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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">ymj</journal-id><journal-title-group><journal-title xml:lang="ru">Якутский медицинский журнал</journal-title><trans-title-group xml:lang="en"><trans-title>Yakut Medical Journal</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">1813-1905</issn><issn pub-type="epub">2312-1017</issn><publisher><publisher-name>ЯНЦ КМП</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="doi">10.25789/YMJ.2023.81.17</article-id><article-id custom-type="elpub" pub-id-type="custom">ymj-187</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>АКТУАЛЬНАЯ ТЕМА</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>ACTUAL TOPIC</subject></subj-group></article-categories><title-group><article-title>Структура впервые выявленного туберкулеза легких среди взрослого населения Республики Саха (Якутия) в период пандемии новой коронавирусной инфекции</article-title><trans-title-group xml:lang="en"><trans-title>Distribution of clinical forms of newly detected pulmonary tuberculosis among adult population of the Sakha Republic (Yakutia) during the pandemic of novel coronavirus infection</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Прокопьев</surname><given-names>Е. С.</given-names></name><name name-style="western" xml:lang="en"><surname>Prokopiev</surname><given-names>E. S.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Прокопьев Егор Спиридонович – директор, гл. внештат. специалист фтизиатр МЗ РС (Я)</p></bio><bio xml:lang="en"><p>Prokopiev Egor Spiridonovich – Director; Chief non-staff TB specialist (external expert) of the Sakha Republic (Yakutia)</p></bio><email xlink:type="simple">prokopeves@ftiz14.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Зорина</surname><given-names>С. П.</given-names></name><name name-style="western" xml:lang="en"><surname>Zorina</surname><given-names>S. P.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Зорина Светлана Павловна – к.м.н., зав. орг.-аналитич. отделом</p></bio><bio xml:lang="en"><p>Zorina Svetlana Pavlovna – PhD, Head of Organization &amp; Analytics Department</p></bio><email xlink:type="simple">zorinasp@ftiz14.ru</email><xref ref-type="aff" rid="aff-2"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Винокурова</surname><given-names>М. К.</given-names></name><name name-style="western" xml:lang="en"><surname>Vinokurova</surname><given-names>M. K.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Винокурова Мария Константиновна – д.м.н., зам. директора; проф. </p></bio><bio xml:lang="en"><p>Vinokurova Mariya Konstantinovna – MD, Deputy Director for Organization and Science; Professor</p></bio><xref ref-type="aff" rid="aff-3"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Кондратьева</surname><given-names>О. Д.</given-names></name><name name-style="western" xml:lang="en"><surname>Kondratieva</surname><given-names>O. D.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Кондратьева Ольга Дмитриевна – врач-статистик</p></bio><bio xml:lang="en"><p>Kondratieva Olga Dmitrievna – Medical statistician, Organization &amp; Analytics Department</p></bio><xref ref-type="aff" rid="aff-2"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Яковлева</surname><given-names>Л. П.</given-names></name><name name-style="western" xml:lang="en"><surname>Yakovleva</surname><given-names>L. P.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Яковлева Людмила Петровна – к.м.н.; зав. </p></bio><bio xml:lang="en"><p>Yakovleva Ludmila Petrovna – PhD, Head of Republican Tuberculosis Treatment Center</p></bio><xref ref-type="aff" rid="aff-4"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru"><institution>ГБУ РС (Я) НПЦ «Фтизиатрия» им. Е.Н. Андреева</institution><country>Россия</country></aff><aff xml:lang="en"><institution>State-Funded Institution of the Sakha Republic (Yakutia) E.N. Andreev Phthisiatry Research-Practice Center</institution><country>Russian Federation</country></aff></aff-alternatives><aff-alternatives id="aff-2"><aff xml:lang="ru"><institution>ГБУ РС (Я) НПЦ «Фтизиатрия» им. Е.Н. Андреева</institution><country>Россия</country></aff><aff xml:lang="en"><institution>State-Funded Institution of the Sakha Republic (Yakutia) E.N. Andreev Phthisiatry Research Center</institution><country>Russian Federation</country></aff></aff-alternatives><aff-alternatives id="aff-3"><aff xml:lang="ru"><institution>ГБУ РС (Я) НПЦ «Фтизиатрия» им. Е.Н. Андреева; Медицинский институт Северо-Восточного федерального университета им. М.К. Аммосова</institution><country>Россия</country></aff><aff xml:lang="en"><institution>State-Funded Institution of the Sakha Republic (Yakutia) E.N. Andreev Phthisiatry Research Center; Medical Institute of the M.K. Ammosov North-Eastern Federal University</institution><country>Russian Federation</country></aff></aff-alternatives><aff-alternatives id="aff-4"><aff xml:lang="ru"><institution>ГБУ РС (Я) НПЦ «Фтизиатрия» им. Е.Н. Андреева; Республиканский противотуберкулезный диспансер НПЦ «Фтизиатрия»</institution><country>Россия</country></aff><aff xml:lang="en"><institution>State-Funded Institution of the Sakha Republic (Yakutia) E.N. Andreev Phthisiatry Research Center</institution><country>Russian Federation</country></aff></aff-alternatives><pub-date pub-type="collection"><year>2023</year></pub-date><pub-date pub-type="epub"><day>05</day><month>02</month><year>2025</year></pub-date><volume>0</volume><issue>1</issue><fpage>67</fpage><lpage>71</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Прокопьев Е.С., Зорина С.П., Винокурова М.К., Кондратьева О.Д., Яковлева Л.П., 2025</copyright-statement><copyright-year>2025</copyright-year><copyright-holder xml:lang="ru">Прокопьев Е.С., Зорина С.П., Винокурова М.К., Кондратьева О.Д., Яковлева Л.П.</copyright-holder><copyright-holder xml:lang="en">Prokopiev E.S., Zorina S.P., Vinokurova M.K., Kondratieva O.D., Yakovleva L.P.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://ymj.elpub.ru/jour/article/view/187">https://ymj.elpub.ru/jour/article/view/187</self-uri><abstract><p>В статье проанализирована эпидемическая ситуация по туберкулезу и клиническая структура впервые выявленного туберкулеза легких среди взрослого населения, как в целом на территории Республики Саха (Якутия), так и с выделением Арктической зоны в период ограничительных мероприятий, организованных для борьбы с пандемией новой коронавирусной инфекции COVID-19.</p><p>В период усиления противоэпидемических мероприятий и санитарных мер произошло существенное снижение основных эпидемических показателей по туберкулезу, но при этом усугубилась ситуация по своевременному выявлению туберкулеза среди населения. Увеличилась доля впервые выявленных взрослых больных с деструктивными формами туберкулеза легких и бактериовыделением при самостоятельном обращении в медицинские организации.</p><p>Выявлена статистически значимая корреляционная связь между показателями объемов и качества профилактических осмотров населения на туберкулез и отягощенной клинической структурой впервые выявленных больных туберкулезом лиц.</p></abstract><trans-abstract xml:lang="en"><p>With an aim to study the impact of restrictive measures against COVID-19 pandemic on epidemiologic situation with tuberculosis (TB), we analyzed key epidemiological data and distribution of clinical forms of newly detected pulmonary TB (PTB) among adult population of the Sakha Republic (Yakutia), with a separate analysis for the Arctic zone, as an example of a territory with low population density and limited transport accessibility.</p><p>For the study purpose, we used data from federal statistical recording and reporting forms, and data from TB medical patient database of the Sakha Republic (Yakutia). Rates for adult newly diagnosed PTB cases were analyzed for two pandemic years (2020-2021) against two pre-pandemic years (2018-2019). Statistical methods of choice were Pearson’s correlation coefficient and data weighing by chest x-ray coverage trend.</p><p>Study findings showed that the period of strengthened anti-epidemic and sanitation measures against novel coronavirus infection (COVID-19) was followed by substantial decrease in epidemiologic rates for TB, but, at the same time, profoundly deteriorated situation with delays in TB detection.</p><p>In the Arctic zone of Yakutia, epidemiologic rates for TB were showing decrease during restrictive measures, but generally remain higher than mean republic rates.</p><p>Increase in proportion of new adult patients with advanced disease forms was observed, together with the fact the TB detection rates in the Arctic zone were lower compared to mean republic detection rates.</p><p>The scope and quality of preventive checkups for TB correlated in a statistically significant way with the distribution of clinical forms of TB among newly diagnosed patients.</p><p>In conclusion, to reduce the rate of detections of MTB-positive destructive TB forms, prevention and detection measures will need to be strengthened, and should include universal annual chest x-ray screening of the population aged 15 and above.</p></trans-abstract><kwd-group xml:lang="ru"><kwd>туберкулез легких</kwd><kwd>выявление</kwd><kwd>новая коронавирусная инфекция</kwd><kwd>COVID-19</kwd><kwd>Якутия</kwd><kwd>Арктика</kwd></kwd-group><kwd-group xml:lang="en"><kwd>pulmonary tuberculosis</kwd><kwd>detection</kwd><kwd>novel coronavirus infection</kwd><kwd>COVID-19</kwd><kwd>Yakutia</kwd><kwd>Arctic</kwd></kwd-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Богородская Е.М. 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