<?xml version="1.0" encoding="UTF-8"?>
<!DOCTYPE article PUBLIC "-//NLM//DTD JATS (Z39.96) Journal Publishing DTD v1.3 20210610//EN" "JATS-journalpublishing1-3.dtd">
<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">ymj</journal-id><journal-title-group><journal-title xml:lang="ru">Якутский медицинский журнал</journal-title><trans-title-group xml:lang="en"><trans-title>Yakut Medical Journal</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">1813-1905</issn><issn pub-type="epub">2312-1017</issn><publisher><publisher-name>ЯНЦ КМП</publisher-name></publisher></journal-meta><article-meta><article-id custom-type="elpub" pub-id-type="custom">ymj-2095</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>ТОЧКА ЗРЕНИЯ</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>POINT OF VIEW</subject></subj-group></article-categories><title-group><article-title>Высокая частота артериальной гипертензии и поражение органов мишеней у коренных жителей Якутии с верифицированным атеросклерозом коронарных артерий – возможная связь с инсулинорезистентностью</article-title><trans-title-group xml:lang="en"><trans-title>High frequency of arterial hypertension and affection of target organs in the natives of Yakutia with verified coronary atherosclerosis - possible links with insulin resistance</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Махарова</surname><given-names>Н. В.</given-names></name><name name-style="western" xml:lang="en"><surname>Maharova</surname><given-names>N. V.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Махарова Наталья Владимировна – д.м.н., с.н.с.</p></bio><bio xml:lang="en"><p>Republic Sakha (Yakutia)</p></bio><email xlink:type="simple">Makharova@mail.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Воевода</surname><given-names>М. И.</given-names></name><name name-style="western" xml:lang="en"><surname>Voevoda</surname><given-names>M. I.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Воевода Михаил Иванович – д.м.н., проф., чл.-кор. РАМН, директор</p><p>Новосибирск</p></bio><bio xml:lang="en"><p>Novosibirsk</p></bio><xref ref-type="aff" rid="aff-2"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Лютова</surname><given-names>Ф. Ф.</given-names></name><name name-style="western" xml:lang="en"><surname>Ljutova</surname><given-names>F. F.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Лютова Фаина Федоровна – к.м.н., с.н.с.</p></bio><bio xml:lang="en"><p>Novosibirsk</p></bio><xref ref-type="aff" rid="aff-2"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru">ЯНЦ КМП СО РАМН<country>Россия</country></aff><aff xml:lang="en">Yakut Research Centre of complex medical problems of the Siberian Branch of the Russian Academy of Medical Sciences<country>Russian Federation</country></aff></aff-alternatives><aff-alternatives id="aff-2"><aff xml:lang="ru">НИИ терапии СО РАМН<country>Россия</country></aff><aff xml:lang="en">Scientific-Research Therapy Institute of the Siberian Branch of the Russian Academy of Medical Sciences<country>Russian Federation</country></aff></aff-alternatives><pub-date pub-type="collection"><year>2011</year></pub-date><pub-date pub-type="epub"><day>18</day><month>10</month><year>2025</year></pub-date><volume>0</volume><issue>1</issue><fpage>104</fpage><lpage>107</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Махарова Н.В., Воевода М.И., Лютова Ф.Ф., 2025</copyright-statement><copyright-year>2025</copyright-year><copyright-holder xml:lang="ru">Махарова Н.В., Воевода М.И., Лютова Ф.Ф.</copyright-holder><copyright-holder xml:lang="en">Maharova N.V., Voevoda M.I., Ljutova F.F.</copyright-holder><license license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://ymj.elpub.ru/jour/article/view/2095">https://ymj.elpub.ru/jour/article/view/2095</self-uri><abstract><p>Проведено сопоставление данных селективной ангиографии, мультиспиральной компьютерной томографии и факторов риска у больных атеросклерозом коронарных артерий. Анализ факторов риска у больных выявил, что среди мужчин коренного населения Якутии при меньшей выраженности атеросклероза коронарных артерий, низких значениях атерогенных липидов, меньшей частоте ожирения (по критерию ИМТ) выявлена большая частота артериальной гипертензии и связанная с ней гипертрофия левых отделов сердца.</p></abstract><trans-abstract xml:lang="en"><p>A comparison of the data of selective angiography, computed tomography and risk factors in patients with coronary atherosclerosis is carried out. Analysis of risk factors in patients revealed that among indigenous men at less severity of coronary artery atherosclerosis, low values of atherogR .</p></trans-abstract><kwd-group xml:lang="ru"><kwd>атеросклероз коронарных артерий</kwd><kwd>факторы риска</kwd><kwd>артериальная гипертензия</kwd><kwd>гипертрофия левых отделов сердца</kwd><kwd>коренные и некоренные жители Республики Саха (Якутия)</kwd></kwd-group><kwd-group xml:lang="en"><kwd>atherosclerosis of coronary arteries</kwd><kwd>risk factor</kwd><kwd>arterial hypertension</kwd><kwd>myocardial hypertrophy</kwd><kwd>indigenous and non-indigenous people of Republic Sakha (Yakutia)</kwd></kwd-group><funding-group xml:lang="ru"><funding-statement>Исследование проведено при поддержке Грантов «Интеграция науки и высшего образования России» (2005 г.), Президента Республики Саха (Якутия) (2007), «Лига здоровья нации» (2008 г.).</funding-statement></funding-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Агаджанян Н.А. Экологический портрет человека на Севере / Н.А. Агаджанян, Н.В. Ермаков – М.: Медицина; 1997. – 253 с.</mixed-citation><mixed-citation xml:lang="en">Aghajanian N.A. Environmental portrait of a man in the North / N.A. Aghajanian, N.V. Ermakov - M.: Medicine, 1997. – 253 p. (Russian).</mixed-citation></citation-alternatives></ref><ref id="cit2"><label>2</label><citation-alternatives><mixed-citation xml:lang="ru">Аргунов В.А. О результатах изучения атеросклероза аорты и коронарных артерий за 40-летний период / В.А. Аргунов // Экология и здоровье человека на Севере: мат. респ. конф. – Якутск, 2007. – с. 62.</mixed-citation><mixed-citation xml:lang="en">Argunov V.A. The results of the study of atherosclerosis of aorta and coronary arteries of 40-year period / V.A. Argunov / / Environmental and Human Health in the North: Math. rep. Conf. - Yakutsk, 2007. - p. 62 (Russian).</mixed-citation></citation-alternatives></ref><ref id="cit3"><label>3</label><citation-alternatives><mixed-citation xml:lang="ru">Зимин Ю.В. Инсулинорезистентность, гиперинсулинемия и артериальная гипертония / Ю.В. Зимин // Кардиология. – 1996. – № 11. – С. 80-91.</mixed-citation><mixed-citation xml:lang="en">Zimin Y. Insulin resistance, hyperinsulinemia and hypertension / Y. Zimin / / Cardiology. - 1996. - № 11. - P. 80-91.</mixed-citation></citation-alternatives></ref><ref id="cit4"><label>4</label><citation-alternatives><mixed-citation xml:lang="ru">Игнатьев П.М. Сахарный диабет в Республике Саха (Якутия) (по данным регистра) / П.М. Игнатьев, М.А. Федорова // Якутский медицинский журнал. – 2004. – №2(6). – С. 25-26.</mixed-citation><mixed-citation xml:lang="en">Ignatiev P.M. Diabetes mellitus in the Republic Sakha (Yakutia) (according to the register) / P.M. Ignatiev, M.A. Fedorova / Yakutsk Medical Journal. - 2004. - № 2 (6). -P. 25-26.</mixed-citation></citation-alternatives></ref><ref id="cit5"><label>5</label><citation-alternatives><mixed-citation xml:lang="ru">Метаболический синдром у аборигенного населения Якутии / В.Л. Осаковский [и др.] // Якутский мед. журнал. – 2010. – №2(30). – С. 98-102.</mixed-citation><mixed-citation xml:lang="en">Metabolic syndrome in aboriginal populations of Yakutia / V.L. Osakovsky [et. al.] / / Yakutsk Medical Journal . - 2010. - № 2 (30). - P. 98-102.</mixed-citation></citation-alternatives></ref><ref id="cit6"><label>6</label><citation-alternatives><mixed-citation xml:lang="ru">Arterial hypertension, myocardial infarction and stroke: risk of development and psychosocial factors / V.V. Gafarov [et.al.] //Alaska Med. – 2007. – № 49(2 Suppl). – P. 117-119.</mixed-citation><mixed-citation xml:lang="en">Arterial hypertension, myocardial infarction and stroke: risk of development and psychosocial factors / V.V. Gafarov [et.al.] //Alaska Med. – 2007. – № 49(2 Suppl). – P. 117-119.</mixed-citation></citation-alternatives></ref><ref id="cit7"><label>7</label><citation-alternatives><mixed-citation xml:lang="ru">Health consequences of postsoviet transition: dietary and lifestyle determinants of plasma lipids in Yakutia / M.V. Sorensen, J.J. // Am J Hum Biol. – 2005. – №17(5). – Р. 576-592.</mixed-citation><mixed-citation xml:lang="en">Health consequences of postsoviet transition: dietary and lifestyle determinants of plasma lipids in Yakutia / M.V. Sorensen, J.J. // Am J Hum Biol. – 2005. – №17(5). – Р. 576-592.</mixed-citation></citation-alternatives></ref><ref id="cit8"><label>8</label><citation-alternatives><mixed-citation xml:lang="ru">Heliogeophysical disturbances and exacerbations of cardiovascular disease. / S.N. Samsonov [at al.] // Zh Nevrol Psikhiatr Im S S Korsakova. – 2005. – (Suppl 14). – Р. 18-22.</mixed-citation><mixed-citation xml:lang="en">Heliogeophysical disturbances and exacerbations of cardiovascular disease. / S.N. Samsonov [at al.] // Zh Nevrol Psikhiatr Im S S Korsakova. – 2005. – (Suppl 14). – Р. 18-22.</mixed-citation></citation-alternatives></ref><ref id="cit9"><label>9</label><citation-alternatives><mixed-citation xml:lang="ru">Lifestyle incongruity, stress and immune function in indigenous Siberians: the health impacts of rapid social and economic change / M.V. Sorensen [at al.] // Am J Phys Anthropol. – 2009. – №138(1). – P. 62-69.</mixed-citation><mixed-citation xml:lang="en">Lifestyle incongruity, stress and immune function in indigenous Siberians: the health impacts of rapid social and economic change / M.V. Sorensen [at al.] // Am J Phys Anthropol. – 2009. – №138(1). – P. 62-69.</mixed-citation></citation-alternatives></ref><ref id="cit10"><label>10</label><citation-alternatives><mixed-citation xml:lang="ru">Manchuk VT. Alaska Ethnic and environmental factors in health formation in the Siberian population / V.T. Manchuk . J. Med. –2007. – № 49(2 Suppl). – P. 14-15.</mixed-citation><mixed-citation xml:lang="en">Manchuk VT. Alaska Ethnic and environmental factors in health formation in the Siberian population / V.T. Manchuk . J. Med. –2007. – № 49(2 Suppl). – P. 14-15.</mixed-citation></citation-alternatives></ref><ref id="cit11"><label>11</label><citation-alternatives><mixed-citation xml:lang="ru">Petrova P.G. Ecology and community health in the North / P.G. Petrova, N.P. Yakovleva, F.A. Zakharova // Int J Circumpolar Health. – 2001. – № 60(2). – Р. 170-177.</mixed-citation><mixed-citation xml:lang="en">Petrova P.G. Ecology and community health in the North / P.G. Petrova, N.P. Yakovleva, F.A. Zakharova // Int J Circumpolar Health. – 2001. – № 60(2). – Р. 170-177.</mixed-citation></citation-alternatives></ref><ref id="cit12"><label>12</label><citation-alternatives><mixed-citation xml:lang="ru">Rumberger J.A Coronary artery calcium areas by electron beam computed tomography and coronary atherosclerotic plague area: a histopathology correlative study / J.A. Rumberger, D.B. Simons, L.A. [at al.] // Circulation. – 1995. – № 92. – P. 2157-2162.</mixed-citation><mixed-citation xml:lang="en">Rumberger J.A Coronary artery calcium areas by electron beam computed tomography and coronary atherosclerotic plague area: a histopathology correlative study / J.A. Rumberger, D.B. Simons, L.A. [at al.] // Circulation. – 1995. – № 92. – P. 2157-2162.</mixed-citation></citation-alternatives></ref><ref id="cit13"><label>13</label><citation-alternatives><mixed-citation xml:lang="ru">The influence of basal metabolic rate on blood pressure among indigenous Siberians / J.J. Snodgrass [at al.] // Am J Phys Anthropol. – 2008. – №137(2). – P. 145-55.</mixed-citation><mixed-citation xml:lang="en">The influence of basal metabolic rate on blood pressure among indigenous Siberians / J.J. Snodgrass [at al.] // Am J Phys Anthropol. – 2008. – №137(2). – P. 145-55.</mixed-citation></citation-alternatives></ref></ref-list><fn-group><fn fn-type="conflict"><p>The authors declare that there are no conflicts of interest present.</p></fn></fn-group></back></article>
