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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">ymj</journal-id><journal-title-group><journal-title xml:lang="ru">Якутский медицинский журнал</journal-title><trans-title-group xml:lang="en"><trans-title>Yakut Medical Journal</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">1813-1905</issn><issn pub-type="epub">2312-1017</issn><publisher><publisher-name>ЯНЦ КМП</publisher-name></publisher></journal-meta><article-meta><article-id custom-type="elpub" pub-id-type="custom">ymj-2038</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>НАУЧНЫЕ ОБЗОРЫ И ЛЕКЦИИ</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>SCIENTIFIC REVIEWS AND LECTURES</subject></subj-group></article-categories><title-group><article-title>Биологическая терапия ювенильного ревматоидного артрита</article-title><trans-title-group xml:lang="en"><trans-title>Biological treatment of juvenile rheumatoid arthritis</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Аммосова</surname><given-names>А. М.</given-names></name><name name-style="western" xml:lang="en"><surname>Ammosova</surname><given-names>A. M.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Аммосова Аэлита Михайловна – ст. препод.</p></bio><email xlink:type="simple">aelmma@yandex.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Алексеева</surname><given-names>Е. И.</given-names></name><name name-style="western" xml:lang="en"><surname>Alekseeva</surname><given-names>E. I.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Алексеева Екатерина Иосифовна – д.м.н., проф., зав. отделением</p></bio><xref ref-type="aff" rid="aff-2"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Ханды</surname><given-names>М. В.</given-names></name><name name-style="western" xml:lang="en"><surname>Handu</surname><given-names>M. V.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Ханды Мария Васильевна – проф., зав. кафедрой</p></bio><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Аргунова</surname><given-names>В. М.</given-names></name><name name-style="western" xml:lang="en"><surname>Argunova</surname><given-names>V. M.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Аргунова Вера Маична – зав. отделением</p></bio><xref ref-type="aff" rid="aff-3"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Артамонова</surname><given-names>С. Ю.</given-names></name><name name-style="western" xml:lang="en"><surname>Artamonova</surname><given-names>S. J.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Артамонова Саргылана Юрьевна – доцент</p></bio><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Захарова</surname><given-names>Н. М.</given-names></name><name name-style="western" xml:lang="en"><surname>Zakharova</surname><given-names>N. M.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Захарова Надежда Михайловна – доцент</p></bio><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Маркова</surname><given-names>С. В.</given-names></name><name name-style="western" xml:lang="en"><surname>Markova</surname><given-names>S. V.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Маркова Сардана Валерьевна – доцент</p></bio><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Мунхалова</surname><given-names>Я. А.</given-names></name><name name-style="western" xml:lang="en"><surname>Munhalova</surname><given-names>Ja. A.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Мунхалова Яна Афанасьевна – доцент</p></bio><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Степанова</surname><given-names>Л. А.</given-names></name><name name-style="western" xml:lang="en"><surname>Stepanova</surname><given-names>L. A.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Степанова Лена Анатольевна – доцент</p></bio><xref ref-type="aff" rid="aff-1"/></contrib></contrib-group><aff xml:lang="ru" id="aff-1"><institution>МИ СВФУ им. М.К. Аммосова</institution><country>Russian Federation</country></aff><aff xml:lang="ru" id="aff-2"><institution>Научный центр здоровья РАМН;&#13;
МИ СВФУ им. М.К. Аммосова</institution><country>Russian Federation</country></aff><aff xml:lang="ru" id="aff-3"><institution>РБ№1-НЦМ МЗ РС(Я)</institution><country>Russian Federation</country></aff><pub-date pub-type="collection"><year>2012</year></pub-date><pub-date pub-type="epub"><day>13</day><month>10</month><year>2025</year></pub-date><volume>0</volume><issue>4</issue><fpage>79</fpage><lpage>82</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Аммосова А.М., Алексеева Е.И., Ханды М.В., Аргунова В.М., Артамонова С.Ю., Захарова Н.М., Маркова С.В., Мунхалова Я.А., Степанова Л.А., 2025</copyright-statement><copyright-year>2025</copyright-year><copyright-holder xml:lang="ru">Аммосова А.М., Алексеева Е.И., Ханды М.В., Аргунова В.М., Артамонова С.Ю., Захарова Н.М., Маркова С.В., Мунхалова Я.А., Степанова Л.А.</copyright-holder><copyright-holder xml:lang="en">Ammosova A.M., Alekseeva E.I., Handu M.V., Argunova V.M., Artamonova S.J., Zakharova N.M., Markova S.V., Munhalova J.A., Stepanova L.A.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://ymj.elpub.ru/jour/article/view/2038">https://ymj.elpub.ru/jour/article/view/2038</self-uri><abstract><p>В статье представлена биологическая терапия ревматоидного артрита принципиально новым классом лекарственных средств. В детской ревматологии разрешены 4 генно-инженерных биологических препарата: этанерцепт, адалимумаб, абатацепт, тоцилизумаб.</p></abstract><trans-abstract xml:lang="en"><p>In this article the biological therapy of juvenile rheumatoid arthritis is represented by new class of drugs. Genetically engineered biological drugs are allowed to use in pediatric rheumatology: etanercept, adalimumab, abatacept, tocilizumab.</p></trans-abstract><kwd-group xml:lang="ru"><kwd>ювенильный ревматоидный артрит</kwd><kwd>биологическая терапия</kwd><kwd>дети</kwd></kwd-group><kwd-group xml:lang="en"><kwd>juvenile rheumatoid arthritis</kwd><kwd>biological therapy</kwd><kwd>children</kwd></kwd-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Адалимумаб – новые возможности лечения ювенильного артрита / Е.И. Алексеева, А.О. Лисицин, Н.А. 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