of obesity is marked. Against barrenness menstrual cycle disorders, lowering of progesterone level in the 2 phase of the menstrual cycle are revealed. At every fourth surveyed glucose tolerance disorders, insulin resistance and LPVP decrease are marked. Timely diagnostics and correction of metabolic disorders will allow to improve the reproductive prognosis.</p></trans-abstract><kwd-group xml:lang="ru"><kwd>дисфункция гипоталамуса</kwd><kwd>метаболические нарушения</kwd></kwd-group><kwd-group xml:lang="en"><kwd>dysfunction of the hypothalamus</kwd><kwd>metabolic disorders</kwd></kwd-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Артемук Н.В., Крапивина Н.А., Тачкова О.А. Пищевое поведение и репродуктивные проблемы женщин с ожирением // Акушерство и гинекология. – 2010. - №5. – С.34-37.</mixed-citation><mixed-citation xml:lang="en">Artemuk N.V. Krapivina N.A., Tachkova O.A. 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