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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">ymj</journal-id><journal-title-group><journal-title xml:lang="ru">Якутский медицинский журнал</journal-title><trans-title-group xml:lang="en"><trans-title>Yakut Medical Journal</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">1813-1905</issn><issn pub-type="epub">2312-1017</issn><publisher><publisher-name>ЯНЦ КМП</publisher-name></publisher></journal-meta><article-meta><article-id custom-type="elpub" pub-id-type="custom">ymj-1869</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>ГИГИЕНА, САНИТАРИЯ, ЭПИДЕМИОЛОГИЯ И МЕДИЦИНСКАЯ ЭКОЛОГИЯ</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>HYGIENE, SANITATION, EPIDEMIOLOGY AND MEDICAL ECOLOGY</subject></subj-group></article-categories><title-group><article-title>Интеграционный подход к изучению многолетней динамики заболеваемости ВИЧ-инфекцией, туберкулезом и их сочетанными формами населения Республики Саха (Якутия)</article-title><trans-title-group xml:lang="en"><trans-title>Integrated approach to the study of long-term dynamics of HIV infection, tuberculosis and their combined forms morbidity of the RS (Y) population</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Бурнашева</surname><given-names>Л. С.</given-names></name><name name-style="western" xml:lang="en"><surname>Yakovlev</surname><given-names>A. A.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Бурнашева Любовь Степановна – заочный аспирант, гл. специалист-эксперт</p></bio><bio xml:lang="en"><p>Anatoly Alexandrovich Yakovlev, Doctor of Medicine, Professor, Professor at the Chair of Epidemiology and Military Epidemiology</p><p>Home address: 690087, Vladivostok, Kotelnikova, 8, kv. 40, mobile phone +7 908 970 93 37</p></bio><email xlink:type="simple">burnashevals@mail.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Яковлев</surname><given-names>А. А.</given-names></name><name name-style="western" xml:lang="en"><surname>Burnasheva</surname><given-names>L. S.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Яковлев Анатолий Александрович – д.м.н., проф.</p></bio><bio xml:lang="en"><p>Lyubov Stepanovna Burnasheva, correspondence post-graduate student at the Chair of Epidemiology and Military Epidemiology</p><p>Chief Expert at the Sector of Epidemiological Monitoring</p><p>Home address: 677018, Yakutsk, Yaroslavskogo, 39/1, kv. 77; mobile phone: + 7 964 424 20 11</p></bio><email xlink:type="simple">yakovlev-epid@yandex.ru</email><xref ref-type="aff" rid="aff-2"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru"><institution>Тихоокеанский гос. мед. университет Министерства здравоохранения РФ;&#13;
Управление Роспотребнадзора по РС(Я)</institution><country>Россия</country></aff><aff xml:lang="en"><institution>Pacific State Medical University, Ministry of Health of the RF</institution><country>Russian Federation</country></aff></aff-alternatives><aff-alternatives id="aff-2"><aff xml:lang="ru"><institution>Тихоокеанский гос. мед. университет Министерства здравоохранения РФ</institution><country>Россия</country></aff><aff xml:lang="en"><institution>Pacific State Medical University, Ministry of Health of the RF;&#13;
Rospotrebnadzor Department in the Sakha Republic (Yakutia)</institution><country>Russian Federation</country></aff></aff-alternatives><pub-date pub-type="collection"><year>2013</year></pub-date><pub-date pub-type="epub"><day>05</day><month>10</month><year>2025</year></pub-date><volume>0</volume><issue>4</issue><fpage>57</fpage><lpage>60</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Бурнашева Л.С., Яковлев А.А., 2025</copyright-statement><copyright-year>2025</copyright-year><copyright-holder xml:lang="ru">Бурнашева Л.С., Яковлев А.А.</copyright-holder><copyright-holder xml:lang="en">Yakovlev A.A., Burnasheva L.S.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://ymj.elpub.ru/jour/article/view/1869">https://ymj.elpub.ru/jour/article/view/1869</self-uri><abstract><p>В работе на основе интеграционного метода представлена динамика заболеваемости туберкулезом и ВИЧ-инфекцией и их сочетанными формами в Республике Саха (Якутия). Выявлены различия в заболеваемости туберкулезом коренного и пришлого населения. В результате анализа данных литературы представлены возможные механизмы взаимодействия микобактерий туберкулеза и ВИЧ и их отражение в эпидемическом процессе. Показана важная роль микст - форм туберкулеза и ВИЧ-инфекции в его развитии.</p></abstract><trans-abstract xml:lang="en"><p>In the paper the authors show the dynamics of the incidence of tuberculosis, HIV infection and their mixed forms in the Republic Sakha (Yakutia) on the base of the integration method. Differences in the TB incidence of native and non-native population are revealed. The authors present the possible mechanisms of interaction between M. tuberculosis and HIV, and their reflection in the epidemic process basing on an analysis of the literature review. The important role of tuberculosis mixed-forms and HIV infection in its development is shown.</p></trans-abstract><kwd-group xml:lang="ru"><kwd>эпидемиология</kwd><kwd>ВИЧ-инфекция</kwd><kwd>туберкулез</kwd><kwd>микст-формы</kwd><kwd>интеграционный метод</kwd></kwd-group><kwd-group xml:lang="en"><kwd>epidemiology</kwd><kwd>HIV infection</kwd><kwd>tuberculosis</kwd><kwd>mixed-forms</kwd><kwd>integration method</kwd></kwd-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Анализ больных туберкулезом, сочетанным с ВИЧ-инфекцией, в Московском регионе / А.В. Кравченко, А.И. Щелканова, Т.Н. Ермак [и др.] // Проблемы туберкулеза и болезней легких. – 2005. - №10. – С. 34-37.</mixed-citation><mixed-citation xml:lang="en">Analysis of the tuberculosis patients with HIV infection in Moscow area / Kravchenko A.V., Shhelkanova A.I., Ermak T.N. 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