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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">ymj</journal-id><journal-title-group><journal-title xml:lang="ru">Якутский медицинский журнал</journal-title><trans-title-group xml:lang="en"><trans-title>Yakut Medical Journal</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">1813-1905</issn><issn pub-type="epub">2312-1017</issn><publisher><publisher-name>ЯНЦ КМП</publisher-name></publisher></journal-meta><article-meta><article-id custom-type="elpub" pub-id-type="custom">ymj-2041</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>СЛУЧАЙ ИЗ ПРАКТИКИ</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>CLINICAL CASE</subject></subj-group></article-categories><title-group><article-title>Клиническое наблюдение прогрессирующего мультифокального лейкоэнцефалита</article-title><trans-title-group xml:lang="en"><trans-title>Clinical observation of progressive multifocal leukoencephalitis</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Попова</surname><given-names>Т. Е.</given-names></name><name name-style="western" xml:lang="en"><surname>Popova</surname><given-names>T. E.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Попова Татьяна Егоровна – к.м.н., доцент</p></bio><email xlink:type="simple">tata2504@yandex.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Николаева</surname><given-names>Т. Я.</given-names></name><name name-style="western" xml:lang="en"><surname>Nikolayeva</surname><given-names>T. Ja.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Николаева Татьяна Яколевна – д.м.н, проф., зав. кафедрой</p></bio><email xlink:type="simple">tyanic@mail.ru</email><xref ref-type="aff" rid="aff-2"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Давыдова</surname><given-names>Т. К.</given-names></name><name name-style="western" xml:lang="en"><surname>Davydova</surname><given-names>T. K.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Давыдова Татьяна Кимовна – к.м.н., врач-ординатор неврологич. Отделения</p></bio><xref ref-type="aff" rid="aff-3"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Пшенникова</surname><given-names>Г. М.</given-names></name><name name-style="western" xml:lang="en"><surname>Pshennikova</surname><given-names>G. M.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Пшенникова Галина Максимовна - к.м.н., доцент-исследователь</p></bio><email xlink:type="simple">pshennikovagm@mail.ru</email><xref ref-type="aff" rid="aff-2"/></contrib></contrib-group><aff xml:lang="ru" id="aff-1"><institution>МИ СВФУ им. М.К. Аммосова</institution><country>Russian Federation</country></aff><aff xml:lang="ru" id="aff-2"><institution>МИ СВФУ</institution><country>Russian Federation</country></aff><aff xml:lang="ru" id="aff-3"><institution>ГБУ РС(Я) РБ№2- ЦЭМП</institution><country>Russian Federation</country></aff><pub-date pub-type="collection"><year>2012</year></pub-date><pub-date pub-type="epub"><day>13</day><month>10</month><year>2025</year></pub-date><volume>0</volume><issue>4</issue><fpage>88</fpage><lpage>92</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Попова Т.Е., Николаева Т.Я., Давыдова Т.К., Пшенникова Г.М., 2025</copyright-statement><copyright-year>2025</copyright-year><copyright-holder xml:lang="ru">Попова Т.Е., Николаева Т.Я., Давыдова Т.К., Пшенникова Г.М.</copyright-holder><copyright-holder xml:lang="en">Popova T.E., Nikolayeva T.J., Davydova T.K., Pshennikova G.M.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://ymj.elpub.ru/jour/article/view/2041">https://ymj.elpub.ru/jour/article/view/2041</self-uri><abstract><p>Представлен относительно редкий клинический случай прогрессирующей мультифокальной лейкоэнцефалопатии с летальным исходом у молодой больной.</p></abstract><trans-abstract xml:lang="en"><p>Rather infrequent clinical case of a progressive multifocal leukoencephalopathy with a lethal outcome at the young patient is submitted.</p></trans-abstract><kwd-group xml:lang="ru"><kwd>прогрессирующий мультифокальный лейкоэнцефалит</kwd><kwd>МРТ</kwd><kwd>РКТ</kwd></kwd-group><kwd-group xml:lang="en"><kwd>a progressive multifocal leukoencephalitis</kwd><kwd>MRI</kwd><kwd>CT</kwd></kwd-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Возможности методов магнитно-резонансной визуализации в диагностике рассеянного склероза / Н.А. 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